GB1274779A - Improved process for the preparation of pure digoxin monomethyl ethers - Google Patents

Improved process for the preparation of pure digoxin monomethyl ethers

Info

Publication number
GB1274779A
GB1274779A GB57485/70A GB5748570A GB1274779A GB 1274779 A GB1274779 A GB 1274779A GB 57485/70 A GB57485/70 A GB 57485/70A GB 5748570 A GB5748570 A GB 5748570A GB 1274779 A GB1274779 A GB 1274779A
Authority
GB
United Kingdom
Prior art keywords
digoxin
preparation
improved process
monomethyl ethers
methyldigoxin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB57485/70A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19691961034 external-priority patent/DE1961034C/de
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of GB1274779A publication Critical patent/GB1274779A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J19/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 by a lactone ring
    • C07J19/005—Glycosides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Installation Of Indoor Wiring (AREA)
GB57485/70A 1969-12-05 1970-12-03 Improved process for the preparation of pure digoxin monomethyl ethers Expired GB1274779A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19691961034 DE1961034C (de) 1969-12-05 Verfahren zur Herstellung von reinen Digoxin-mono-methyläthern

Publications (1)

Publication Number Publication Date
GB1274779A true GB1274779A (en) 1972-05-17

Family

ID=5753066

Family Applications (1)

Application Number Title Priority Date Filing Date
GB57485/70A Expired GB1274779A (en) 1969-12-05 1970-12-03 Improved process for the preparation of pure digoxin monomethyl ethers

Country Status (21)

Country Link
US (1) US3712884A (enExample)
JP (1) JPS5028957B1 (enExample)
AT (1) AT302544B (enExample)
BE (1) BE759912A (enExample)
BG (1) BG18865A3 (enExample)
CH (1) CH537378A (enExample)
CS (2) CS155250B2 (enExample)
DK (2) DK123354B (enExample)
ES (1) ES386172A1 (enExample)
FI (2) FI47183C (enExample)
FR (1) FR2081328B1 (enExample)
GB (1) GB1274779A (enExample)
IE (1) IE34790B1 (enExample)
IL (1) IL35788A (enExample)
NL (1) NL166696C (enExample)
NO (1) NO131297C (enExample)
PL (1) PL81222B1 (enExample)
RO (1) RO58835A (enExample)
SE (1) SE356046B (enExample)
YU (1) YU34302B (enExample)
ZA (1) ZA708221B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4603196A (en) * 1983-04-27 1986-07-29 Chemie Linz Aktiengesellschaft Process for the preparation of β-methyldigoxin

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2233147A1 (de) * 1972-07-06 1974-01-24 Boehringer Mannheim Gmbh Dihydrodigoxin-derivate
YU39367B (en) * 1976-08-20 1984-10-31 Lek Tovarna Farmacevtskih Process for preparing beta-methyl-digoxine
DE3146899A1 (de) * 1981-11-26 1983-06-01 Boehringer Mannheim Gmbh, 6800 Mannheim Neue ketale von 3'''-dehydro-cardenolid-tridigitoxosiden, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US4546097A (en) * 1983-11-04 1985-10-08 The United States Of America As Represented By The Department Of Health And Human Services Saponin-based polyether polyols, pharmaceutical compositions and a method of using same

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1643665B1 (de) * 1967-09-20 1971-02-18 Boehringer Mannheim Gmbh Neue Digoxinaether und Verfahren zur Herstellung derselben

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4603196A (en) * 1983-04-27 1986-07-29 Chemie Linz Aktiengesellschaft Process for the preparation of β-methyldigoxin

Also Published As

Publication number Publication date
IE34790L (en) 1971-06-05
FR2081328A1 (enExample) 1971-12-03
IE34790B1 (en) 1975-08-20
DE1961034A1 (de) 1971-06-09
YU291770A (en) 1978-10-31
BE759912A (fr) 1971-06-04
CS155249B2 (enExample) 1974-05-30
FI47183B (enExample) 1973-07-02
FI47574C (fi) 1974-01-10
AT302544B (de) 1972-10-25
CS155250B2 (enExample) 1974-05-30
NL166696B (nl) 1981-04-15
JPS5028957B1 (enExample) 1975-09-19
IL35788A (en) 1973-05-31
US3712884A (en) 1973-01-23
BG18865A3 (bg) 1975-03-20
FR2081328B1 (enExample) 1974-08-23
ZA708221B (en) 1971-10-27
NL7017664A (enExample) 1971-06-08
SE356046B (enExample) 1973-05-14
NO131297C (enExample) 1975-05-07
ES386172A1 (es) 1973-03-16
NL166696C (nl) 1981-09-15
CH537378A (de) 1973-05-31
DK123354B (da) 1972-06-12
FI47574B (enExample) 1973-10-01
IL35788A0 (en) 1971-02-25
DK123714B (da) 1972-07-24
SU373935A3 (enExample) 1973-03-12
NO131297B (enExample) 1975-01-27
FI47183C (fi) 1973-10-10
RO58835A (enExample) 1975-11-15
PL81222B1 (enExample) 1975-08-30
YU34302B (en) 1979-04-30

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PE20 Patent expired after termination of 20 years