GB1184104A - The Preparation of 5alpha-Halo-6beta-Acyloxy Steroids and their Conversion to 5alpha-Halo-6beta-Hydroxy Steroids - Google Patents
The Preparation of 5alpha-Halo-6beta-Acyloxy Steroids and their Conversion to 5alpha-Halo-6beta-Hydroxy SteroidsInfo
- Publication number
- GB1184104A GB1184104A GB07023/67A GB1702367A GB1184104A GB 1184104 A GB1184104 A GB 1184104A GB 07023/67 A GB07023/67 A GB 07023/67A GB 1702367 A GB1702367 A GB 1702367A GB 1184104 A GB1184104 A GB 1184104A
- Authority
- GB
- United Kingdom
- Prior art keywords
- steroids
- halo
- 6beta
- 5alpha
- acyloxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000006243 chemical reaction Methods 0.000 title abstract 3
- CPELXLSAUQHCOX-UHFFFAOYSA-N Hydrogen bromide Chemical compound Br CPELXLSAUQHCOX-UHFFFAOYSA-N 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- 239000007858 starting material Substances 0.000 abstract 2
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001735 carboxylic acids Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000002118 epoxides Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- -1 hydrocarbon carboxylic acids Chemical class 0.000 abstract 1
- 229910000042 hydrogen bromide Inorganic materials 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- BWHLPLXXIDYSNW-UHFFFAOYSA-N ketorolac tromethamine Chemical compound OCC(N)(CO)CO.OC(=O)C1CCN2C1=CC=C2C(=O)C1=CC=CC=C1 BWHLPLXXIDYSNW-UHFFFAOYSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000011701 zinc Substances 0.000 abstract 1
- 229910052725 zinc Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54467866A | 1966-04-25 | 1966-04-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1184104A true GB1184104A (en) | 1970-03-11 |
Family
ID=24173132
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB07023/67A Expired GB1184104A (en) | 1966-04-25 | 1967-04-13 | The Preparation of 5alpha-Halo-6beta-Acyloxy Steroids and their Conversion to 5alpha-Halo-6beta-Hydroxy Steroids |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US3452003A (enExample) |
| JP (2) | JPS5611719B1 (enExample) |
| CH (1) | CH513836A (enExample) |
| DE (1) | DE1618875C3 (enExample) |
| GB (1) | GB1184104A (enExample) |
| NL (2) | NL6705686A (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61104428U (enExample) * | 1984-12-12 | 1986-07-03 | ||
| AU2019351004B2 (en) * | 2018-09-28 | 2023-09-14 | The Regents Of The University Of Michigan | Halogenated cholesterol analogues and methods of making and using same |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3138589A (en) * | 1959-03-04 | 1964-06-23 | Syntex Corp | Process for the production of 6-halo-3-keto-delta4, 6-steroids |
| US3278528A (en) * | 1962-12-20 | 1966-10-11 | Syntex Corp | 5alpha-halo-4beta, 19-oxido steroids and process for production thereof |
| US3235545A (en) * | 1964-05-25 | 1966-02-15 | Olin Mathieson | 6beta, 19-oxido-16, 17-acetals and ketals of the pregnane series and intermediates therefor |
-
1966
- 1966-04-25 US US544678A patent/US3452003A/en not_active Expired - Lifetime
-
1967
- 1967-04-13 GB GB07023/67A patent/GB1184104A/en not_active Expired
- 1967-04-14 DE DE1618875A patent/DE1618875C3/de not_active Expired
- 1967-04-20 CH CH564767A patent/CH513836A/de not_active IP Right Cessation
- 1967-04-21 NL NL6705686A patent/NL6705686A/xx unknown
- 1967-04-25 JP JP2609667A patent/JPS5611719B1/ja active Pending
-
1972
- 1972-01-06 NL NL7200176A patent/NL7200176A/xx unknown
-
1979
- 1979-02-27 JP JP2246879A patent/JPS5526156B1/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE1793775B2 (de) | 1975-11-06 |
| DE1618875C3 (de) | 1974-06-20 |
| NL6705686A (enExample) | 1967-10-26 |
| US3452003A (en) | 1969-06-24 |
| DE1618875A1 (enExample) | 1972-06-08 |
| JPS5611719B1 (enExample) | 1981-03-16 |
| DE1793775A1 (de) | 1974-07-04 |
| NL7200176A (enExample) | 1972-04-25 |
| JPS5526156B1 (enExample) | 1980-07-11 |
| CH513836A (de) | 1971-10-15 |
| DE1618875B2 (de) | 1973-11-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |