GB1230468A - - Google Patents
Info
- Publication number
- GB1230468A GB1230468A GB1230468DA GB1230468A GB 1230468 A GB1230468 A GB 1230468A GB 1230468D A GB1230468D A GB 1230468DA GB 1230468 A GB1230468 A GB 1230468A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- salt
- amidinohydrazine
- sandoz
- benzylidene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
- C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1,230,468. Benzylidene amidinohydrazine derivatives. SANDOZ Ltd. 21 Oct., 1968 [13 Nov., 1967], No. 49842/68. Heading C2C. Novel compounds of formula wherein one of R 1 , R 2 or R 3 is CF 3 and others are CF 3 , H, F or Cl and R 4 is H, Cl or F with the proviso that at least one of R 1 , R 2 , R 3 or R 4 is H are prepared by reaction of a benzaldehyde of formula and amino guanidine or a salt thereof optionally followed by conversion to the base. Pharmaceutical compositions in conventional forms for oral or parenteral administration and having hypotensive activity comprise an above novel compound or a pharmaceutically acceptable salt thereof on a carrier therefor.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68253567A | 1967-11-13 | 1967-11-13 | |
| US74430868A | 1968-07-12 | 1968-07-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1230468A true GB1230468A (en) | 1971-05-05 |
Family
ID=27102912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1230468D Expired GB1230468A (en) | 1967-11-13 | 1968-10-21 |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE723724A (en) |
| CH (1) | CH500953A (en) |
| DE (1) | DE1808033A1 (en) |
| ES (1) | ES360153A1 (en) |
| FR (2) | FR1591725A (en) |
| GB (1) | GB1230468A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8148429B2 (en) | 2000-08-07 | 2012-04-03 | Anamar Ab | Use of benzylideneaminoguanidines and hydroxyguanidines as melanocortin receptor ligands |
-
1968
- 1968-10-18 CH CH1561068A patent/CH500953A/en not_active IP Right Cessation
- 1968-10-21 GB GB1230468D patent/GB1230468A/en not_active Expired
- 1968-11-09 DE DE19681808033 patent/DE1808033A1/en active Pending
- 1968-11-12 ES ES360153A patent/ES360153A1/en not_active Expired
- 1968-11-12 FR FR1591725D patent/FR1591725A/fr not_active Expired
- 1968-11-12 BE BE723724D patent/BE723724A/xx not_active Expired
-
1969
- 1969-02-11 FR FR183248A patent/FR8326M/fr not_active Expired
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8148429B2 (en) | 2000-08-07 | 2012-04-03 | Anamar Ab | Use of benzylideneaminoguanidines and hydroxyguanidines as melanocortin receptor ligands |
| US8309609B2 (en) | 2000-08-07 | 2012-11-13 | Anamar Ab | Use of benzylideneaminoguanidines and hydroxyguanidines as melanocortin receptor ligands |
| US8410174B2 (en) | 2000-08-07 | 2013-04-02 | Anamar Ab | Method for treating arthritis |
| US9227927B2 (en) | 2000-08-07 | 2016-01-05 | Anamar Ab | Method of treating inflammation |
Also Published As
| Publication number | Publication date |
|---|---|
| ES360153A1 (en) | 1970-11-01 |
| CH500953A (en) | 1970-12-31 |
| FR8326M (en) | 1970-12-07 |
| DE1808033A1 (en) | 1969-06-26 |
| BE723724A (en) | 1969-05-12 |
| FR1591725A (en) | 1970-05-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |