GB1238894A - - Google Patents

Info

Publication number
GB1238894A
GB1238894A GB1238894DA GB1238894A GB 1238894 A GB1238894 A GB 1238894A GB 1238894D A GB1238894D A GB 1238894DA GB 1238894 A GB1238894 A GB 1238894A
Authority
GB
United Kingdom
Prior art keywords
oct
prepared
acid esters
esterification
alkanoic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP42068693A external-priority patent/JPS502494B1/ja
Application filed filed Critical
Publication of GB1238894A publication Critical patent/GB1238894A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1,238,894. #-Guanidino alkanoic acid esters. S. FUJII. 23 Oct., 1968 [24 Oct., 1967 (2)], No. 50414/68. Heading C2C. #-Guanidino alkanoic acid esters of general formula H 2 NC(:NH)NH(CH 2 ) n COOR (in which R is a carboxylbenzyl group which may carry further groups and n is 3, 4 or 5) and their acid addition salts, may be prepared (a) by esterification of the corresponding free carboxylic acids with an alcohol ROH, or (b) by reacting a carboxybenzyl #-amino alkanoate (prepared by conventional esterification) with either S-methylthiourea or cyanamide. The compounds inhibit the hydrolysis of arginine ester by kallikrein and of casein by plasmin, and may be administered in conventional enteral or parenteral forms.
GB1238894D 1967-10-24 1968-10-23 Expired GB1238894A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP42068693A JPS502494B1 (en) 1967-10-24 1967-10-24
JP6869267 1967-10-24

Publications (1)

Publication Number Publication Date
GB1238894A true GB1238894A (en) 1971-07-14

Family

ID=26409892

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1238894D Expired GB1238894A (en) 1967-10-24 1968-10-23

Country Status (2)

Country Link
DE (1) DE1804999C3 (en)
GB (1) GB1238894A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1167678B (en) * 1960-12-09 1964-04-09 Motobecane Ateliers Power transmission for mopeds
BE757496A (en) * 1969-10-14 1971-03-16 Ono Pharmaceutical Co NEW PHENYL ESTERS OF GUANIDINOCAPROIC ACID AND THEIR PRODUCTION
AT397247B (en) * 1992-05-26 1994-02-25 Chemie Linz Gmbh GUANIDINOHYDROXYACETIC ACID, METHOD FOR THE PRODUCTION AND USE
TW300883B (en) * 1994-07-26 1997-03-21 Kao Corp

Also Published As

Publication number Publication date
DE1804999C3 (en) 1980-11-06
DE1804999B2 (en) 1976-09-09
DE1804999A1 (en) 1969-05-22

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee