GB1313977A - Ester derivatives of tetrahydrocannabinols - Google Patents

Ester derivatives of tetrahydrocannabinols

Info

Publication number
GB1313977A
GB1313977A GB2151271A GB2151271A GB1313977A GB 1313977 A GB1313977 A GB 1313977A GB 2151271 A GB2151271 A GB 2151271A GB 2151271 A GB2151271 A GB 2151271A GB 1313977 A GB1313977 A GB 1313977A
Authority
GB
United Kingdom
Prior art keywords
alkyl
compounds
tetrahydrocannabinols
ester derivatives
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2151271A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arthur D Little Inc
Original Assignee
Arthur D Little Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arthur D Little Inc filed Critical Arthur D Little Inc
Publication of GB1313977A publication Critical patent/GB1313977A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1313977 Amino-esters derived from dibenzo- [b,d]pyran ARTHUR D LITTLE Inc 19 April 1971 [13 Feb 1970] 21512/71 Heading C2C The invention comprises compounds of formula and their acid-addition and quaternary salts, wherein n is 0-6; R 1 , R 2 , R 3 and R 4 are each C 1-6 alkyl; R 5 is C 1-20 alkyl or cycloalkyl (C 3-8 )- C 1-6 -alkyl; and R 6 is H or C 1-6 -alkyl. These compounds are prepared by reacting together, in presence of a condensing agent, the corresponding phenol and carboxylic acid. Therapeutic compositions for oral or parenteral administration comprise compounds of the above formula, which have C.N.S. activity.
GB2151271A 1970-02-13 1971-04-19 Ester derivatives of tetrahydrocannabinols Expired GB1313977A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1129770A 1970-02-13 1970-02-13

Publications (1)

Publication Number Publication Date
GB1313977A true GB1313977A (en) 1973-04-18

Family

ID=21749751

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2151271A Expired GB1313977A (en) 1970-02-13 1971-04-19 Ester derivatives of tetrahydrocannabinols

Country Status (5)

Country Link
JP (1) JPS5518709B2 (en)
CA (1) CA967971A (en)
DE (1) DE2106705A1 (en)
FR (1) FR2081512B1 (en)
GB (1) GB1313977A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2352497A2 (en) * 2008-10-31 2011-08-10 Elsohly Laboratories, Incorporated Compositions containing delta-9-thc-amino acid esters and process of preparation
US9695143B2 (en) 2007-11-30 2017-07-04 Zynerba Pharmaceuticals, Inc. Prodrugs of tetrahydrocannabinol, compositions comprising prodrugs of tetrahydrocannabinol and methods of using the same

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4133819A (en) * 1977-06-17 1979-01-09 Pfizer Inc. Hexahydro-1-hydroxy-9-hydroxymethyl-3-substituted-6H-dibenzo[b,d]pyrans as analgesic agents
WO2006007734A1 (en) * 2004-07-19 2006-01-26 Cilag Ltd. Method for obtaining pure tetrahydrocannabinol
KR20200070764A (en) * 2018-12-10 2020-06-18 메디칸(주) Method and apparatus for controlling the size of hyaluronic acid filler suitable for human body

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB564827A (en) * 1941-07-09 1944-10-16 Roger Adams Process of preparing a dibenzopyran derivative having marihuana activity
US3325490A (en) * 1965-02-23 1967-06-13 Rexall Drug Chemical Substituted 1-hydroxydibenzopyrans
US3388136A (en) * 1966-01-11 1968-06-11 Edward C. Taylor Dibenzo [b, d] pyrans and process
US3507885A (en) * 1966-03-25 1970-04-21 Hoffmann La Roche 3-alkyl-6h-dibenzo(b,d)pyrans

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9695143B2 (en) 2007-11-30 2017-07-04 Zynerba Pharmaceuticals, Inc. Prodrugs of tetrahydrocannabinol, compositions comprising prodrugs of tetrahydrocannabinol and methods of using the same
US9957246B2 (en) 2007-11-30 2018-05-01 Zynerba Pharmaceuticals, Inc. Prodrugs of tetrahydrocannabinol, compositions comprising prodrugs of tetrahydrocannabinol and methods of using the same
EP2352497A2 (en) * 2008-10-31 2011-08-10 Elsohly Laboratories, Incorporated Compositions containing delta-9-thc-amino acid esters and process of preparation
EP2352497A4 (en) * 2008-10-31 2012-08-01 Elsohly Lab Inc Compositions containing delta-9-thc-amino acid esters and process of preparation
US8809261B2 (en) 2008-10-31 2014-08-19 Elsohly Laboratories, Incorporated Compositions containing delta-9-THC-amino acid esters and process of preparation

Also Published As

Publication number Publication date
DE2106705A1 (en) 1971-08-26
FR2081512A1 (en) 1971-12-03
JPS461025A (en) 1971-09-09
CA967971A (en) 1975-05-20
JPS5518709B2 (en) 1980-05-21
FR2081512B1 (en) 1975-06-06

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee