GB1343831A - Pharmaceutical use of certain substituted biguanides - Google Patents
Pharmaceutical use of certain substituted biguanidesInfo
- Publication number
- GB1343831A GB1343831A GB2281571A GB2281571A GB1343831A GB 1343831 A GB1343831 A GB 1343831A GB 2281571 A GB2281571 A GB 2281571A GB 2281571 A GB2281571 A GB 2281571A GB 1343831 A GB1343831 A GB 1343831A
- Authority
- GB
- United Kingdom
- Prior art keywords
- atoms
- formula
- alkyl
- alkenyl
- biguanides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940123208 Biguanide Drugs 0.000 title abstract 3
- 150000004283 biguanides Chemical class 0.000 title abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- 125000003342 alkenyl group Chemical group 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 2
- 150000001412 amines Chemical class 0.000 abstract 2
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000001769 aryl amino group Chemical group 0.000 abstract 1
- JIRRNZWTWJGJCT-UHFFFAOYSA-N carbamothioylthiourea Chemical class NC(=S)NC(N)=S JIRRNZWTWJGJCT-UHFFFAOYSA-N 0.000 abstract 1
- YCLDXRHGQVDVJR-UHFFFAOYSA-N carbamothioylurea Chemical compound NC(=O)NC(N)=S YCLDXRHGQVDVJR-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
- QGBSISYHAICWAH-UHFFFAOYSA-N dicyandiamide Chemical compound NC(N)=NC#N QGBSISYHAICWAH-UHFFFAOYSA-N 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000003396 thiol group Chemical class [H]S* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/24—Y being a hetero atom
- C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19702009743 DE2009743A1 (de) | 1970-03-03 | 1970-03-03 | Substituierte Biguanide mit antihyperglykämischer Wirkung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1343831A true GB1343831A (en) | 1974-01-16 |
Family
ID=5763819
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2281571A Expired GB1343831A (en) | 1970-03-03 | 1971-04-19 | Pharmaceutical use of certain substituted biguanides |
Country Status (11)
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003086563A3 (en) * | 2002-04-11 | 2004-03-18 | Carbomer Inc | Diabetes imaging probes |
| CN110615886A (zh) * | 2019-09-05 | 2019-12-27 | 哈尔滨工程大学 | 一种双胍衍生物抗菌型环氧树脂固化剂及其制备方法 |
| CN115960018A (zh) * | 2022-12-19 | 2023-04-14 | 湖南岳靶生物医药有限公司 | 一种egfr抑制剂、组合物及其应用 |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2064664C (en) * | 1991-04-05 | 2000-01-11 | Hiroshi Ishikawa | Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives |
| DE122010000020I1 (de) | 1996-04-25 | 2010-07-08 | Prosidion Ltd | Verfahren zur Senkung des Blutglukosespiegels in Säugern |
| DE19828113A1 (de) | 1998-06-24 | 2000-01-05 | Probiodrug Ges Fuer Arzneim | Prodrugs von Inhibitoren der Dipeptidyl Peptidase IV |
| DE19828114A1 (de) | 1998-06-24 | 2000-01-27 | Probiodrug Ges Fuer Arzneim | Produgs instabiler Inhibitoren der Dipeptidyl Peptidase IV |
| DE19834591A1 (de) | 1998-07-31 | 2000-02-03 | Probiodrug Ges Fuer Arzneim | Verfahren zur Steigerung des Blutglukosespiegels in Säugern |
| DE19926233C1 (de) | 1999-06-10 | 2000-10-19 | Probiodrug Ges Fuer Arzneim | Verfahren zur Herstellung von Thiazolidin |
| KR20030019337A (ko) | 2000-03-31 | 2003-03-06 | 프로비오드룩 아게 | 진성 당뇨병에서 도세포 신호전달을 개선시키고 진성당뇨병을 예방하는 방법 |
| US7132104B1 (en) | 2000-10-27 | 2006-11-07 | Probiodrug Ag | Modulation of central nervous system (CNS) dipeptidyl peptidase IV (DPIV) -like activity for the treatment of neurological and neuropsychological disorders |
| FR2822464B1 (fr) | 2001-03-21 | 2004-08-06 | Lipha | Derives biguanides et leurs applications en therapeutique |
| US6890905B2 (en) | 2001-04-02 | 2005-05-10 | Prosidion Limited | Methods for improving islet signaling in diabetes mellitus and for its prevention |
| US20030130199A1 (en) | 2001-06-27 | 2003-07-10 | Von Hoersten Stephan | Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents |
| DE10150203A1 (de) | 2001-10-12 | 2003-04-17 | Probiodrug Ag | Peptidylketone als Inhibitoren der DPIV |
| US7368421B2 (en) | 2001-06-27 | 2008-05-06 | Probiodrug Ag | Use of dipeptidyl peptidase IV inhibitors in the treatment of multiple sclerosis |
| US6844316B2 (en) | 2001-09-06 | 2005-01-18 | Probiodrug Ag | Inhibitors of dipeptidyl peptidase I |
| MXPA04008278A (es) | 2002-02-28 | 2005-09-20 | Prosidion Ltd | Inhibidores de dipeptidil peptidasa iv a base de glutaminil. |
| JP4806628B2 (ja) | 2003-05-05 | 2011-11-02 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤 |
| KR20060009902A (ko) | 2003-05-05 | 2006-02-01 | 프로비오드룩 아게 | 글루타미닐 및 글루타메이트 사이클라제의 이펙터의 용도 |
| CA2554809C (en) | 2004-02-05 | 2014-04-29 | Probiodrug Ag | Novel n-alkyl thiourea- and thioamide-substituted imidazolyl inhibitors of glutaminyl cyclase |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR940304A (fr) * | 1946-01-07 | 1948-12-09 | Ici Ltd | Procédé de fabrication de dérivés de biguanides |
| FR1053761A (fr) * | 1949-01-31 | 1954-02-04 | Ici Ltd | Fabrication de dérivés de la biguanide |
| NL273482A (enrdf_load_stackoverflow) * | 1961-01-18 | |||
| FR6786M (enrdf_load_stackoverflow) * | 1967-08-10 | 1969-03-17 |
-
1970
- 1970-03-03 DE DE19702009743 patent/DE2009743A1/de active Pending
-
1971
- 1971-02-10 CH CH1459473A patent/CH564526A5/xx not_active IP Right Cessation
- 1971-02-10 CH CH197171A patent/CH553756A/xx not_active IP Right Cessation
- 1971-02-23 IE IE227/71A patent/IE34966B1/xx unknown
- 1971-02-23 IL IL7136271A patent/IL36271A0/xx unknown
- 1971-02-26 ZA ZA711269A patent/ZA711269B/xx unknown
- 1971-02-26 NL NL7102612A patent/NL7102612A/xx unknown
- 1971-03-02 AT AT176071A patent/AT302350B/de not_active IP Right Cessation
- 1971-03-03 BE BE763725A patent/BE763725A/xx unknown
- 1971-03-03 FR FR7107367A patent/FR2085665B1/fr not_active Expired
- 1971-03-03 ES ES388863A patent/ES388863A1/es not_active Expired
- 1971-04-19 GB GB2281571A patent/GB1343831A/en not_active Expired
- 1971-05-27 ES ES391629A patent/ES391629A1/es not_active Expired
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003086563A3 (en) * | 2002-04-11 | 2004-03-18 | Carbomer Inc | Diabetes imaging probes |
| US6911457B2 (en) | 2002-04-11 | 2005-06-28 | Carbomer, Inc. | Diabetes imaging probes |
| CN110615886A (zh) * | 2019-09-05 | 2019-12-27 | 哈尔滨工程大学 | 一种双胍衍生物抗菌型环氧树脂固化剂及其制备方法 |
| CN115960018A (zh) * | 2022-12-19 | 2023-04-14 | 湖南岳靶生物医药有限公司 | 一种egfr抑制剂、组合物及其应用 |
| CN115960018B (zh) * | 2022-12-19 | 2024-01-05 | 湖南岳靶生物医药有限公司 | 一种egfr抑制剂、组合物及其应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| NL7102612A (enrdf_load_stackoverflow) | 1971-09-07 |
| IE34966B1 (en) | 1975-10-01 |
| ES388863A1 (es) | 1973-06-01 |
| DE2009743A1 (de) | 1971-09-16 |
| AT302350B (de) | 1972-10-10 |
| ES391629A1 (es) | 1974-09-16 |
| IE34966L (en) | 1971-09-03 |
| IL36271A0 (en) | 1971-04-28 |
| ZA711269B (en) | 1971-11-24 |
| FR2085665B1 (enrdf_load_stackoverflow) | 1974-08-30 |
| CH564526A5 (enrdf_load_stackoverflow) | 1975-07-31 |
| FR2085665A1 (enrdf_load_stackoverflow) | 1971-12-31 |
| CH553756A (de) | 1974-09-13 |
| BE763725A (enrdf_load_stackoverflow) | 1971-09-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1343831A (en) | Pharmaceutical use of certain substituted biguanides | |
| GB1290388A (enrdf_load_stackoverflow) | ||
| GB1131191A (en) | New imidazole derivatives, their preparation and use | |
| GB1267324A (en) | s-TRIAZINE DERIVATIVES | |
| GB1264011A (en) | Fungicides | |
| GB1292410A (en) | Thienobenzothiazepine derivatives | |
| GB1433916A (en) | Thiophosphoric acid amides as nematocides insecticides and acaricides | |
| GB1276277A (en) | 2-chloroethane-(thiono)-phosphonic acid amido compounds, processes for their preparation, and their use for the regulation of plant growth | |
| ES373909A1 (es) | Procedimiento para la preparacion de quinazolinas. | |
| GB1305725A (enrdf_load_stackoverflow) | ||
| GB1168801A (en) | Quinoline Derivatives | |
| IE35223B1 (en) | Bis-basic ethers of 2,6- and 2,7-dihydroxyanthraquinones | |
| GB1186911A (en) | Novel Phosphorus-Containing 2-Imino-1,3-Dithioles | |
| GB1388402A (en) | Phosphorous containing pyrimidine derivatives and pesticidal com- positions thereof | |
| GB1368053A (en) | 3,4-dihydro-4-oxo-quinazolino/thiono/-phosphoric/phosphonic/-acid esters and esteramides process for their production and their use as insecticides or acaricides | |
| GB1182151A (en) | Bioactive Sulfones | |
| GB1227936A (enrdf_load_stackoverflow) | ||
| IE38725B1 (en) | Pyrimidopyrimidines | |
| GB1263395A (en) | Phloroglucic acid derivatives | |
| GB1434764A (en) | Pesticidal phosphorus-containing pyrimidine derivative | |
| GB1362389A (en) | Pharmaceutical preparations containing certain guanidine compounds | |
| GB1272081A (en) | Benzodiazocines | |
| GB1337527A (en) | Dithiophosphoric acid ester amides and their use as insecticides acaricides and nematocides | |
| GB1260145A (en) | Nitrothiophene derivatives | |
| GB1171208A (en) | (N-Nitrosoamino)-Guanidines |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |