GB1182441A - Production of Indole Derivatives - Google Patents

Production of Indole Derivatives

Info

Publication number
GB1182441A
GB1182441A GB5048366A GB5048366A GB1182441A GB 1182441 A GB1182441 A GB 1182441A GB 5048366 A GB5048366 A GB 5048366A GB 5048366 A GB5048366 A GB 5048366A GB 1182441 A GB1182441 A GB 1182441A
Authority
GB
United Kingdom
Prior art keywords
esters
hydrogen
indole derivatives
carbon atoms
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5048366A
Inventor
Svend Age Christensen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Priority to GB5048366A priority Critical patent/GB1182441A/en
Priority to DK553667A priority patent/DK121298B/en
Priority to NL6715201A priority patent/NL6715201A/xx
Priority to DE19671670002 priority patent/DE1670002A1/en
Priority to AT1011567A priority patent/AT281011B/en
Priority to SE1541767A priority patent/SE329161B/xx
Publication of GB1182441A publication Critical patent/GB1182441A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1,182,441. Indole acetic acids. MERCK & CO. Inc. 24 Jan., 1968 [10 Nov., 1966], No. 50483/66. Heading C2C. Indole derivatives of formula in which R<SP>1</SP> represent a hydrogen or halogen atom, an alkoxy group of not more than 4 carbon atoms, or a nitro group, R<SP>2</SP> represents a hydrogen atom or an alkyl group of 1-4 carbon atoms, and R<SP>3</SP> represents a hydrogen or halogen atom or a nitro group, are prepared by subjecting the corresponding triphenylmethyl esters, diphenylmethyl esters, 4,4<SP>1</SP>,4<SP>11</SP>-trimethoxy - triphenylmethyl esters, or 4,4<SP>1 </SP>- dimethoxy - diphenylmethyl esters to hydrolysis, or alcoholysis using an aqueous alcohol to produce the desired product.
GB5048366A 1966-11-10 1966-11-10 Production of Indole Derivatives Expired GB1182441A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
GB5048366A GB1182441A (en) 1966-11-10 1966-11-10 Production of Indole Derivatives
DK553667A DK121298B (en) 1966-11-10 1967-11-07 Process for the preparation of indole derivatives.
NL6715201A NL6715201A (en) 1966-11-10 1967-11-09
DE19671670002 DE1670002A1 (en) 1966-11-10 1967-11-09 Process for the production of indole derivatives
AT1011567A AT281011B (en) 1966-11-10 1967-11-10 Process for the production of indole derivatives
SE1541767A SE329161B (en) 1966-11-10 1967-11-10

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5048366A GB1182441A (en) 1966-11-10 1966-11-10 Production of Indole Derivatives

Publications (1)

Publication Number Publication Date
GB1182441A true GB1182441A (en) 1970-02-25

Family

ID=10456056

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5048366A Expired GB1182441A (en) 1966-11-10 1966-11-10 Production of Indole Derivatives

Country Status (6)

Country Link
AT (1) AT281011B (en)
DE (1) DE1670002A1 (en)
DK (1) DK121298B (en)
GB (1) GB1182441A (en)
NL (1) NL6715201A (en)
SE (1) SE329161B (en)

Also Published As

Publication number Publication date
DK121298B (en) 1971-10-04
SE329161B (en) 1970-10-05
DE1670002A1 (en) 1971-01-21
AT281011B (en) 1970-05-11
NL6715201A (en) 1968-05-13

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee