GB1174493A - New Benzimidazoles and process for their preparation - Google Patents
New Benzimidazoles and process for their preparationInfo
- Publication number
- GB1174493A GB1174493A GB3293367A GB3293367A GB1174493A GB 1174493 A GB1174493 A GB 1174493A GB 3293367 A GB3293367 A GB 3293367A GB 3293367 A GB3293367 A GB 3293367A GB 1174493 A GB1174493 A GB 1174493A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- alkoxy
- benzimidazoles
- halogen
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001556 benzimidazoles Chemical class 0.000 title abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- LQNUZADURLCDLV-UHFFFAOYSA-N nitrobenzene Chemical compound [O-][N+](=O)C1=CC=CC=C1 LQNUZADURLCDLV-UHFFFAOYSA-N 0.000 abstract 2
- WDCYWAQPCXBPJA-UHFFFAOYSA-N 1,3-dinitrobenzene Chemical compound [O-][N+](=O)C1=CC=CC([N+]([O-])=O)=C1 WDCYWAQPCXBPJA-UHFFFAOYSA-N 0.000 abstract 1
- NFCPRRWCTNLGSN-UHFFFAOYSA-N 2-n-phenylbenzene-1,2-diamine Chemical class NC1=CC=CC=C1NC1=CC=CC=C1 NFCPRRWCTNLGSN-UHFFFAOYSA-N 0.000 abstract 1
- 125000002431 aminoalkoxy group Chemical group 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 150000003935 benzaldehydes Chemical class 0.000 abstract 1
- HUMNYLRZRPPJDN-UHFFFAOYSA-N benzenecarboxaldehyde Natural products O=CC1=CC=CC=C1 HUMNYLRZRPPJDN-UHFFFAOYSA-N 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- QNGNSVIICDLXHT-UHFFFAOYSA-N para-ethylbenzaldehyde Natural products CCC1=CC=C(C=O)C=C1 QNGNSVIICDLXHT-UHFFFAOYSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3293367A GB1174493A (en) | 1967-05-10 | 1967-05-10 | New Benzimidazoles and process for their preparation |
| BE714652D BE714652A (cs) | 1967-05-10 | 1968-05-03 | |
| CH668268A CH497433A (fr) | 1967-05-10 | 1968-05-06 | Procédé de préparation de nouveaux dérivés des benzimidazoles |
| FR1561049D FR1561049A (cs) | 1967-05-10 | 1968-05-07 | |
| NL6806574A NL6806574A (cs) | 1967-05-10 | 1968-05-09 | |
| DE19681770362 DE1770362A1 (de) | 1967-05-10 | 1968-05-09 | Benzimidazole und Verfahren zu ihrer Herstellung |
| FR151710A FR7408M (cs) | 1967-05-10 | 1968-05-14 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2180467 | 1967-05-10 | ||
| GB3293367A GB1174493A (en) | 1967-05-10 | 1967-05-10 | New Benzimidazoles and process for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1174493A true GB1174493A (en) | 1969-12-17 |
Family
ID=26255530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3293367A Expired GB1174493A (en) | 1967-05-10 | 1967-05-10 | New Benzimidazoles and process for their preparation |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE714652A (cs) |
| CH (1) | CH497433A (cs) |
| DE (1) | DE1770362A1 (cs) |
| FR (2) | FR1561049A (cs) |
| GB (1) | GB1174493A (cs) |
| NL (1) | NL6806574A (cs) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995007263A1 (de) * | 1993-09-09 | 1995-03-16 | Schering Aktiengesellschaft | 1,2-di(het)aryl-benzimidazol derivate, deren herstellung und deren verwendung als prostazyklin-(pgi2)-mimetika |
| WO1995030659A1 (en) * | 1994-05-10 | 1995-11-16 | Warner-Lambert Company | Benzimidazole and imidazopyridine derivatives, their preparation and their use as dopaminergic agents, esp. selective for the dopamine d3 receptor |
| EP0694535A1 (en) * | 1994-04-29 | 1996-01-31 | Eli Lilly And Company | Non-peptidyl tachykinin receptor antagonists |
| WO2004000817A3 (en) * | 2002-06-24 | 2004-05-21 | Pfizer Prod Inc | Benzimidazole compounds and their use as estrogen agonists/antagonists |
| US7115645B2 (en) | 2000-01-14 | 2006-10-03 | Schering Aktiengesellschaft | 1,2 diarylbenzimidazoles and their pharmaceutical use |
| US7329679B2 (en) | 2000-01-27 | 2008-02-12 | Schering Aktiengesellschaft | 1,2 Diarylbenzimidazoles and their pharmaceutical use |
| JP2008303211A (ja) * | 2003-03-13 | 2008-12-18 | Idemitsu Kosan Co Ltd | 新規含窒素複素環誘導体及びそれを用いた有機エレクトロルミネッセンス素子 |
-
1967
- 1967-05-10 GB GB3293367A patent/GB1174493A/en not_active Expired
-
1968
- 1968-05-03 BE BE714652D patent/BE714652A/xx unknown
- 1968-05-06 CH CH668268A patent/CH497433A/fr not_active IP Right Cessation
- 1968-05-07 FR FR1561049D patent/FR1561049A/fr not_active Expired
- 1968-05-09 NL NL6806574A patent/NL6806574A/xx unknown
- 1968-05-09 DE DE19681770362 patent/DE1770362A1/de active Pending
- 1968-05-14 FR FR151710A patent/FR7408M/fr not_active Expired
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995007263A1 (de) * | 1993-09-09 | 1995-03-16 | Schering Aktiengesellschaft | 1,2-di(het)aryl-benzimidazol derivate, deren herstellung und deren verwendung als prostazyklin-(pgi2)-mimetika |
| EP0694535A1 (en) * | 1994-04-29 | 1996-01-31 | Eli Lilly And Company | Non-peptidyl tachykinin receptor antagonists |
| WO1995030659A1 (en) * | 1994-05-10 | 1995-11-16 | Warner-Lambert Company | Benzimidazole and imidazopyridine derivatives, their preparation and their use as dopaminergic agents, esp. selective for the dopamine d3 receptor |
| US7115645B2 (en) | 2000-01-14 | 2006-10-03 | Schering Aktiengesellschaft | 1,2 diarylbenzimidazoles and their pharmaceutical use |
| US7329679B2 (en) | 2000-01-27 | 2008-02-12 | Schering Aktiengesellschaft | 1,2 Diarylbenzimidazoles and their pharmaceutical use |
| US7345075B2 (en) | 2000-01-27 | 2008-03-18 | Schering Aktiengesellschaft | 1,2 diarylbenzimidazoles and their pharmaceutical use |
| WO2004000817A3 (en) * | 2002-06-24 | 2004-05-21 | Pfizer Prod Inc | Benzimidazole compounds and their use as estrogen agonists/antagonists |
| JP2008303211A (ja) * | 2003-03-13 | 2008-12-18 | Idemitsu Kosan Co Ltd | 新規含窒素複素環誘導体及びそれを用いた有機エレクトロルミネッセンス素子 |
Also Published As
| Publication number | Publication date |
|---|---|
| FR7408M (cs) | 1969-11-03 |
| CH497433A (fr) | 1970-10-15 |
| DE1770362A1 (de) | 1971-10-21 |
| BE714652A (cs) | 1968-09-30 |
| NL6806574A (cs) | 1968-11-11 |
| FR1561049A (cs) | 1969-03-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| 435 | Patent endorsed 'licences of right' on the date specified (sect. 35/1949) | ||
| PCNP | Patent ceased through non-payment of renewal fee |