GB1145644A - Novel pregnane derivatives - Google Patents
Novel pregnane derivativesInfo
- Publication number
- GB1145644A GB1145644A GB40673/68A GB4067368A GB1145644A GB 1145644 A GB1145644 A GB 1145644A GB 40673/68 A GB40673/68 A GB 40673/68A GB 4067368 A GB4067368 A GB 4067368A GB 1145644 A GB1145644 A GB 1145644A
- Authority
- GB
- United Kingdom
- Prior art keywords
- carboxylic acid
- pregnane
- methyl ester
- acid methyl
- isopropylidenedioxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1,145,644. Pregnane derivatives. F. HOFFMANNLA ROCHE & CO. A.G. 12 Aug., 1966 [13 Aug., 1965; 8 Oct., 1965], No. 40673/68. Divided out of 1,145,641. Heading C2U. The novel compound 2#,3#-isopropylidenedioxy - 5,6# - oxido - pregnane 20 - carboxylic acid methyl ester prepared by heating 2#,3#- isopropylidenedioxy - 5α - acetoxy - 6# - hydroxy-pregnane 20-carboxylic acid methyl ester with potassium hydroxide and then treating the resulting carboxylic acid with diazomethane. The 5,6α-isomer of the above compound prepared by reacting 2#,3#-isopropylidenedioxy- 5α,6# - dihydroxy - pregnane 20 - carboxylic acid methyl ester with methanesulphonyl chloride and treating the resulting 6-mesyloxy derivative with sodium hydrogen carbonate in the presence of pyridine. 2#,3# - Dihydroxy - 5,6# - oxido - pregnane 20- carboxylic acid methyl ester prepared by heating 2#,3#,5α,6# - tetraacetoxy - pregnane - 20 - carboxylic acid methyl ester with potassium hydroxide and treating the resulting carboxylic acid with diazo-methane.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1143065A CH467760A (en) | 1965-08-13 | 1965-08-13 | Process for the preparation of 5B-H-6-keto steroids |
| CH1390765 | 1965-10-08 | ||
| CH123166 | 1966-01-28 | ||
| CH433666 | 1966-03-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1145644A true GB1145644A (en) | 1969-03-19 |
Family
ID=27428125
Family Applications (10)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB40679/68A Expired GB1145650A (en) | 1965-08-13 | 1966-08-12 | A novel pregnane derivative |
| GB40678/68A Expired GB1145649A (en) | 1965-08-13 | 1966-08-12 | Novel pregnane derivatives |
| GB36214/66A Expired GB1145641A (en) | 1965-08-13 | 1966-08-12 | A process for the manufacture of 5-ß-h-6-keto-steroids |
| GB40674/68A Expired GB1145645A (en) | 1965-08-13 | 1966-08-12 | Novel pregnane derivatives |
| GB40677/68A Expired GB1145648A (en) | 1965-08-13 | 1966-08-12 | Novel pregnane derivatives |
| GB40680/68A Expired GB1145651A (en) | 1965-08-13 | 1966-08-12 | A novel pregnane derivative |
| GB40672/68A Expired GB1145643A (en) | 1965-08-13 | 1966-08-12 | Novel 5-‡-h-6-keto-steroids |
| GB40676/68A Expired GB1145647A (en) | 1965-08-13 | 1966-08-12 | Novel 5-‡-h-6-keto-steroids |
| GB40673/68A Expired GB1145644A (en) | 1965-08-13 | 1966-08-12 | Novel pregnane derivatives |
| GB40675/68A Expired GB1145646A (en) | 1965-08-13 | 1966-08-12 | Novel pregnane derivatives |
Family Applications Before (8)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB40679/68A Expired GB1145650A (en) | 1965-08-13 | 1966-08-12 | A novel pregnane derivative |
| GB40678/68A Expired GB1145649A (en) | 1965-08-13 | 1966-08-12 | Novel pregnane derivatives |
| GB36214/66A Expired GB1145641A (en) | 1965-08-13 | 1966-08-12 | A process for the manufacture of 5-ß-h-6-keto-steroids |
| GB40674/68A Expired GB1145645A (en) | 1965-08-13 | 1966-08-12 | Novel pregnane derivatives |
| GB40677/68A Expired GB1145648A (en) | 1965-08-13 | 1966-08-12 | Novel pregnane derivatives |
| GB40680/68A Expired GB1145651A (en) | 1965-08-13 | 1966-08-12 | A novel pregnane derivative |
| GB40672/68A Expired GB1145643A (en) | 1965-08-13 | 1966-08-12 | Novel 5-‡-h-6-keto-steroids |
| GB40676/68A Expired GB1145647A (en) | 1965-08-13 | 1966-08-12 | Novel 5-‡-h-6-keto-steroids |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB40675/68A Expired GB1145646A (en) | 1965-08-13 | 1966-08-12 | Novel pregnane derivatives |
Country Status (11)
| Country | Link |
|---|---|
| AT (1) | AT268555B (en) |
| BE (1) | BE685305A (en) |
| BR (1) | BR6681938D0 (en) |
| CH (1) | CH467760A (en) |
| DK (2) | DK122664B (en) |
| ES (1) | ES330192A1 (en) |
| FI (1) | FI43596B (en) |
| GB (10) | GB1145650A (en) |
| IL (1) | IL26262A (en) |
| NL (1) | NL6611383A (en) |
| SE (2) | SE342813B (en) |
-
1965
- 1965-08-13 CH CH1143065A patent/CH467760A/en unknown
-
1966
- 1966-07-29 SE SE10329/66A patent/SE342813B/xx unknown
- 1966-07-29 SE SE7200223*3A patent/SE375536B/xx unknown
- 1966-07-29 AT AT729566A patent/AT268555B/en active
- 1966-08-03 IL IL26262A patent/IL26262A/en unknown
- 1966-08-08 BR BR181938/66A patent/BR6681938D0/en unknown
- 1966-08-10 BE BE685305D patent/BE685305A/xx unknown
- 1966-08-12 GB GB40679/68A patent/GB1145650A/en not_active Expired
- 1966-08-12 FI FI2120/66A patent/FI43596B/fi active
- 1966-08-12 GB GB40678/68A patent/GB1145649A/en not_active Expired
- 1966-08-12 DK DK414166AA patent/DK122664B/en unknown
- 1966-08-12 GB GB36214/66A patent/GB1145641A/en not_active Expired
- 1966-08-12 GB GB40674/68A patent/GB1145645A/en not_active Expired
- 1966-08-12 GB GB40677/68A patent/GB1145648A/en not_active Expired
- 1966-08-12 GB GB40680/68A patent/GB1145651A/en not_active Expired
- 1966-08-12 GB GB40672/68A patent/GB1145643A/en not_active Expired
- 1966-08-12 ES ES0330192A patent/ES330192A1/en not_active Expired
- 1966-08-12 NL NL6611383A patent/NL6611383A/xx unknown
- 1966-08-12 GB GB40676/68A patent/GB1145647A/en not_active Expired
- 1966-08-12 GB GB40673/68A patent/GB1145644A/en not_active Expired
- 1966-08-12 GB GB40675/68A patent/GB1145646A/en not_active Expired
-
1970
- 1970-08-31 DK DK446770AA patent/DK124479B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB1145646A (en) | 1969-03-19 |
| GB1145647A (en) | 1969-03-19 |
| AT268555B (en) | 1969-02-10 |
| GB1145648A (en) | 1969-03-19 |
| DK122664B (en) | 1972-03-27 |
| SE342813B (en) | 1972-02-21 |
| CH467760A (en) | 1969-01-31 |
| SE375536B (en) | 1975-04-21 |
| GB1145641A (en) | 1969-03-19 |
| GB1145649A (en) | 1969-03-19 |
| FI43596B (en) | 1971-02-01 |
| BR6681938D0 (en) | 1973-12-26 |
| BE685305A (en) | 1967-02-10 |
| IL26262A (en) | 1971-05-26 |
| GB1145651A (en) | 1969-03-19 |
| GB1145645A (en) | 1969-03-19 |
| DK124479B (en) | 1972-10-23 |
| ES330192A1 (en) | 1967-09-01 |
| NL6611383A (en) | 1967-02-14 |
| GB1145650A (en) | 1969-03-19 |
| GB1145643A (en) | 1969-03-19 |
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