GB1300516A - Pharmaceutical compositions with a vitamin a activity - Google Patents
Pharmaceutical compositions with a vitamin a activityInfo
- Publication number
- GB1300516A GB1300516A GB38977/71A GB3897771A GB1300516A GB 1300516 A GB1300516 A GB 1300516A GB 38977/71 A GB38977/71 A GB 38977/71A GB 3897771 A GB3897771 A GB 3897771A GB 1300516 A GB1300516 A GB 1300516A
- Authority
- GB
- United Kingdom
- Prior art keywords
- vitamin
- polyoxyethylene sorbitan
- activity
- pharmaceutical compositions
- aug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229940045997 vitamin a Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 3
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 abstract 2
- 239000002202 Polyethylene glycol Substances 0.000 abstract 2
- 229920001214 Polysorbate 60 Polymers 0.000 abstract 2
- 229920001223 polyethylene glycol Polymers 0.000 abstract 2
- URAYPUMNDPQOKB-UHFFFAOYSA-N triacetin Chemical compound CC(=O)OCC(OC(C)=O)COC(C)=O URAYPUMNDPQOKB-UHFFFAOYSA-N 0.000 abstract 2
- BXCRLBBIZJSWNS-UHFFFAOYSA-N 2-hydroxyethyl hexadecanoate Chemical compound CCCCCCCCCCCCCCCC(=O)OCCO BXCRLBBIZJSWNS-UHFFFAOYSA-N 0.000 abstract 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- NWGKJDSIEKMTRX-AAZCQSIUSA-N Sorbitan monooleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O NWGKJDSIEKMTRX-AAZCQSIUSA-N 0.000 abstract 1
- 229930003427 Vitamin E Natural products 0.000 abstract 1
- SFRPDSKECHTFQA-ONOWFSFQSA-N [(2e,4e,6e,8e)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenyl] propanoate Chemical compound CCC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SFRPDSKECHTFQA-ONOWFSFQSA-N 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 239000003995 emulsifying agent Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 abstract 1
- 235000013773 glyceryl triacetate Nutrition 0.000 abstract 1
- 239000001087 glyceryl triacetate Substances 0.000 abstract 1
- 229940087073 glycol palmitate Drugs 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 229920000136 polysorbate Polymers 0.000 abstract 1
- WBHHMMIMDMUBKC-QJWNTBNXSA-M ricinoleate Chemical compound CCCCCC[C@@H](O)C\C=C/CCCCCCCC([O-])=O WBHHMMIMDMUBKC-QJWNTBNXSA-M 0.000 abstract 1
- 229940066675 ricinoleate Drugs 0.000 abstract 1
- 229950004959 sorbitan oleate Drugs 0.000 abstract 1
- 229960002622 triacetin Drugs 0.000 abstract 1
- 229930003231 vitamin Natural products 0.000 abstract 1
- 229940088594 vitamin Drugs 0.000 abstract 1
- 235000013343 vitamin Nutrition 0.000 abstract 1
- 239000011782 vitamin Substances 0.000 abstract 1
- MECHNRXZTMCUDQ-RKHKHRCZSA-N vitamin D2 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)/C=C/[C@H](C)C(C)C)=C\C=C1\C[C@@H](O)CCC1=C MECHNRXZTMCUDQ-RKHKHRCZSA-N 0.000 abstract 1
- 235000019165 vitamin E Nutrition 0.000 abstract 1
- 229940046009 vitamin E Drugs 0.000 abstract 1
- 239000011709 vitamin E Substances 0.000 abstract 1
- 150000003722 vitamin derivatives Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL7012460A NL7012460A (enrdf_load_stackoverflow) | 1970-08-22 | 1970-08-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1300516A true GB1300516A (en) | 1972-12-20 |
Family
ID=19810838
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB38977/71A Expired GB1300516A (en) | 1970-08-22 | 1971-08-19 | Pharmaceutical compositions with a vitamin a activity |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS5525162B1 (enrdf_load_stackoverflow) |
| AU (1) | AU465702B2 (enrdf_load_stackoverflow) |
| CA (1) | CA962192A (enrdf_load_stackoverflow) |
| DE (1) | DE2138586C2 (enrdf_load_stackoverflow) |
| ES (1) | ES394393A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2103451B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1300516A (enrdf_load_stackoverflow) |
| NL (1) | NL7012460A (enrdf_load_stackoverflow) |
| ZA (1) | ZA715471B (enrdf_load_stackoverflow) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4075333A (en) | 1975-02-14 | 1978-02-21 | Hoffmann-La Roche, Inc. | Stable injectable vitamin compositions |
| US6432445B1 (en) | 1999-05-28 | 2002-08-13 | Novartis Ag | Pharmaceutical capsules comprising a cyclosporin |
| EP3223795A4 (en) * | 2014-11-25 | 2018-07-25 | Kl-Kepong Oleomas Sdn Bhd | Formulation for effective tocotrienol delivery |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58208215A (ja) * | 1982-05-31 | 1983-12-03 | Sato Seiyaku Kk | 脂溶性ビタミン配合油溶組成物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1392487A (fr) * | 1963-09-19 | 1965-03-19 | Eastman Kodak Co | Préparation vitaminique insoluble dans l'eau anhydre et susceptible de dispersion dans l'eau |
| DE2019839A1 (de) * | 1969-04-28 | 1970-11-05 | Ferrosan As | Stabile,klare,wasserdispergierbare bzw.-verduennbare,Vitamin-A enthaltende Loesung und Verfahren zu ihrer Herstellung |
-
1970
- 1970-08-22 NL NL7012460A patent/NL7012460A/xx not_active Application Discontinuation
-
1971
- 1971-08-02 DE DE2138586A patent/DE2138586C2/de not_active Expired
- 1971-08-16 ZA ZA715471A patent/ZA715471B/xx unknown
- 1971-08-19 GB GB38977/71A patent/GB1300516A/en not_active Expired
- 1971-08-19 CA CA120,889A patent/CA962192A/en not_active Expired
- 1971-08-20 JP JP6306271A patent/JPS5525162B1/ja active Pending
- 1971-08-20 ES ES394393A patent/ES394393A1/es not_active Expired
- 1971-08-20 FR FR7130439A patent/FR2103451B1/fr not_active Expired
- 1971-08-20 AU AU32567/71A patent/AU465702B2/en not_active Expired
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4075333A (en) | 1975-02-14 | 1978-02-21 | Hoffmann-La Roche, Inc. | Stable injectable vitamin compositions |
| US6432445B1 (en) | 1999-05-28 | 2002-08-13 | Novartis Ag | Pharmaceutical capsules comprising a cyclosporin |
| US6767555B2 (en) | 1999-05-28 | 2004-07-27 | Novartis Ag | Pharmaceutical compositions |
| EP3223795A4 (en) * | 2014-11-25 | 2018-07-25 | Kl-Kepong Oleomas Sdn Bhd | Formulation for effective tocotrienol delivery |
| US10478417B2 (en) | 2014-11-25 | 2019-11-19 | Kl-Kepong Oleomas Sdn Bhd | Formulation for effective tocotrienol delivery |
| US10493055B2 (en) | 2014-11-25 | 2019-12-03 | Kl-Kepong Oleomas Sdn Bhd | Formulation for effective tocotrienol delivery |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2103451A1 (enrdf_load_stackoverflow) | 1972-04-14 |
| ZA715471B (en) | 1972-04-26 |
| ES394393A1 (es) | 1975-04-01 |
| FR2103451B1 (enrdf_load_stackoverflow) | 1974-09-06 |
| JPS5525162B1 (enrdf_load_stackoverflow) | 1980-07-04 |
| AU3256771A (en) | 1973-02-22 |
| DE2138586A1 (de) | 1972-02-24 |
| NL7012460A (enrdf_load_stackoverflow) | 1972-02-24 |
| DE2138586C2 (de) | 1985-02-28 |
| CA962192A (en) | 1975-02-04 |
| AU465702B2 (en) | 1975-10-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| 732 | Registration of transactions, instruments or events in the register (sect. 32/1977) | ||
| PCNP | Patent ceased through non-payment of renewal fee |