GB1351836A - Method of measuring serum thyroxine and apparatus for use therein - Google Patents
Method of measuring serum thyroxine and apparatus for use thereinInfo
- Publication number
- GB1351836A GB1351836A GB3027671A GB3027671A GB1351836A GB 1351836 A GB1351836 A GB 1351836A GB 3027671 A GB3027671 A GB 3027671A GB 3027671 A GB3027671 A GB 3027671A GB 1351836 A GB1351836 A GB 1351836A
- Authority
- GB
- United Kingdom
- Prior art keywords
- thyroxine
- column
- serum
- determination
- gel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- XUIIKFGFIJCVMT-GFCCVEGCSA-N D-thyroxine Chemical compound IC1=CC(C[C@@H](N)C(O)=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-GFCCVEGCSA-N 0.000 title abstract 9
- 229940034208 thyroxine Drugs 0.000 title abstract 9
- XUIIKFGFIJCVMT-UHFFFAOYSA-N thyroxine-binding globulin Natural products IC1=CC(CC([NH3+])C([O-])=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-UHFFFAOYSA-N 0.000 title abstract 9
- 210000002966 serum Anatomy 0.000 title abstract 5
- 239000004698 Polyethylene Substances 0.000 abstract 2
- 229920005654 Sephadex Polymers 0.000 abstract 2
- -1 polyethylene Polymers 0.000 abstract 2
- 229920000573 polyethylene Polymers 0.000 abstract 2
- 230000002285 radioactive effect Effects 0.000 abstract 2
- 230000000717 retained effect Effects 0.000 abstract 2
- 102000002572 Alpha-Globulins Human genes 0.000 abstract 1
- 108010068307 Alpha-Globulins Proteins 0.000 abstract 1
- 241000283690 Bos taurus Species 0.000 abstract 1
- BRLQWZUYTZBJKN-UHFFFAOYSA-N Epichlorohydrin Chemical compound ClCC1CO1 BRLQWZUYTZBJKN-UHFFFAOYSA-N 0.000 abstract 1
- 239000012670 alkaline solution Substances 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 239000012888 bovine serum Substances 0.000 abstract 1
- 108010074605 gamma-Globulins Proteins 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/804—Radioisotope, e.g. radioimmunoassay
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/825—Pretreatment for removal of interfering factors from sample
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/826—Additives, e.g. buffers, diluents, preservatives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5100570A | 1970-06-29 | 1970-06-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1351836A true GB1351836A (en) | 1974-05-01 |
Family
ID=21968790
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB3027671A Expired GB1351836A (en) | 1970-06-29 | 1971-06-28 | Method of measuring serum thyroxine and apparatus for use therein |
Country Status (11)
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0021214A1 (en) * | 1979-06-21 | 1981-01-07 | Ames-Yissum Limited | Multilayer column chromatography specific binding assay method, test device and test kit |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3929410A (en) * | 1970-11-09 | 1975-12-30 | Benjamin Schloss | Analytical process |
DE2129553A1 (de) * | 1971-06-15 | 1972-12-21 | Merck Patent Gmbh | Verfahren zur Bestimmung von Thyroxin |
NL7112927A (enrdf_load_stackoverflow) * | 1971-09-21 | 1973-03-23 | ||
US3753655A (en) * | 1971-11-09 | 1973-08-21 | B Schreiber | Process for isolation and separation of thyroid hormones |
US3911096A (en) * | 1972-06-23 | 1975-10-07 | Professional Staff Ass Of The | Radioimmunoassay for measurement of thyroxine (T{HD 4{B ) and triiodothyonine (T{HD 3{B ) in blood serum |
USRE32098E (en) * | 1972-06-23 | 1986-03-25 | Research And Education Institute, Inc. | Radioimmunoassay for measurement of thyroxine (T4) and triiodothyronine (T3) in blood serum |
IL42105A (en) * | 1973-04-25 | 1976-08-31 | Yissum Res Dev Co | Process for determination of triiodothyronine |
GB1412274A (en) * | 1973-05-29 | 1975-11-05 | Bio Rad Laboratories | Radioactive determination of serum thyroxine |
US3941564A (en) * | 1973-09-13 | 1976-03-02 | Miles Laboratories, Inc. | Method for assessing thyroid function |
US4230797A (en) * | 1975-04-28 | 1980-10-28 | Miles Laboratories, Inc. | Heterogenous specific binding assay employing a coenzyme as label |
IT1206354B (it) * | 1977-03-10 | 1989-04-21 | Lepetit Spa | Corredo da usarsi per la determinazione degli ormoni liberi nei fluidi biologici |
US4170454A (en) * | 1978-03-30 | 1979-10-09 | Union Carbide Corporation | Process for the preparation of a solid-phase radioimmunoassay support and use thereof |
US4492751A (en) * | 1978-04-10 | 1985-01-08 | Miles Laboratories, Inc. | Heterogenous specific binding assay employing an enzyme substrate as label |
US4318980A (en) * | 1978-04-10 | 1982-03-09 | Miles Laboratories, Inc. | Heterogenous specific binding assay employing a cycling reactant as label |
US4225576A (en) * | 1978-11-20 | 1980-09-30 | Miles Laboratories, Inc. | Combined radioimmunoassay for triiodothyronine and thyroxine |
US5217903A (en) * | 1990-05-15 | 1993-06-08 | Trustees Of Boston University | Measuring connective tissue breakdown products in body fluids |
KR20020065698A (ko) * | 2001-02-07 | 2002-08-14 | 주식회사 바이오라인 | 방사면역측정법을 이용한 갑상선 호르몬 측정키트 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3507618A (en) * | 1964-11-27 | 1970-04-21 | Squibb & Sons Inc | Apparatus and method for determining thyroid function |
US3451777A (en) * | 1965-08-20 | 1969-06-24 | Walter Di Giulio | Method and apparatus for determining the thyroid hormone content of blood |
-
1970
- 1970-06-29 US US51005A patent/US3659104A/en not_active Expired - Lifetime
-
1971
- 1971-05-26 ZA ZA713408A patent/ZA713408B/xx unknown
- 1971-06-14 IL IL37046A patent/IL37046A/xx unknown
- 1971-06-22 HU HUII65A patent/HU166424B/hu unknown
- 1971-06-26 ES ES392664A patent/ES392664A1/es not_active Expired
- 1971-06-28 SE SE7108334A patent/SE392346B/xx unknown
- 1971-06-28 FR FR7123530A patent/FR2100008A5/fr not_active Expired
- 1971-06-28 JP JP4640271A patent/JPS5331399B1/ja active Pending
- 1971-06-28 GB GB3027671A patent/GB1351836A/en not_active Expired
- 1971-06-28 CA CA116,818A patent/CA955159A/en not_active Expired
- 1971-06-28 DE DE2132112A patent/DE2132112C3/de not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0021214A1 (en) * | 1979-06-21 | 1981-01-07 | Ames-Yissum Limited | Multilayer column chromatography specific binding assay method, test device and test kit |
Also Published As
Publication number | Publication date |
---|---|
DE2132112A1 (de) | 1972-01-27 |
ZA713408B (en) | 1972-01-26 |
ES392664A1 (es) | 1973-08-01 |
CA955159A (en) | 1974-09-24 |
IL37046A (en) | 1974-05-16 |
DE2132112C3 (de) | 1974-09-19 |
SE392346B (sv) | 1977-03-21 |
HU166424B (enrdf_load_stackoverflow) | 1975-03-28 |
US3659104A (en) | 1972-04-25 |
FR2100008A5 (enrdf_load_stackoverflow) | 1972-03-17 |
JPS5331399B1 (enrdf_load_stackoverflow) | 1978-09-02 |
DE2132112B2 (de) | 1974-02-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |