GB1183968A - A Process for the Production of Substituted Phenyl Acetic Acids - Google Patents
A Process for the Production of Substituted Phenyl Acetic AcidsInfo
- Publication number
- GB1183968A GB1183968A GB4572467A GB4572467A GB1183968A GB 1183968 A GB1183968 A GB 1183968A GB 4572467 A GB4572467 A GB 4572467A GB 4572467 A GB4572467 A GB 4572467A GB 1183968 A GB1183968 A GB 1183968A
- Authority
- GB
- United Kingdom
- Prior art keywords
- anilino
- general formula
- hydrogen
- alkyl
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
1,183,968. o-Anilino-phenylacetic acid derivatives. J. R. GEIGY A.G. 6 Oct., 1967 [7 Oct., 1966], No. 45724/67. Heading C2C. o-Anilino-phenylacetic acid derivatives of the general formula wherein R 1 and R 2 are each a C 1-4 alkyl or C 1-4 alkoxy group or a fluorine, chlorine or bromine atom; R 3 is hydrogen or is defined as R 1 and R 2 ; R 4 is hydrogen, a C 1-4 alkyl or C 1-4 alkoxy group, a fluorine, chlorine or bromine atom or the trifluoromethyl group; and R 5 is hydrogen or a C 1-4 alkyl group, are prepared by heating an o-anilino-acetophenone of the general formula with sulphur and morpholine according to the Willgerodt-Kindler method and hydrolysing the resulting 4 - [(o - anilinophenyl) - thioacetyl]- morpholine of the general formula o-Anilino-acetophenones of the second general formula above are prepared by reacting (ethoxymagnesium)-malonic acid diethyl ester with an appropriately substituted N-phenyl-anthranilic acid chloride in absolute ethanol and heating the resulting substituted (N-phenyl-anthraniloyl)-malonic acid diethyl ester in an acidic medium.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1451766A CH470349A (en) | 1966-10-07 | 1966-10-07 | Process for the production of new substituted phenylacetic acids |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1183968A true GB1183968A (en) | 1970-03-11 |
Family
ID=4401487
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB4572467A Expired GB1183968A (en) | 1966-10-07 | 1967-10-06 | A Process for the Production of Substituted Phenyl Acetic Acids |
Country Status (12)
Country | Link |
---|---|
AT (1) | AT273935B (en) |
BE (1) | BE704820A (en) |
CH (1) | CH470349A (en) |
DK (1) | DK120243B (en) |
ES (1) | ES345831A1 (en) |
FI (1) | FI47880C (en) |
GB (1) | GB1183968A (en) |
GR (1) | GR37760B (en) |
NL (1) | NL6713629A (en) |
NO (1) | NO121047B (en) |
SE (1) | SE345997B (en) |
YU (1) | YU32369B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
LU83138A1 (en) * | 1981-02-16 | 1981-09-11 | T Eckert | TOPICAL PHARMACEUTICAL PREPARATIONS, CONTAINING SALTS OF ALKANCARBONIC ACIDS AND NEW CARBONIC ACID SALTS AND METHOD FOR THE PRODUCTION THEREOF |
AT370721B (en) * | 1981-02-24 | 1983-04-25 | Ciba Geigy Ag | METHOD FOR PRODUCING NEW SALTS OF 2- (2,6-DICHLORANILINO) -PHENYLACETIC ACID, THE |
-
1966
- 1966-10-07 CH CH1451766A patent/CH470349A/en not_active IP Right Cessation
-
1967
- 1967-10-04 FI FI265567A patent/FI47880C/en active
- 1967-10-06 GB GB4572467A patent/GB1183968A/en not_active Expired
- 1967-10-06 NO NO17002467A patent/NO121047B/no unknown
- 1967-10-06 ES ES345831A patent/ES345831A1/en not_active Expired
- 1967-10-06 DK DK497867A patent/DK120243B/en not_active IP Right Cessation
- 1967-10-06 GR GR670137760A patent/GR37760B/en unknown
- 1967-10-06 NL NL6713629A patent/NL6713629A/xx unknown
- 1967-10-06 BE BE704820D patent/BE704820A/xx unknown
- 1967-10-06 SE SE1371067A patent/SE345997B/xx unknown
- 1967-10-06 AT AT910467A patent/AT273935B/en active
- 1967-10-06 YU YU194267A patent/YU32369B/en unknown
Also Published As
Publication number | Publication date |
---|---|
ES345831A1 (en) | 1968-11-16 |
BE704820A (en) | 1968-04-08 |
FI47880B (en) | 1974-01-02 |
NO121047B (en) | 1971-01-11 |
AT273935B (en) | 1969-08-25 |
CH470349A (en) | 1969-03-31 |
SE345997B (en) | 1972-06-19 |
NL6713629A (en) | 1968-04-08 |
YU32369B (en) | 1974-10-31 |
DK120243B (en) | 1971-05-03 |
YU194267A (en) | 1974-04-30 |
GR37760B (en) | 1969-07-12 |
FI47880C (en) | 1974-04-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PLNP | Patent lapsed through nonpayment of renewal fees |