GB1317210A - Reduction of thebaine - Google Patents
Reduction of thebaineInfo
- Publication number
- GB1317210A GB1317210A GB5892670A GB1317210DA GB1317210A GB 1317210 A GB1317210 A GB 1317210A GB 5892670 A GB5892670 A GB 5892670A GB 1317210D A GB1317210D A GB 1317210DA GB 1317210 A GB1317210 A GB 1317210A
- Authority
- GB
- United Kingdom
- Prior art keywords
- thebaine
- dihydrothebaine
- reduction
- dihydrocodeinone
- azodicarboxylate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- FQXXSQDCDRQNQE-UHFFFAOYSA-N markiertes Thebain Natural products COC1=CC=C2C(N(CC3)C)CC4=CC=C(OC)C5=C4C23C1O5 FQXXSQDCDRQNQE-UHFFFAOYSA-N 0.000 title abstract 2
- FQXXSQDCDRQNQE-VMDGZTHMSA-N thebaine Chemical compound C([C@@H](N(CC1)C)C2=CC=C3OC)C4=CC=C(OC)C5=C4[C@@]21[C@H]3O5 FQXXSQDCDRQNQE-VMDGZTHMSA-N 0.000 title abstract 2
- 229930003945 thebaine Natural products 0.000 title abstract 2
- XJZOLKDBHJPTAT-ATNYCFDYSA-N (4r,4ar,7ar,12bs)-7,9-dimethoxy-3-methyl-2,4,4a,5,7a,13-hexahydro-1h-4,12-methanobenzofuro[3,2-e]isoquinoline Chemical compound C([C@@H](N(CC1)C)[C@@H]2CC=C3OC)C4=CC=C(OC)C5=C4[C@@]21[C@H]3O5 XJZOLKDBHJPTAT-ATNYCFDYSA-N 0.000 abstract 2
- -1 aralkyl sulphonic acid Chemical compound 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 229940042795 hydrazides for tuberculosis treatment Drugs 0.000 abstract 1
- LLPOLZWFYMWNKH-CMKMFDCUSA-N hydrocodone Chemical compound C([C@H]1[C@H](N(CC[C@@]112)C)C3)CC(=O)[C@@H]1OC1=C2C3=CC=C1OC LLPOLZWFYMWNKH-CMKMFDCUSA-N 0.000 abstract 1
- 229960000240 hydrocodone Drugs 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5892670 | 1970-12-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1317210A true GB1317210A (en) | 1973-05-16 |
Family
ID=10482707
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5892670A Expired GB1317210A (en) | 1970-12-11 | 1970-12-11 | Reduction of thebaine |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US3812132A (enExample) |
| JP (1) | JPS5511678B1 (enExample) |
| AU (1) | AU459401B2 (enExample) |
| BE (1) | BE776304A (enExample) |
| CA (1) | CA958412A (enExample) |
| CH (1) | CH556340A (enExample) |
| CS (1) | CS176251B2 (enExample) |
| DE (1) | DE2159348A1 (enExample) |
| DK (1) | DK139974B (enExample) |
| FR (1) | FR2117924B1 (enExample) |
| GB (1) | GB1317210A (enExample) |
| HU (1) | HU164465B (enExample) |
| IL (1) | IL38268A (enExample) |
| NL (1) | NL175622C (enExample) |
| PL (1) | PL81441B1 (enExample) |
| SE (1) | SE388422B (enExample) |
| YU (1) | YU39064B (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59142770A (ja) * | 1983-02-02 | 1984-08-16 | Trio Kenwood Corp | カセツトテ−プレコ−ダの駆動機構 |
| WO2006005112A1 (en) * | 2004-07-09 | 2006-01-19 | Tasmanian Alkaloids Pty Ltd | Process for the synthesis of hydromorphone |
| US20080125592A1 (en) * | 2006-10-17 | 2008-05-29 | Penick Corporation | Process for preparing oxymorphone, naltrexone, and buprenorphine |
| AU2007313103C1 (en) | 2006-10-17 | 2014-01-30 | Penick Corporation | Process for preparing oxymorphone |
| CA2674915C (en) | 2006-10-17 | 2015-06-30 | Penick Corporation | Process for preparing oxymorphone |
| GB0624880D0 (en) * | 2006-12-14 | 2007-01-24 | Johnson Matthey Plc | Improved method for making analgesics |
| US9131649B2 (en) | 2008-03-07 | 2015-09-15 | Tasmanian Alkaloids Pty. Ltd | Papaver somniferum strain with high concentration of thebaine |
| US8541647B2 (en) | 2008-05-29 | 2013-09-24 | Tasmania Alkaloids Pty, Ltd. | Papaver somniferum with high concentration of codeine |
| EP2480555B1 (en) | 2009-09-22 | 2015-11-11 | Mallinckrodt LLC | Methods for producing hydrocodone, hydromorphone or a derivative thereof |
| WO2011154826A1 (en) | 2010-06-11 | 2011-12-15 | Rhodes Technologies | Process for n-dealkylation of tertiary amines |
| ES2645725T3 (es) | 2010-06-11 | 2017-12-07 | Rhodes Technologies | Procesos catalizados por metales de transición para la preparación de compuestos de N-alilo y uso de los mismos |
| CA2919602C (en) | 2013-08-02 | 2018-03-13 | Johnson Matthey Public Limited Company | Process for the preparation of oxymorphone |
| US9273060B2 (en) | 2014-03-05 | 2016-03-01 | Johnson Matthey Public Limited Company | Processes for making hydrocodone, hydromorphone and their derivatives |
