GB1267475A - Method for improving the stability of enzymes - Google Patents

Method for improving the stability of enzymes

Info

Publication number
GB1267475A
GB1267475A GB06770/70A GB1677070A GB1267475A GB 1267475 A GB1267475 A GB 1267475A GB 06770/70 A GB06770/70 A GB 06770/70A GB 1677070 A GB1677070 A GB 1677070A GB 1267475 A GB1267475 A GB 1267475A
Authority
GB
United Kingdom
Prior art keywords
enzyme
treating zone
enzymes
april
direct contact
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB06770/70A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gray Industries Inc
Original Assignee
Gray Industries Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gray Industries Inc filed Critical Gray Industries Inc
Publication of GB1267475A publication Critical patent/GB1267475A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/10—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
    • A61K41/13—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultrasonic waves

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

1,267,475. Stabilizing enzymes. GRAY INDUSTRIES Inc. 8 April, 1970 [17 April, 1969], No. 16770/70. Heading C3H. A method of improving the stability of an enzyme comprises cooling the enzyme in aqueous medium to below 50‹ F., and then, in quick succession, (a) subjecting the enzyme in a treating zone, while held in a closed, microwave-permeable container within said treating zone, to microwave energy through a moving atmosphere of coolant gas, for a period short of inactivation of the enzyme, said moving atmosphere being in direct contact with microwavepermeable walls of said container but outof direct contact with said enzyme and being at a temperature below 60‹ F. upon its admission to said treating zone; (b) discontinuing exposure of said enzyme to said microwave energy at the end of said period and (c) cooling said enzyme. The energy may be at 1000 to 5000 mc/s. The gas may be air, C0 2 , nitrogen, A, He, Ne, Kr, Xe, or ethyleneoxide. Examples releat to lactic dehydrogenase, serum glutamic oxolacetic transaminase, deoxyribonuclease, amylase, and blood serum (con taining many enzymes).
GB06770/70A 1969-04-17 1970-04-08 Method for improving the stability of enzymes Expired GB1267475A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81718169A 1969-04-17 1969-04-17

Publications (1)

Publication Number Publication Date
GB1267475A true GB1267475A (en) 1972-03-22

Family

ID=25222518

Family Applications (1)

Application Number Title Priority Date Filing Date
GB06770/70A Expired GB1267475A (en) 1969-04-17 1970-04-08 Method for improving the stability of enzymes

Country Status (14)

Country Link
US (1) US3645849A (en)
AT (1) AT295453B (en)
AU (1) AU1362570A (en)
BE (1) BE749082A (en)
CA (1) CA920524A (en)
CH (1) CH525914A (en)
DE (1) DE2017571C3 (en)
ES (1) ES378692A1 (en)
FR (1) FR2039250A1 (en)
GB (1) GB1267475A (en)
IL (1) IL34291A (en)
NL (1) NL7005554A (en)
SE (1) SE355817B (en)
TR (1) TR16728A (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL58541A (en) * 1978-11-01 1982-02-28 Nordisk Insulinlab Antihemophilic factor preparation from human blood plasma and a process for producing it
US4250139A (en) * 1979-02-01 1981-02-10 Collagen Corporation Microwave sterilization of dry protein
US4994237A (en) * 1987-10-02 1991-02-19 The Beth Israel Hospital Association Microwave preservation of bioprostheses
US5283034A (en) * 1989-06-29 1994-02-01 Applied Immune Sciences, Inc. Stabilization of sterilized surfaces for research and medical use
US6143508A (en) * 1989-06-29 2000-11-07 Rhone-Poulenc Rorer Pharmaceuticals Inc. Device and process for cell capture and recovery
CA1340565C (en) 1989-06-29 1999-05-25 Thomas B. Okarma Device and process for cell capture and recovery
US5372149A (en) * 1992-03-25 1994-12-13 Roth; David S. Sterilization process in the manufacturing of snuff
US5534026A (en) * 1992-04-02 1996-07-09 The Penn State Research Foundation Preparation of inexpensive, HIV-free human skin allograft
EP0956123B1 (en) * 1996-01-17 2005-12-28 Tauw B.V. Method for processing a sample
US5730933A (en) * 1996-04-16 1998-03-24 Depuy Orthopaedics, Inc. Radiation sterilization of biologically active compounds
NL1005028C2 (en) * 1997-01-17 1998-07-20 Franciscus Matheus Everaerts Controlling enzyme reactions in polar solvent
AU2007225040A1 (en) * 2006-03-15 2007-09-20 Promethean Lifesciences, Inc. Preparation and storage of stable, antimicrobially active materials

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2683682A (en) * 1950-02-06 1954-07-13 Research Corp Differential inactivation of enzymes
US3006815A (en) * 1956-08-24 1961-10-31 Fermco Lab Inc Heat stabilization of enzymes and method
US3284301A (en) * 1963-08-28 1966-11-08 American Cyanamid Co Plasmin sterilization
US3494723A (en) * 1967-12-05 1970-02-10 Gray Ind Inc Method and apparatus for controlling microorganisms and enzymes

Also Published As

Publication number Publication date
CH525914A (en) 1972-07-31
BE749082A (en) 1970-10-19
FR2039250A1 (en) 1971-01-15
DE2017571C3 (en) 1973-10-04
CA920524A (en) 1973-02-06
AT295453B (en) 1972-01-10
ES378692A1 (en) 1972-07-16
AU1362570A (en) 1971-10-14
SE355817B (en) 1973-05-07
TR16728A (en) 1973-03-01
IL34291A0 (en) 1970-06-17
IL34291A (en) 1973-03-30
US3645849A (en) 1972-02-29
DE2017571B2 (en) 1973-03-01
DE2017571A1 (en) 1970-10-29
NL7005554A (en) 1970-10-20

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