GB1312712A - Method of determining bilirubin - Google Patents

Method of determining bilirubin

Info

Publication number
GB1312712A
GB1312712A GB1643170A GB1643170A GB1312712A GB 1312712 A GB1312712 A GB 1312712A GB 1643170 A GB1643170 A GB 1643170A GB 1643170 A GB1643170 A GB 1643170A GB 1312712 A GB1312712 A GB 1312712A
Authority
GB
United Kingdom
Prior art keywords
bilirubin
colour
april
reacting
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1643170A
Inventor
Jerry W Denney
Larry W Denney
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
American Monitor Corp
Original Assignee
American Monitor Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Monitor Corp filed Critical American Monitor Corp
Publication of GB1312712A publication Critical patent/GB1312712A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/903—Diazo reactions
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555—Hetero-N
    • Y10T436/146666—Bile pigment

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

1312712 Determination of bilirubin AMERICAN MONITOR CORP 7 April 1970 [7 April 1969] 16431/70 Heading B1X Total and/or conjugated bilirubin are determined by a method comprising a) for conjugated bilirubin, reacting the sample with a diazo compound in acid solution to produce a colour, b) for total bilirubin, reacting the sample with a diazo compound in the presence of a catalyst, for example caffeine, to produce a colour, c) in each case, providing hydroxylamine in the reaction mixture, d) in each case, measuring the colour formed. The reaction mixtures after addition of hydroxylamine hydrochloride in step c are preferably made alkaline by addition of Fehling II solution (sodium potassium tartrate and NaOH). There is reference to use of urea or sodium benzoate as alternative catalysts.
GB1643170A 1969-04-07 1970-04-07 Method of determining bilirubin Expired GB1312712A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US814161A US3652222A (en) 1969-04-07 1969-04-07 Bilirubin assay

Publications (1)

Publication Number Publication Date
GB1312712A true GB1312712A (en) 1973-04-04

Family

ID=25214328

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1643170A Expired GB1312712A (en) 1969-04-07 1970-04-07 Method of determining bilirubin

Country Status (5)

Country Link
US (1) US3652222A (en)
JP (1) JPS515600B1 (en)
DE (1) DE2016555C3 (en)
FR (1) FR2043035A5 (en)
GB (1) GB1312712A (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2130559C3 (en) * 1971-06-19 1973-11-22 Boehringer Mannheim Gmbh, 6800 Mannheim Diagnostic means for the detection of urobihnogen
DE2229611C3 (en) * 1972-06-19 1980-07-17 Boehringer Mannheim Gmbh, 6800 Mannheim Diagnostic detection of urobilinogen bodies
DE2240357C2 (en) * 1972-08-17 1974-09-12 Boehringer Mannheim Gmbh, 6800 Mannheim Test paper for the detection of bilirubin in body fluids
DE2240471C3 (en) * 1972-08-17 1975-04-03 Boehringer Mannheim Gmbh, 6800 Mannheim Test paper for the detection of bilirubin in body fluids
DE2301687A1 (en) * 1973-01-13 1974-07-18 Boehringer Sohn Ingelheim METHOD FOR DETERMINING TOTAL BILIRUBIN IN BODY FLUIDS
FR2280082A1 (en) * 1974-07-25 1976-02-20 Reveilleau R Hydrazine-stabilized bilirubin colorimetric assay - by coupling of free or conjugated bilirubin with diazonium salts
US4078892A (en) * 1975-06-30 1978-03-14 Becton, Dickinson And Company Novel means and method for diagnostic quantitation of serum or plasma bilirubin
US4030885A (en) * 1975-09-11 1977-06-21 Sigma Chemical Company Bilirubin determination
US4115064A (en) * 1977-02-07 1978-09-19 Pierce Chemical Company Method for bilirubin determination
US4260579A (en) * 1979-05-10 1981-04-07 Miles Laboratories, Inc. Device and method for simulating bilirubin in urine
US4336157A (en) * 1980-06-27 1982-06-22 Baxter Travenol Laboratories, Inc. Process for reclaiming biliverdin-containing fluids
WO1995000843A1 (en) * 1993-06-18 1995-01-05 Synermed, Inc. Assay for total bilirubin
JP3091094B2 (en) * 1993-12-28 2000-09-25 ユニチカ株式会社 Reagent for direct bilirubin measurement
WO1996002841A1 (en) * 1994-07-14 1996-02-01 Abbott Laboratories Methods and reagents for cyanide-free determination of hemoglobin and leukocytes in whole blood
US5804405A (en) * 1996-11-27 1998-09-08 Research Corporation Technologies, Inc. Bilirubin detection
US6326208B1 (en) 1997-07-17 2001-12-04 Synermed International Inc. Assay for total and direct bilirubin
US20050266579A1 (en) * 2004-06-01 2005-12-01 Xihai Mu Assay system with in situ formation of diazo reagent
EP3555632B1 (en) * 2016-12-14 2021-03-10 Roche Diagnostics GmbH Determination of bilirubin in a sample

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3348920A (en) * 1964-02-25 1967-10-24 Dade Reagents Inc Reagent and method for the quantitative determination of bilirubin
US3511607A (en) * 1967-10-06 1970-05-12 Smithkline Corp Laboratory reagent for assay of total bilirubin

Also Published As

Publication number Publication date
DE2016555A1 (en) 1970-11-05
DE2016555B2 (en) 1979-02-01
DE2016555C3 (en) 1979-10-04
US3652222A (en) 1972-03-28
FR2043035A5 (en) 1971-02-12
JPS515600B1 (en) 1976-02-20

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee