GB1344960A - Optically active dervatives of cyclohex-1-ene - Google Patents
Optically active dervatives of cyclohex-1-eneInfo
- Publication number
- GB1344960A GB1344960A GB2984672A GB2984672A GB1344960A GB 1344960 A GB1344960 A GB 1344960A GB 2984672 A GB2984672 A GB 2984672A GB 2984672 A GB2984672 A GB 2984672A GB 1344960 A GB1344960 A GB 1344960A
- Authority
- GB
- United Kingdom
- Prior art keywords
- ene
- optically active
- compound
- dervatives
- cyclohex
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1344960 (+) - 3r - N - monomethylamino- 4c - phenyl 4t - ethoxycarbonylcyclohex - 1 - ene WARNER-LAMBERT CO 26 June 1972 [30 June 1971] 29846/72 Heading C2C The novel title compound and acid addition salts thereof such as the hydrochloride and the D- or L-o,o-dibenzoyltartrates are prepared by resolution of the receamic compound with an optically active o,o-dibenzoyltartaric acid or by monodemethylation of (+)-3r-N-dimethylamino - 4c - phenyl - 4t - ethoxycarbonylcyclohex- 1-ene by bromination in a chlorinated hydrocarbon at - 15‹ to 20‹ C. followed by treatment with water. Pharmaceutical compositions in conventional forms for oral, rectal or parenteral administration and having analgesic activity comprise the above novel compound or a salt thereof and a carrier or diluent.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19712132562 DE2132562C (en) | 1971-06-30 | (+) 3r N monomethylamino 4c phenyl 4t athoxycarbonyl cyclohexene (1), its D or L O, O dibenzoyl tartrate, hydro chloride or other salts of physiologically harmless acids and processes for their production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1344960A true GB1344960A (en) | 1974-01-23 |
Family
ID=5812271
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2984672A Expired GB1344960A (en) | 1971-06-30 | 1972-06-26 | Optically active dervatives of cyclohex-1-ene |
Country Status (5)
| Country | Link |
|---|---|
| AU (1) | AU460866B2 (en) |
| CA (1) | CA965799A (en) |
| DK (1) | DK134752C (en) |
| FR (1) | FR2143923B1 (en) |
| GB (1) | GB1344960A (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4002000A (en) * | 1975-06-30 | 1977-01-11 | Palmer-Shile Company | Beam construction and method of manufacture |
-
1972
- 1972-06-26 GB GB2984672A patent/GB1344960A/en not_active Expired
- 1972-06-26 AU AU43909/72A patent/AU460866B2/en not_active Expired
- 1972-06-29 DK DK325272A patent/DK134752C/en not_active IP Right Cessation
- 1972-06-29 CA CA146,078A patent/CA965799A/en not_active Expired
- 1972-06-30 FR FR7223714A patent/FR2143923B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK134752B (en) | 1977-01-10 |
| FR2143923A1 (en) | 1973-02-09 |
| AU460866B2 (en) | 1975-05-08 |
| DK134752C (en) | 1977-07-04 |
| AU4390972A (en) | 1974-01-03 |
| DE2132562B1 (en) | 1972-12-21 |
| CA965799A (en) | 1975-04-08 |
| FR2143923B1 (en) | 1976-03-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |