GB1165099A - 2-Aryl-2-Imidazolines - Google Patents
2-Aryl-2-ImidazolinesInfo
- Publication number
- GB1165099A GB1165099A GB05809/68A GB1580968A GB1165099A GB 1165099 A GB1165099 A GB 1165099A GB 05809/68 A GB05809/68 A GB 05809/68A GB 1580968 A GB1580968 A GB 1580968A GB 1165099 A GB1165099 A GB 1165099A
- Authority
- GB
- United Kingdom
- Prior art keywords
- trichlorobenzyl
- positions
- trichlorophenylacetonitrile
- reaction
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000006243 chemical reaction Methods 0.000 abstract 4
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- CYPFPSICESWOSR-UHFFFAOYSA-N 2-(2,4,5-trichlorophenyl)acetonitrile Chemical compound ClC1=CC(Cl)=C(CC#N)C=C1Cl CYPFPSICESWOSR-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- HOLOJLLLDKVVJY-UHFFFAOYSA-N 1,2,4-trichloro-3-(chloromethyl)benzene Chemical compound ClCC1=C(Cl)C=CC(Cl)=C1Cl HOLOJLLLDKVVJY-UHFFFAOYSA-N 0.000 abstract 1
- ZUZLGSONCFESPE-UHFFFAOYSA-N 2-(2,3,6-trichlorophenyl)acetonitrile Chemical compound ClC1=CC=C(Cl)C(CC#N)=C1Cl ZUZLGSONCFESPE-UHFFFAOYSA-N 0.000 abstract 1
- RZAARLYULZKCEK-UHFFFAOYSA-N 2-[(2,3,6-trichlorophenyl)methyl]-4,5-dihydro-1H-imidazole Chemical compound ClC1=C(CC=2NCCN2)C(=CC=C1Cl)Cl RZAARLYULZKCEK-UHFFFAOYSA-N 0.000 abstract 1
- HVCCFMAPGCBCHZ-UHFFFAOYSA-N 2-aminoethylazanium;4-methylbenzenesulfonate Chemical compound NCCN.CC1=CC=C(S(O)(=O)=O)C=C1 HVCCFMAPGCBCHZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- KXZJHVJKXJLBKO-UHFFFAOYSA-N chembl1408157 Chemical compound N=1C2=CC=CC=C2C(C(=O)O)=CC=1C1=CC=C(O)C=C1 KXZJHVJKXJLBKO-UHFFFAOYSA-N 0.000 abstract 1
- VAYGXNSJCAHWJZ-UHFFFAOYSA-N dimethyl sulfate Chemical compound COS(=O)(=O)OC VAYGXNSJCAHWJZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000005490 tosylate group Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62829867A | 1967-04-04 | 1967-04-04 | |
| US62830567A | 1967-04-04 | 1967-04-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1165099A true GB1165099A (en) | 1969-09-24 |
Family
ID=27090673
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB05809/68A Expired GB1165099A (en) | 1967-04-04 | 1968-04-02 | 2-Aryl-2-Imidazolines |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US3423422A (enExample) |
| BE (1) | BE713193A (enExample) |
| CH (1) | CH515908A (enExample) |
| DE (1) | DE1770114A1 (enExample) |
| DK (1) | DK115776B (enExample) |
| FR (2) | FR1580194A (enExample) |
| GB (1) | GB1165099A (enExample) |
| NL (1) | NL6804671A (enExample) |
| NO (1) | NO121664B (enExample) |
| SE (1) | SE342452B (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1417174A (en) * | 1972-11-30 | 1975-12-10 | Hexachimie | 1-2-delta2-imidazolinyl-2,2-diarylcoclopropanes |
| EP4204404A4 (en) * | 2020-08-27 | 2024-12-25 | Curasen Therapeutics, Inc. | Alpha1a-adrenergic receptor agonists and methods of use |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2919274A (en) * | 1957-09-17 | 1959-12-29 | Sahyun Melville | Amidines |
-
1967
- 1967-04-04 US US628298A patent/US3423422A/en not_active Expired - Lifetime
- 1967-04-04 US US628305A patent/US3423423A/en not_active Expired - Lifetime
-
1968
- 1968-03-22 NO NO1118/68A patent/NO121664B/no unknown
- 1968-03-29 FR FR1580194D patent/FR1580194A/fr not_active Expired
- 1968-04-01 SE SE4281/68A patent/SE342452B/xx unknown
- 1968-04-02 GB GB05809/68A patent/GB1165099A/en not_active Expired
- 1968-04-02 DE DE19681770114 patent/DE1770114A1/de active Pending
- 1968-04-03 DK DK147368AA patent/DK115776B/da unknown
- 1968-04-03 NL NL6804671A patent/NL6804671A/xx unknown
- 1968-04-03 BE BE713193D patent/BE713193A/xx unknown
- 1968-04-04 CH CH509468A patent/CH515908A/de not_active IP Right Cessation
- 1968-06-28 FR FR157206A patent/FR8077M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US3423422A (en) | 1969-01-21 |
| NO121664B (enExample) | 1971-03-29 |
| FR1580194A (enExample) | 1969-09-05 |
| BE713193A (enExample) | 1968-10-03 |
| NL6804671A (enExample) | 1968-10-07 |
| CH515908A (de) | 1971-11-30 |
| US3423423A (en) | 1969-01-21 |
| FR8077M (enExample) | 1970-07-15 |
| SE342452B (enExample) | 1972-02-07 |
| DK115776B (da) | 1969-11-10 |
| DE1770114A1 (de) | 1971-09-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |