GB1235953A - Novel pyridine derivatives, compositions containing the same, and methods of preparing the same - Google Patents
Novel pyridine derivatives, compositions containing the same, and methods of preparing the sameInfo
- Publication number
- GB1235953A GB1235953A GB4708869A GB4708869A GB1235953A GB 1235953 A GB1235953 A GB 1235953A GB 4708869 A GB4708869 A GB 4708869A GB 4708869 A GB4708869 A GB 4708869A GB 1235953 A GB1235953 A GB 1235953A
- Authority
- GB
- United Kingdom
- Prior art keywords
- chlorophenoxy
- same
- nicotinyl
- isobutyrate
- preparing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1,235,953. Nicotinyl α - (p - chlorophenoxy)- isobutyrate. ISTITUTO CHEMIOTERAPICO ITALIANO S.p.A. 24 Sept., 1969 [19 Feb., 1969], No. 47088/69. Heading C2C. Novel nicotinyl α - (p - chlorophenoxy) isobutyrate and pharmaceutically acceptable acid addition salts thereof are prepared by reaction of α-(p-chlorophenoxy) isobutyric acid with thionyl chloride and reaction of the resulting α - (p - chlorophenoxy) isobutyryl chloride with nicotinyl alcohol in the presence of pyridine, followed optionally by salification of the product. Pharmaceutical compositions having antihypercholesteremic and vasodilatory activity comprise, as active ingredient, nicotinyl α-(p-chlorophenoxy) isobutyrate or a pharmaceutically acceptable acid addition salt thereof, together with a non-toxic carrier therefor, and may be administered orally.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80075369A | 1969-02-19 | 1969-02-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1235953A true GB1235953A (en) | 1971-06-16 |
Family
ID=25179263
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB4708869A Expired GB1235953A (en) | 1969-02-19 | 1969-09-24 | Novel pyridine derivatives, compositions containing the same, and methods of preparing the same |
Country Status (9)
Country | Link |
---|---|
BE (1) | BE739770A (en) |
BR (1) | BR6913840D0 (en) |
CH (1) | CH503730A (en) |
DE (1) | DE1948320A1 (en) |
ES (1) | ES372134A1 (en) |
FR (1) | FR2031513B1 (en) |
GB (1) | GB1235953A (en) |
LU (1) | LU59635A1 (en) |
NL (1) | NL6916009A (en) |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH518937A (en) * | 1968-07-31 | 1972-02-15 | Siphar Sa | Process for the preparation of two new esters |
-
1969
- 1969-09-24 DE DE19691948320 patent/DE1948320A1/en active Pending
- 1969-09-24 GB GB4708869A patent/GB1235953A/en not_active Expired
- 1969-09-29 CH CH1461969A patent/CH503730A/en not_active IP Right Cessation
- 1969-10-01 FR FR6933525A patent/FR2031513B1/fr not_active Expired
- 1969-10-02 ES ES372134A patent/ES372134A1/en not_active Expired
- 1969-10-02 BE BE739770D patent/BE739770A/xx unknown
- 1969-10-14 LU LU59635D patent/LU59635A1/xx unknown
- 1969-10-23 NL NL6916009A patent/NL6916009A/xx unknown
- 1969-11-03 BR BR21384069A patent/BR6913840D0/en unknown
Also Published As
Publication number | Publication date |
---|---|
LU59635A1 (en) | 1970-01-12 |
FR2031513A1 (en) | 1970-11-20 |
BR6913840D0 (en) | 1973-02-13 |
BE739770A (en) | 1970-03-16 |
NL6916009A (en) | 1970-08-21 |
ES372134A1 (en) | 1971-09-16 |
CH503730A (en) | 1971-02-28 |
FR2031513B1 (en) | 1973-07-13 |
DE1948320A1 (en) | 1970-09-10 |
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