GB1145324A - Novel unsaturated steroidal lactone - Google Patents
Novel unsaturated steroidal lactoneInfo
- Publication number
- GB1145324A GB1145324A GB3961968A GB3961968A GB1145324A GB 1145324 A GB1145324 A GB 1145324A GB 3961968 A GB3961968 A GB 3961968A GB 3961968 A GB3961968 A GB 3961968A GB 1145324 A GB1145324 A GB 1145324A
- Authority
- GB
- United Kingdom
- Prior art keywords
- oxa
- hydroxy
- converted
- novel unsaturated
- selective reduction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
- C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
- C07J73/003—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by oxygen as hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Abstract
1,145,324. A 2-oxa-steroid. G. D. SEARLE & CO. 12 April, 1966, No. 39619/68. Divided out of 1,145,322. Heading C2C. The novel 17#-hydroxy-2-oxa-estr-5(10)-en-3- one is prepared by selective reduction of the corresponding 17-keto compound which is first converted into the corresponding alkali metal or alkaline earth metal salt and in this form has the formula (wherein M is the metal) by treatment with alkali. The selective reduction may be effected with an alkali metal aluminium hydride or borohydride. The product may be converted to 17# - hydroxy - 2 - oxa - estra - 4,9(10) - dien - 3 - one by reaction with bromine in the presence of an organic base.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB3961968A GB1145324A (en) | 1966-04-12 | 1966-04-12 | Novel unsaturated steroidal lactone |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB3961968A GB1145324A (en) | 1966-04-12 | 1966-04-12 | Novel unsaturated steroidal lactone |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1145324A true GB1145324A (en) | 1969-03-12 |
Family
ID=10410553
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB3961968A Expired GB1145324A (en) | 1966-04-12 | 1966-04-12 | Novel unsaturated steroidal lactone |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB1145324A (en) |
-
1966
- 1966-04-12 GB GB3961968A patent/GB1145324A/en not_active Expired
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