| WO2015134003A1 (en) | 2014-03-05 | 2015-09-11 | Johnson Matthey Public Limited Company | Processes for making hydrocodone, hydromorphone and their derivatives |
| US10155771B2 (en) | 2015-11-04 | 2018-12-18 | Noramco, Inc. | Selective reduction of morphinan alkaloids |
-
1970
- 1970-12-11 GB GB5892670A patent/GB1317210A/en not_active Expired
-
1971
- 1971-11-24 PL PL1971151754A patent/PL81441B1/pl unknown
- 1971-11-30 CA CA128,915A patent/CA958412A/en not_active Expired
- 1971-11-30 IL IL38268A patent/IL38268A/en unknown
- 1971-11-30 DE DE19712159348 patent/DE2159348A1/de not_active Withdrawn
- 1971-12-02 US US00204298A patent/US3812132A/en not_active Expired - Lifetime
- 1971-12-03 AU AU36469/71A patent/AU459401B2/en not_active Expired
- 1971-12-06 BE BE776304A patent/BE776304A/xx not_active IP Right Cessation
- 1971-12-07 JP JP9899371A patent/JPS5511678B1/ja active Pending
- 1971-12-07 FR FR7143867A patent/FR2117924B1/fr not_active Expired
- 1971-12-09 CS CS8571A patent/CS176251B2/cs unknown
- 1971-12-09 YU YU03086/71A patent/YU39064B/xx unknown
- 1971-12-09 DK DK603371AA patent/DK139974B/da unknown
- 1971-12-10 CH CH1811571A patent/CH556340A/xx not_active IP Right Cessation
- 1971-12-10 SE SE7115886A patent/SE388422B/xx unknown
- 1971-12-10 HU HUMA2294A patent/HU164465B/hu unknown
- 1971-12-13 NL NLAANVRAGE7117082,A patent/NL175622C/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL38268A (en) | 1974-11-29 |
| AU3646971A (en) | 1973-06-07 |
| PL81441B1 (enExample) | 1975-08-30 |
| CH556340A (de) | 1974-11-29 |
| IL38268A0 (en) | 1972-01-27 |
| BE776304A (fr) | 1972-06-06 |
| DK139974C (enExample) | 1979-12-10 |
| FR2117924A1 (enExample) | 1972-07-28 |
| DE2159348A1 (de) | 1972-06-15 |
| SE388422B (sv) | 1976-10-04 |
| NL175622C (nl) | 1984-12-03 |
| CS176251B2 (enExample) | 1977-06-30 |
| JPS5511678B1 (enExample) | 1980-03-26 |
| AU459401B2 (en) | 1975-03-27 |
| DK139974B (da) | 1979-05-28 |
| US3812132A (en) | 1974-05-21 |
| NL7117082A (enExample) | 1972-06-13 |
| YU39064B (en) | 1984-04-30 |
| HU164465B (enExample) | 1974-02-28 |
| NL175622B (nl) | 1984-07-02 |
| CA958412A (en) | 1974-11-26 |
| FR2117924B1 (enExample) | 1975-02-07 |
| YU308671A (en) | 1982-06-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1317210A (en) | Reduction of thebaine | |
| GB1132083A (en) | A novel thymine derivative and a process for the preparation thereof | |
| GB1417869A (en) | Controlled release door holder | |
| GB1374979A (en) | 3,5-dioxopiperazine derivatives | |
| CA987675A (en) | Alkyl or halo substituted tetrahalofluorans | |
| CA976963A (en) | Adducts of bis-(2-pyridyl-1-oxide) disulfide with alkaline earth metal salts | |
| GB1168455A (en) | Preparation and use of Substituted Fluoran Derivatives | |
| GB1295685A (enExample) | ||
| GB1139002A (en) | Bromophenol derivatives | |
| CA925870A (en) | Basic-substituted alkyl theophyllines with branched alkyl group | |
| ES348122A1 (es) | Procedimiento para la preparacion de acido 4,4-diamino-1,1-diantraquinonil-3,3-disulfonico. | |
| GB1252937A (enExample) | ||
| GB1253549A (en) | Aminoguanidine derivatives | |
| ES391857A1 (es) | Procedimiento para la preparacion de nuevos derivados de la19-nor-androstenolona. | |
| GB1244145A (en) | Lumilysergic acid derivatives | |
| GB1184312A (en) | Process for the Manufacture of Propanesultone | |
| GB1278679A (en) | Production of 2-alkyl-4-nitroimidazoles | |
| GB1287853A (enExample) | ||
| ES354006A1 (es) | Un procedimiento de preparacion de derivados del acido in- dolilacetico. | |
| ES370442A1 (es) | Un procedimiento para la preparacion de compuestos deriva- dos de alfa-aminopenicilinas. | |
| FR2054955A5 (en) | Antimicrobial n-subst 6,7-methylenedioxy-4- - quinolone derivs prepn | |
| GB1202626A (en) | New hydrocortisone derivatives and process | |
| GB1149256A (en) | Novel 19-nor-testosterone esters | |
| FR2106830A5 (en) | 1-phenyl-2-styryl pyrazolin-5-one-3-yl salicylates - with antirheumatic activity | |
| NL7010194A (en) | Antimicrobial n-subst 6,7-methylenedioxy-4- - quinolone derivs prepn |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |