GB1312205A - Method and composition for lowering blood pressure - Google Patents
Method and composition for lowering blood pressureInfo
- Publication number
- GB1312205A GB1312205A GB1832071A GB1832071A GB1312205A GB 1312205 A GB1312205 A GB 1312205A GB 1832071 A GB1832071 A GB 1832071A GB 1832071 A GB1832071 A GB 1832071A GB 1312205 A GB1312205 A GB 1312205A
- Authority
- GB
- United Kingdom
- Prior art keywords
- composition
- alkyl
- blood pressure
- lowering blood
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000036772 blood pressure Effects 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000001631 hypertensive effect Effects 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000003039 tetrahydroisoquinolinyl group Chemical class C1(NCCC2=CC=CC=C12)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7090070A | 1970-09-09 | 1970-09-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1312205A true GB1312205A (en) | 1973-04-04 |
Family
ID=22098044
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1832071A Expired GB1312205A (en) | 1970-09-09 | 1971-06-01 | Method and composition for lowering blood pressure |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS4824396B1 (enExample) |
| BE (1) | BE763149R (enExample) |
| CH (1) | CH550797A (enExample) |
| DE (1) | DE2101691A1 (enExample) |
| FR (1) | FR2106399B2 (enExample) |
| GB (1) | GB1312205A (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS50123994U (enExample) * | 1974-03-26 | 1975-10-09 | ||
| US20010016657A1 (en) * | 1997-03-18 | 2001-08-23 | Smithkline Beecham P.L.C. | Substituted isoquinoline derivatives and their use as anticonvulsants |
| JP2001521026A (ja) * | 1997-10-24 | 2001-11-06 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | 置換イソキノリン誘導体および抗痙攣薬としての使用 |
| ATE416168T1 (de) | 2002-02-15 | 2008-12-15 | Glaxo Group Ltd | Modulatoren des vanilloidrezeptors |
| SI2046787T1 (sl) | 2006-08-01 | 2011-07-29 | Glaxo Group Ltd | Pirazolo(3,4-b)piridinske spojine in njihova uporaba kot PDE4 inhibitorji |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3674791A (en) * | 1968-03-26 | 1972-07-04 | Marion Laboratories Inc | Benzamido 2 lower alkyl decahydroisoquinolines |
-
1970
- 1970-12-28 JP JP11953270A patent/JPS4824396B1/ja active Pending
-
1971
- 1971-01-15 DE DE19712101691 patent/DE2101691A1/de active Pending
- 1971-02-18 BE BE763149A patent/BE763149R/xx active
- 1971-05-17 CH CH732371A patent/CH550797A/xx not_active IP Right Cessation
- 1971-06-01 GB GB1832071A patent/GB1312205A/en not_active Expired
- 1971-09-08 FR FR7132410A patent/FR2106399B2/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2106399A2 (enExample) | 1972-05-05 |
| BE763149R (fr) | 1971-07-16 |
| CH550797A (de) | 1974-06-28 |
| FR2106399B2 (enExample) | 1974-10-18 |
| DE2101691A1 (de) | 1972-03-16 |
| JPS4824396B1 (enExample) | 1973-07-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |