GB1279946A - N(6) aralkyl-adenosine derivatives - Google Patents

N(6) aralkyl-adenosine derivatives

Info

Publication number
GB1279946A
GB1279946A GB21877/71A GB2187771A GB1279946A GB 1279946 A GB1279946 A GB 1279946A GB 21877/71 A GB21877/71 A GB 21877/71A GB 2187771 A GB2187771 A GB 2187771A GB 1279946 A GB1279946 A GB 1279946A
Authority
GB
United Kingdom
Prior art keywords
hydroxyl groups
adenosine
aralkyl
protected hydroxyl
optionally
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB21877/71A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of GB1279946A publication Critical patent/GB1279946A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB21877/71A 1970-02-18 1971-04-19 N(6) aralkyl-adenosine derivatives Expired GB1279946A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702007273 DE2007273A1 (de) 1970-02-18 1970-02-18 N(6) Aralkyl adenosin Derivate und Verfahren zur Herstellung derselben

Publications (1)

Publication Number Publication Date
GB1279946A true GB1279946A (en) 1972-06-28

Family

ID=5762543

Family Applications (1)

Application Number Title Priority Date Filing Date
GB21877/71A Expired GB1279946A (en) 1970-02-18 1971-04-19 N(6) aralkyl-adenosine derivatives

Country Status (14)

Country Link
US (1) US3781273A (enExample)
JP (1) JPS5116440B1 (enExample)
AT (2) AT313483B (enExample)
CA (1) CA953714A (enExample)
CH (2) CH549596A (enExample)
DE (1) DE2007273A1 (enExample)
DK (1) DK123357B (enExample)
ES (1) ES388194A1 (enExample)
FR (1) FR2081524B1 (enExample)
GB (1) GB1279946A (enExample)
HU (1) HU162739B (enExample)
IL (1) IL36211A0 (enExample)
NL (1) NL7102026A (enExample)
ZA (1) ZA711030B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU582359B2 (en) * 1984-04-18 1989-03-23 Nelson Research & Development Company N-6 substituted adenosine derivatives as cardiac vasodilators
US5310731A (en) 1984-06-28 1994-05-10 Whitby Research, Inc. N-6 substituted-5'-(N-substitutedcarboxamido)adenosines as cardiac vasodilators and antihypertensive agents
WO1988003147A1 (en) * 1986-10-31 1988-05-05 Warner-Lambert Company Selected n6-substituted adenosines having selective a2 binding activity
US5066655A (en) * 1987-04-24 1991-11-19 Whitby Research, Inc. N6-substituted 9-methyladenines: a new class of adenosine receptor antagonists
US5565566A (en) * 1987-04-24 1996-10-15 Discovery Therapeutics, Inc. N6 -substituted 9-methyladenines: a new class of adenosine receptor antagonists
US5070877A (en) * 1988-08-11 1991-12-10 Medco Research, Inc. Novel method of myocardial imaging
US5030624A (en) * 1988-10-26 1991-07-09 G. D. Searle & Co. R-diastereomer of an N6 -[(2-hydroxypropyl)aryl]adenosine and its medicinal uses
US5032584A (en) * 1988-10-26 1991-07-16 G. D. Searle & Co. S-diastereomer of an n6 -((2-hydroxypropyl)aryl)adenosine and its medicinal uses
US6784165B1 (en) 1999-11-23 2004-08-31 Aderis Pharmaceuticals, Inc. Treatment of heart rhythm disturbances with N6-substituted-5′-(N-substituted) carboxamidoadenosines
CZ294538B6 (cs) * 2002-12-30 2005-01-12 Ústav Experimentální Botaniky Akademie Vědčeské Re Substituční deriváty N6-benzyladenosinu, způsob jejich přípravy, jejich použití pro přípravu léčiv, kosmetických přípravků a růstových regulátorů, farmaceutické přípravky, kosmetické přípravky a růstové regulátory tyto sloučeniny obsahující
US20050009776A1 (en) * 2003-04-24 2005-01-13 Aderis Pharmaceuticals, Inc. Method of treating atrial fibrillation or atrial flutter
WO2005025545A2 (en) * 2003-09-17 2005-03-24 Aderis Pharmaceuticals, Inc. Pharmaceutical formulation for controlled release of selodenoson

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2881164A (en) * 1955-07-18 1959-04-07 American Cyanamid Co Ribofuranosyl derivatives of 6-aralkylamino and 6-heterocyclicalkylaminopurines
US3506643A (en) * 1966-12-09 1970-04-14 Max Thiel N**6-aralkyl-adenosine derivatives

Also Published As

Publication number Publication date
AT313483B (de) 1974-02-25
US3781273A (en) 1973-12-25
ZA711030B (en) 1971-11-24
FR2081524A1 (enExample) 1971-12-03
CH549600A (de) 1974-05-31
JPS5116440B1 (enExample) 1976-05-24
DK123357B (da) 1972-06-12
NL7102026A (enExample) 1971-08-20
CH549596A (de) 1974-05-31
DE2007273A1 (de) 1971-08-26
FR2081524B1 (enExample) 1974-09-27
ES388194A1 (es) 1973-05-01
IL36211A0 (en) 1971-04-28
HU162739B (enExample) 1973-04-28
AT306251B (de) 1973-04-10
SU399134A3 (enExample) 1973-09-27
CA953714A (en) 1974-08-27

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee