GB1347375A - Phenylalanine derivatives and a process for the manufacture thereof - Google Patents

Phenylalanine derivatives and a process for the manufacture thereof

Info

Publication number
GB1347375A
GB1347375A GB5033571A GB5033571A GB1347375A GB 1347375 A GB1347375 A GB 1347375A GB 5033571 A GB5033571 A GB 5033571A GB 5033571 A GB5033571 A GB 5033571A GB 1347375 A GB1347375 A GB 1347375A
Authority
GB
United Kingdom
Prior art keywords
group
substituted
alkyl
alkenyl
alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5033571A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB1347375A publication Critical patent/GB1347375A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/04—Esters of boric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB5033571A 1970-10-30 1971-10-29 Phenylalanine derivatives and a process for the manufacture thereof Expired GB1347375A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1604870A CH562199A5 (cg-RX-API-DMAC10.html) 1970-10-30 1970-10-30

Publications (1)

Publication Number Publication Date
GB1347375A true GB1347375A (en) 1974-02-27

Family

ID=4414060

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5033571A Expired GB1347375A (en) 1970-10-30 1971-10-29 Phenylalanine derivatives and a process for the manufacture thereof

Country Status (12)

Country Link
US (1) US3859331A (cg-RX-API-DMAC10.html)
AU (1) AU461826B2 (cg-RX-API-DMAC10.html)
BE (1) BE774678A (cg-RX-API-DMAC10.html)
CA (1) CA996131A (cg-RX-API-DMAC10.html)
CH (1) CH562199A5 (cg-RX-API-DMAC10.html)
DE (1) DE2153800A1 (cg-RX-API-DMAC10.html)
FR (1) FR2111942B1 (cg-RX-API-DMAC10.html)
GB (1) GB1347375A (cg-RX-API-DMAC10.html)
IL (1) IL37704A (cg-RX-API-DMAC10.html)
NL (1) NL7114948A (cg-RX-API-DMAC10.html)
SE (2) SE7506821L (cg-RX-API-DMAC10.html)
ZA (1) ZA715981B (cg-RX-API-DMAC10.html)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2120533C1 (ru) * 1997-06-06 1998-10-20 Открытое акционерное общество Верхнесалдинское металлургическое производственное объединение Термовкладыш
JP2010532751A (ja) * 2007-07-06 2010-10-14 プロキシマジェン エルティーディー アミノ酸誘導体
CN105143174A (zh) * 2013-03-15 2015-12-09 苏州泰飞尔医药有限公司 治疗帕金森疾病的新型高穿透力药物和医药组合物
JP2024041865A (ja) * 2017-12-28 2024-03-27 テックフィールズ ファーマ カンパニー リミテッド パ－キンソン病治療用の新規高透過薬物及びその組成物
US12036199B1 (en) * 2023-07-05 2024-07-16 Dynamic Biologics Inc. Levodopa fatty acid derivatives, formulations thereof, and their uses for the treatment of Parkinson's disease

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4051169A (en) * 1973-09-25 1977-09-27 Merck & Co., Inc. Amino acid esters
US3947590A (en) * 1973-10-23 1976-03-30 Abbott Laboratories Compositions and methods of increasing renal blood flow with gamma-glutamyl amide of dopamine
US4254273A (en) * 1975-06-11 1981-03-03 Merck & Co., Inc. Process for preparing esters of α-methyl-3,4-dihydroxyphenylalanine
US4156734A (en) * 1976-02-13 1979-05-29 Merck & Co., Inc. Antihypertensive compositions containing an aryl-substituted alanine azo and an arylhydrazino-propionic acid
US4065572A (en) * 1976-02-13 1977-12-27 Merck & Co., Inc. Amino acids and esters thereof useful as antihypertensive agents
CA1108180A (en) * 1976-07-21 1981-09-01 Hamao Umezawa Analogs of bestatin
US4228303A (en) * 1979-06-25 1980-10-14 Morton-Norwich Products, Inc. 3-(3,4-Dihydroxyphenyl)-N-(4-nitrobenzyl)alanine hydrobromide
US4275219A (en) * 1979-09-24 1981-06-23 Interx Research Corporation Novel process and intermediates useful in the preparation of sympathomimetic amines
US4338455A (en) * 1981-02-11 1982-07-06 Merck & Co., Inc. Novel process and intermediates useful in the preparation of sympathomimetic amines
US4360533A (en) * 1981-12-14 1982-11-23 Merck & Co., Inc. Glyceryl ester of 1-methyl-2-(3,4-dihydroxyphenyl)alanine
JPS59112949A (ja) * 1982-12-20 1984-06-29 Microbial Chem Res Found 新規なｌ−スレオ−アドレナリン酸
JPH02138A (ja) * 1987-09-18 1990-01-05 Banyu Pharmaceut Co Ltd Ｌ‐ドーパ誘導体
US5098999A (en) * 1989-08-23 1992-03-24 Hitachi Chemical Company Amino-protected dopa derivative and production thereof
US5393908A (en) * 1992-06-25 1995-02-28 Satyamurthy; Nagichettiar Synthesis of N-formyl-3,4-di-t-butoxycarbonyloxy-6-(trimethylstannyl)-L-phenylalanine ethyl ester and its regioselective radiofluorodestannylation to 6-[18 F]fluoro-L-dopa
FR2724654B1 (fr) * 1994-09-16 1997-12-12 Roussel Uclaf Nouveaux derives de l'acide gallique, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
US7022872B2 (en) * 2003-12-19 2006-04-04 Molecular Technologies, Inc. Method for making fluorine labeled L-Dopa
DE102005022276A1 (de) * 2005-05-13 2006-11-16 Ellneuroxx Ltd. Derivate von Dihydroxyphenylalanin
GB0715712D0 (en) * 2007-08-11 2007-09-19 Proximagen Ltd Amino acid derivatives
BR112013013551A2 (pt) * 2010-12-02 2016-10-11 Ono Pharmaceutical Co composto e uso médico do mesmo
US9447407B2 (en) 2011-02-02 2016-09-20 Agency For Science, Technology And Research Double coating procedure for the membranes of bioartificial kidneys
CN113042083A (zh) * 2021-03-25 2021-06-29 西南民族大学 一种钯基单原子催化剂及其制备与应用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3488363A (en) * 1965-10-22 1970-01-06 Merck & Co Inc Preparation of alpha-methylphenyl alanines
CH475193A (de) * 1966-06-07 1969-07-15 Hoffmann La Roche Verfahren zur Herstellung von Phenylalaninderivaten
US3734952A (en) * 1968-12-27 1973-05-22 Hoffmann La Roche Preparation of l-dopa

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2120533C1 (ru) * 1997-06-06 1998-10-20 Открытое акционерное общество Верхнесалдинское металлургическое производственное объединение Термовкладыш
JP2010532751A (ja) * 2007-07-06 2010-10-14 プロキシマジェン エルティーディー アミノ酸誘導体
CN105143174A (zh) * 2013-03-15 2015-12-09 苏州泰飞尔医药有限公司 治疗帕金森疾病的新型高穿透力药物和医药组合物
US11084813B2 (en) 2013-03-15 2021-08-10 Techfields Pharma Co., Ltd. High penetration drugs and their compositions thereof for treatment of Parkinson diseases
US11685739B2 (en) 2013-03-15 2023-06-27 Techfields Pharma Co., Ltd. High penetration drugs and their compositions thereof for treatment of Parkinson diseases
JP2024041865A (ja) * 2017-12-28 2024-03-27 テックフィールズ ファーマ カンパニー リミテッド パ－キンソン病治療用の新規高透過薬物及びその組成物
US12036199B1 (en) * 2023-07-05 2024-07-16 Dynamic Biologics Inc. Levodopa fatty acid derivatives, formulations thereof, and their uses for the treatment of Parkinson's disease
JP2025013734A (ja) * 2023-07-05 2025-01-27 ダイナミック バイオロジクス インコーポレイテッド レボドパ脂肪酸誘導体、その製剤、及びパーキンソン病の治療のためのそれらの使用

Also Published As

Publication number Publication date
IL37704A0 (en) 1971-11-29
AU3331871A (en) 1973-03-15
CA996131A (en) 1976-08-31
BE774678A (fr) 1972-05-02
AU461826B2 (en) 1975-06-05
DE2153800A1 (cg-RX-API-DMAC10.html) 1972-05-04
ZA715981B (en) 1972-06-28
NL7114948A (cg-RX-API-DMAC10.html) 1972-05-03
IL37704A (en) 1975-10-15
US3859331A (en) 1975-01-07
FR2111942A1 (cg-RX-API-DMAC10.html) 1972-06-09
FR2111942B1 (cg-RX-API-DMAC10.html) 1975-08-01
SE7506820L (sv) 1975-06-13
SE7506821L (sv) 1975-06-13
CH562199A5 (cg-RX-API-DMAC10.html) 1975-05-30

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees