GB1334705A - Pharmaceutical compositions containing kynurenic acid derivatives - Google Patents

Pharmaceutical compositions containing kynurenic acid derivatives

Info

Publication number
GB1334705A
GB1334705A GB1334705DA GB1334705A GB 1334705 A GB1334705 A GB 1334705A GB 1334705D A GB1334705D A GB 1334705DA GB 1334705 A GB1334705 A GB 1334705A
Authority
GB
United Kingdom
Prior art keywords
ester
pharmaceutical compositions
compositions containing
acid derivatives
alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of GB1334705A publication Critical patent/GB1334705A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/10—Aza-phenanthrenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB1334705D 1970-06-19 1970-06-19 Pharmaceutical compositions containing kynurenic acid derivatives Expired GB1334705A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2990570 1970-06-19

Publications (1)

Publication Number Publication Date
GB1334705A true GB1334705A (en) 1973-10-24

Family

ID=10299112

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1334705D Expired GB1334705A (en) 1970-06-19 1970-06-19 Pharmaceutical compositions containing kynurenic acid derivatives

Country Status (3)

Country Link
DE (1) DE2130408A1 (enExample)
FR (1) FR2100798B1 (enExample)
GB (1) GB1334705A (enExample)

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4128649A (en) 1977-06-29 1978-12-05 Sandoz, Inc. 4-Hydroxy-pyrido[2,3-b]pyridine-2(1H)-one-3-carboxylic acids and esters
US4273930A (en) * 1977-06-20 1981-06-16 Sandoz, Inc. 4-Hydroxy-2-quinolinone-3-carboxylic acid esters
US4281131A (en) 1977-06-20 1981-07-28 Sandoz, Inc. 4-Hydroxy-2-quinolinone-3-carboxylic acids and salts thereof
US4476132A (en) * 1981-03-24 1984-10-09 Ciba-Geigy Corporation Acylquinolinone derivatives, and antiallergic preparations and methods of inhibiting allergic reactions using them
EP0303387A1 (en) * 1987-08-12 1989-02-15 Merck Sharp & Dohme Ltd. Kynurenic acid derivatives useful in the treatment of neurodegenerative disorders
EP0339485A1 (en) * 1988-04-26 1989-11-02 The Du Pont Merck Pharmaceutical Company 4-Quinoline carboxylic acid derivatives useful as immunosuppressive agents
US4963566A (en) * 1986-03-28 1990-10-16 Otsuka Pharmaceutical Co., Ltd. Benzimidazolyl-sulfinyl-tetrahydroquinolines
US5204329A (en) * 1990-06-11 1993-04-20 Du Pont Merck Pharmaceutical Company Treatment of organ transplantation rejection
US5270309A (en) * 1987-08-12 1993-12-14 Merck Sharp & Dohme Limited Kynurenic acid derivatives useful in the treatment of neurodegenerative disorders
US6861424B2 (en) 2001-06-06 2005-03-01 Schering Aktiengesellschaft Platelet adenosine diphosphate receptor antagonists
US7056923B2 (en) 2002-12-11 2006-06-06 Schering Aktiengesellschaft Platelet adenosine diphosphate receptor antagonists
WO2010128345A1 (en) * 2009-05-05 2010-11-11 Szegedi Tudományegyetem Kynurenic acid analogues, pharmaceutical compositions containing same and use of said compounds for the treatment of headache
EP1851739A4 (en) * 2004-12-29 2012-08-29 Naturon Inc PHARMACEUTICAL XANTHANIC ACID DERIVATIVE COMPOSITIONS AND RELATED METHODS

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3865831A (en) * 1972-06-09 1975-02-11 Upjohn Co 1,1{40 ,4,4{40 -tetrahydro-4,4{40 -dioxo(6,6{40 biquinoline)-2,2{40 -dicarboxylates
FR2827599A1 (fr) * 2001-07-20 2003-01-24 Neuro3D Composes derives de quinoleine et quinoxaline,preparation et utilisations

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1207771A (en) * 1968-03-18 1970-10-07 Warner Lambert Pharmaceutical Anti-virally active quinoline derivatives

Cited By (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4273930A (en) * 1977-06-20 1981-06-16 Sandoz, Inc. 4-Hydroxy-2-quinolinone-3-carboxylic acid esters
US4281131A (en) 1977-06-20 1981-07-28 Sandoz, Inc. 4-Hydroxy-2-quinolinone-3-carboxylic acids and salts thereof
US4128649A (en) 1977-06-29 1978-12-05 Sandoz, Inc. 4-Hydroxy-pyrido[2,3-b]pyridine-2(1H)-one-3-carboxylic acids and esters
US4476132A (en) * 1981-03-24 1984-10-09 Ciba-Geigy Corporation Acylquinolinone derivatives, and antiallergic preparations and methods of inhibiting allergic reactions using them
EP0062001B1 (de) * 1981-03-24 1987-05-27 Ciba-Geigy Ag Acyl-chinolinonderivate, Verfahren zu ihrer Herstellung, diese enthaltende pharmazeutische Präparate und ihre Verwendung
US4963566A (en) * 1986-03-28 1990-10-16 Otsuka Pharmaceutical Co., Ltd. Benzimidazolyl-sulfinyl-tetrahydroquinolines
EP0303387A1 (en) * 1987-08-12 1989-02-15 Merck Sharp & Dohme Ltd. Kynurenic acid derivatives useful in the treatment of neurodegenerative disorders
US5270309A (en) * 1987-08-12 1993-12-14 Merck Sharp & Dohme Limited Kynurenic acid derivatives useful in the treatment of neurodegenerative disorders
EP0339485A1 (en) * 1988-04-26 1989-11-02 The Du Pont Merck Pharmaceutical Company 4-Quinoline carboxylic acid derivatives useful as immunosuppressive agents
US5204329A (en) * 1990-06-11 1993-04-20 Du Pont Merck Pharmaceutical Company Treatment of organ transplantation rejection
US6861424B2 (en) 2001-06-06 2005-03-01 Schering Aktiengesellschaft Platelet adenosine diphosphate receptor antagonists
US6995156B2 (en) 2001-06-06 2006-02-07 Schering Aktiengesellschaft Platelet adenosine diphosphate receptor antagonists
US7026323B2 (en) 2001-06-06 2006-04-11 Schering Aktiengesellschaft Platelet adenosine diphosphate receptor antagonists
US7176207B2 (en) 2001-06-06 2007-02-13 Schering Aktiengesellschaft Platelet adenosine diphosphate receptor antagonists
US7056923B2 (en) 2002-12-11 2006-06-06 Schering Aktiengesellschaft Platelet adenosine diphosphate receptor antagonists
US7084142B2 (en) 2002-12-11 2006-08-01 Schering Aktiengesellschaft Platelet adenosine diphosphate receptor antagonists
EP1851739A4 (en) * 2004-12-29 2012-08-29 Naturon Inc PHARMACEUTICAL XANTHANIC ACID DERIVATIVE COMPOSITIONS AND RELATED METHODS
US8361734B2 (en) 2004-12-29 2013-01-29 Naturon, Inc. Xanthurenic acid derivative pharmaceutical compositions and methods related thereto
US8697674B2 (en) 2004-12-29 2014-04-15 Naturon, Inc. Xanthurenic acid derivative pharmaceutical compositions and methods related thereto
US10370335B2 (en) 2004-12-29 2019-08-06 Naturon, Inc. Xanthurenic acid derivative pharmaceutical compositions and methods related thereto
WO2010128345A1 (en) * 2009-05-05 2010-11-11 Szegedi Tudományegyetem Kynurenic acid analogues, pharmaceutical compositions containing same and use of said compounds for the treatment of headache

Also Published As

Publication number Publication date
FR2100798B1 (enExample) 1975-10-10
FR2100798A1 (enExample) 1972-03-24
DE2130408A1 (de) 1971-12-23

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees