GB1295447A - - Google Patents
Info
- Publication number
- GB1295447A GB1295447A GB5608669A GB1295447DA GB1295447A GB 1295447 A GB1295447 A GB 1295447A GB 5608669 A GB5608669 A GB 5608669A GB 1295447D A GB1295447D A GB 1295447DA GB 1295447 A GB1295447 A GB 1295447A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- nov
- compositions
- treatment
- agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 238000011282 treatment Methods 0.000 abstract 2
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 208000020401 Depressive disease Diseases 0.000 abstract 1
- 229940123685 Monoamine oxidase inhibitor Drugs 0.000 abstract 1
- 239000000674 adrenergic antagonist Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 229940035678 anti-parkinson drug Drugs 0.000 abstract 1
- 229940125681 anticonvulsant agent Drugs 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 239000000939 antiparkinson agent Substances 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 239000002899 monoamine oxidase inhibitor Substances 0.000 abstract 1
- 150000002780 morpholines Chemical class 0.000 abstract 1
- 239000003176 neuroleptic agent Substances 0.000 abstract 1
- 229940053544 other antidepressants in atc Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 229940125723 sedative agent Drugs 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
- C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5608669 | 1969-11-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1295447A true GB1295447A (enExample) | 1972-11-08 |
Family
ID=10475688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5608669A Expired GB1295447A (enExample) | 1969-11-17 | 1969-11-17 |
Country Status (11)
| Country | Link |
|---|---|
| AT (1) | AT302341B (enExample) |
| BE (1) | BE759013R (enExample) |
| CA (1) | CA927831A (enExample) |
| DE (1) | DE2056589A1 (enExample) |
| ES (1) | ES385627A2 (enExample) |
| FR (1) | FR2073375B2 (enExample) |
| GB (1) | GB1295447A (enExample) |
| IE (1) | IE34714B1 (enExample) |
| NL (1) | NL7016833A (enExample) |
| SU (2) | SU422159A3 (enExample) |
| ZA (1) | ZA707662B (enExample) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5169974A (en) * | 1988-10-21 | 1992-12-08 | Imperial Chemical Industries Plc | Process for manufacturing aryloxyaldehydes |
| WO2004017977A3 (en) * | 2002-08-23 | 2004-04-01 | Lilly Co Eli | 2- (phenoxymethyl)- and 2- (phenylthiomethyl)-morpholine derivatives for use as selective norepinephrine reuptake inhibitors |
| US7294623B2 (en) | 2002-08-23 | 2007-11-13 | Eli Lilly And Company | Benzyl morpholine derivatives |
| US7354920B2 (en) | 2002-08-23 | 2008-04-08 | Eli Lilly And Company | Aryl and heteroaryl morpholine derivatives |
| JP2008526904A (ja) * | 2005-01-14 | 2008-07-24 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング | ヒドロキシフェノール誘導体、その調製方法、それらを含む医薬組成物、およびその治療的使用 |
| US7659394B2 (en) | 2004-04-30 | 2010-02-09 | Pfizer Inc | Substituted morpholine compounds for the treatment of central nervous system disorders |
| US8044052B2 (en) | 2006-10-18 | 2011-10-25 | Pfizer Inc. | Biaryl ether urea compounds |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2346340A2 (fr) * | 1975-01-29 | 1977-10-28 | Yamanouchi Pharma Co Ltd | Derives de l'(indenyloxymethyl)-2-morpholine |
| DE2530860C2 (de) * | 1975-07-10 | 1987-01-15 | Yoshitomi Pharmaceutical Industries, Ltd., Osaka | 2-[2-(2-Thenyl)-phenoxymethyl]-morpholin-Derivate |
| IL56369A (en) * | 1978-01-20 | 1984-05-31 | Erba Farmitalia | Alpha-phenoxybenzyl propanolamine derivatives,their preparation and pharmaceutical compositions comprising them |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1138405A (en) * | 1966-12-28 | 1969-01-01 | Ici Ltd | Morpholine derivatives |
-
0
- BE BE759013D patent/BE759013R/xx active
-
1969
- 1969-11-17 GB GB5608669A patent/GB1295447A/en not_active Expired
-
1970
- 1970-11-10 IE IE1428/70A patent/IE34714B1/xx unknown
- 1970-11-12 CA CA098017A patent/CA927831A/en not_active Expired
- 1970-11-12 ZA ZA707662A patent/ZA707662B/xx unknown
- 1970-11-17 NL NL7016833A patent/NL7016833A/xx unknown
- 1970-11-17 AT AT1036270A patent/AT302341B/de not_active IP Right Cessation
- 1970-11-17 SU SU1716174A patent/SU422159A3/ru active
- 1970-11-17 ES ES385627A patent/ES385627A2/es not_active Expired
- 1970-11-17 DE DE19702056589 patent/DE2056589A1/de active Pending
- 1970-11-17 FR FR7041208A patent/FR2073375B2/fr not_active Expired
- 1970-11-17 SU SU1494684A patent/SU373945A3/ru active
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5169974A (en) * | 1988-10-21 | 1992-12-08 | Imperial Chemical Industries Plc | Process for manufacturing aryloxyaldehydes |
| WO2004017977A3 (en) * | 2002-08-23 | 2004-04-01 | Lilly Co Eli | 2- (phenoxymethyl)- and 2- (phenylthiomethyl)-morpholine derivatives for use as selective norepinephrine reuptake inhibitors |
| US7294623B2 (en) | 2002-08-23 | 2007-11-13 | Eli Lilly And Company | Benzyl morpholine derivatives |
| US7354920B2 (en) | 2002-08-23 | 2008-04-08 | Eli Lilly And Company | Aryl and heteroaryl morpholine derivatives |
| US7384941B2 (en) | 2002-08-23 | 2008-06-10 | Eli Lilly And Company | 2-(phenoxymethyl)-and 2-(phenylthiomethyl)-morpholine derivatives for use as selective norepinephrine reuptake inhibitors |
| US7659394B2 (en) | 2004-04-30 | 2010-02-09 | Pfizer Inc | Substituted morpholine compounds for the treatment of central nervous system disorders |
| JP2008526904A (ja) * | 2005-01-14 | 2008-07-24 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング | ヒドロキシフェノール誘導体、その調製方法、それらを含む医薬組成物、およびその治療的使用 |
| US8044052B2 (en) | 2006-10-18 | 2011-10-25 | Pfizer Inc. | Biaryl ether urea compounds |
Also Published As
| Publication number | Publication date |
|---|---|
| IE34714L (en) | 1971-05-17 |
| ZA707662B (en) | 1971-08-25 |
| FR2073375A2 (enExample) | 1971-10-01 |
| DE2056589A1 (de) | 1971-05-27 |
| BE759013R (fr) | 1971-05-17 |
| AT302341B (de) | 1972-10-10 |
| SU422159A3 (ru) | 1974-03-30 |
| SU373945A3 (enExample) | 1973-03-12 |
| IE34714B1 (en) | 1975-07-23 |
| NL7016833A (enExample) | 1971-05-19 |
| FR2073375B2 (enExample) | 1974-10-11 |
| CA927831A (en) | 1973-06-05 |
| ES385627A2 (es) | 1973-05-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PE20 | Patent expired after termination of 20 years |