SE7415496L - - Google Patents

Info

Publication number
SE7415496L
SE7415496L SE7415496A SE7415496A SE7415496L SE 7415496 L SE7415496 L SE 7415496L SE 7415496 A SE7415496 A SE 7415496A SE 7415496 A SE7415496 A SE 7415496A SE 7415496 L SE7415496 L SE 7415496L
Authority
SE
Sweden
Prior art keywords
bis
dec
hexamethylene
diamide
compounds
Prior art date
Application number
SE7415496A
Inventor
J Pless
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1776973A external-priority patent/CH588441A5/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of SE7415496L publication Critical patent/SE7415496L/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1490558 Phenethylamine derivatives SANDOZ Ltd 16 Dec 1974 [19 Dec 1973 23 Oct 1974 (2)] 54157/74 Heading C2C Compounds of the general formula (R 1,2 =H, C 1-5 alkyl) and their salts are prepared by (a) subjecting a corresponding bisdiether to acidolysis or hydrogenolysis or (b) reducing the corresponding bis-amide in which the (CH 2 ) 6 groups are replaced by (CH 2 ) 5 CO, optionally followed by salt formation. The preparation of starting materials for processes (a) and (b) and 2,4,5-trichlorophenyl hydrogen adipate, N 2 ,N<SP>1</SP> 2 -bis-(3,4-dimethoxyphenethyl) - N 1 ,N<SP>1</SP> 1 - hexamethylene bis - (adipic azid diamide) and hexamethylene - N,N<SP>1</SP> - 1 - bromocaproic acid diamide is described. The above compounds are antihypotensives, and may be administered in the form of pharmaceutical preparations containing them in association with a carrier.
SE7415496A 1973-12-19 1974-12-10 SE7415496L (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH1776973A CH588441A5 (en) 1973-12-19 1973-12-19 Antihypertensive hexamethylene-diamine derivs. - N,N'-bis(6-2-(3,4-dihydroxyphenyl)-ethylamino)-hexyl)-hexamethylene- ne-diamines and their acid addition salts
CH1417374 1974-10-23
CH1417474 1974-10-23

Publications (1)

Publication Number Publication Date
SE7415496L true SE7415496L (en) 1975-06-23

Family

ID=27177125

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7415496A SE7415496L (en) 1973-12-19 1974-12-10

Country Status (12)

Country Link
JP (1) JPS5093930A (en)
AU (1) AU7652474A (en)
DD (1) DD119413A5 (en)
DE (1) DE2458222A1 (en)
DK (1) DK641174A (en)
FI (1) FI355174A (en)
FR (1) FR2255057B1 (en)
GB (1) GB1490558A (en)
IL (1) IL46266A0 (en)
NL (1) NL7416235A (en)
NO (1) NO744465L (en)
SE (1) SE7415496L (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3476196D1 (en) * 1983-01-21 1989-02-23 Fisons Plc Aromatic amines
US5753714A (en) * 1987-02-03 1998-05-19 Merrell Pharmaceuticals Inc. Polyamine derivatives
ZA88600B (en) * 1987-02-03 1988-07-28 Merrell Dow Pharmaceuticals Inc. Novel polyamine derivatives
JP2004292367A (en) * 2003-03-27 2004-10-21 Takuma Co Ltd 2,4,5-trichlorophenoxyalkylcarboxylic acid and immunoassay for dioxins using the same

Also Published As

Publication number Publication date
NL7416235A (en) 1975-06-23
FR2255057A1 (en) 1975-07-18
AU7652474A (en) 1976-06-17
NO744465L (en) 1975-07-14
GB1490558A (en) 1977-11-02
JPS5093930A (en) 1975-07-26
IL46266A0 (en) 1975-03-13
DE2458222A1 (en) 1975-07-03
FR2255057B1 (en) 1978-07-21
DD119413A5 (en) 1976-04-20
FI355174A (en) 1975-06-20
DK641174A (en) 1975-08-25

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