GB1130867A - The preparation of optically active -‡-methyl--‡-amino--ß-(hydroxyphenyl)propionic acids - Google Patents

The preparation of optically active -‡-methyl--‡-amino--ß-(hydroxyphenyl)propionic acids

Info

Publication number
GB1130867A
GB1130867A GB4680866A GB4680866A GB1130867A GB 1130867 A GB1130867 A GB 1130867A GB 4680866 A GB4680866 A GB 4680866A GB 4680866 A GB4680866 A GB 4680866A GB 1130867 A GB1130867 A GB 1130867A
Authority
GB
United Kingdom
Prior art keywords
hydroxyphenyl
amino
methyl
propionic acids
optically active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4680866A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB1130867A publication Critical patent/GB1130867A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00Compounds containing azido groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles

Abstract

1,130,867. α - Methyl - α - amino - # - (hydroxyphenyl)-propionic acids. MERCK & CO. Inc. 19 Oct., 1966 [22 Oct., 1965], No. 46808/66. Heading C2C. α - Methyl - α - amino - # - (hydroxyphenyl). propionic acids, e.g. L-methyltyrosine, are prepared by converting an optically active azide of formula wherein R is H or C 1-5 alkyl and R<SP>1</SP> is C 1-5 alkyl, into the corresponding isocyanate which is then hydrolysed. The azide starting materials may be prepared as in Specification 1,130,869.
GB4680866A 1965-10-22 1966-10-19 The preparation of optically active -‡-methyl--‡-amino--ß-(hydroxyphenyl)propionic acids Expired GB1130867A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50228565A 1965-10-22 1965-10-22

Publications (1)

Publication Number Publication Date
GB1130867A true GB1130867A (en) 1968-10-16

Family

ID=23997143

Family Applications (3)

Application Number Title Priority Date Filing Date
GB692068A Expired GB1130868A (en) 1965-10-22 1966-10-19 Alpha cyanoesters and their conversion to dicarboxylic derivatives
GB692168A Expired GB1130869A (en) 1965-10-22 1966-10-19 -‡-methyl--‡-carboalkoxy--ß-phenyl-propionic acid derivatives
GB4680866A Expired GB1130867A (en) 1965-10-22 1966-10-19 The preparation of optically active -‡-methyl--‡-amino--ß-(hydroxyphenyl)propionic acids

Family Applications Before (2)

Application Number Title Priority Date Filing Date
GB692068A Expired GB1130868A (en) 1965-10-22 1966-10-19 Alpha cyanoesters and their conversion to dicarboxylic derivatives
GB692168A Expired GB1130869A (en) 1965-10-22 1966-10-19 -‡-methyl--‡-carboalkoxy--ß-phenyl-propionic acid derivatives

Country Status (5)

Country Link
BR (1) BR6683659D0 (en)
CH (1) CH480297A (en)
FR (1) FR1502949A (en)
GB (3) GB1130868A (en)
NL (2) NL6614969A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1327294A (en) * 1971-04-30 1973-08-22 Shell Int Research Process for the preparation of alpha-anilinocarboxylic esters or nitriles

Also Published As

Publication number Publication date
FR1502949A (en) 1967-11-24
NL136594C (en)
NL6614969A (en) 1967-04-24
BR6683659D0 (en) 1973-12-04
CH480297A (en) 1969-10-31
GB1130869A (en) 1968-10-16
GB1130868A (en) 1968-10-16

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