ES330192A1 - Procedure for the synthesis of 5 beta-h-6-ceto-steroids (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the synthesis of 5 beta-h-6-ceto-steroids (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES330192A1
ES330192A1 ES0330192A ES330192A ES330192A1 ES 330192 A1 ES330192 A1 ES 330192A1 ES 0330192 A ES0330192 A ES 0330192A ES 330192 A ES330192 A ES 330192A ES 330192 A1 ES330192 A1 ES 330192A1
Authority
ES
Spain
Prior art keywords
beta
translation
synthesis
group
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0330192A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES330192A1 publication Critical patent/ES330192A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedure for the synthesis of 5beta-H-6-ketosteroids, of partial formula I ** (See formula) ** in which R1 represents a hydroxyl group with beta, free or esterified configuration, R2 represents a hydroxylic group, free, or esterified, and, when the substituent R2 has beta configuration, R1 and R2 together can also represent an alkylenedioxylic group, characterized by transposing: a) a corresponding 5alpha-H-6-ketosteroid, by energy input in the presence of catalysts or in the absence of them, or b) a corresponding 5,6-oxidesteroid, in the presence of an acid catalyst, to form a 5beta-H-ketosteroid of the partial formula I and, if desired, by subsequently saponifying the acyl radicals present, dissociating an alkylenedioxylic group or acylating free hydroxyl groups. (Machine-translation by Google Translate, not legally binding)
ES0330192A 1965-08-13 1966-08-12 Procedure for the synthesis of 5 beta-h-6-ceto-steroids (Machine-translation by Google Translate, not legally binding) Expired ES330192A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH1143065A CH467760A (en) 1965-08-13 1965-08-13 Process for the preparation of 5B-H-6-keto steroids
CH1390765 1965-10-08
CH123166 1966-01-28
CH433666 1966-03-24

Publications (1)

Publication Number Publication Date
ES330192A1 true ES330192A1 (en) 1967-09-01

Family

ID=27428125

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0330192A Expired ES330192A1 (en) 1965-08-13 1966-08-12 Procedure for the synthesis of 5 beta-h-6-ceto-steroids (Machine-translation by Google Translate, not legally binding)

Country Status (11)

Country Link
AT (1) AT268555B (en)
BE (1) BE685305A (en)
BR (1) BR6681938D0 (en)
CH (1) CH467760A (en)
DK (2) DK122664B (en)
ES (1) ES330192A1 (en)
FI (1) FI43596B (en)
GB (10) GB1145648A (en)
IL (1) IL26262A (en)
NL (1) NL6611383A (en)
SE (2) SE375536B (en)

Also Published As

Publication number Publication date
GB1145641A (en) 1969-03-19
BE685305A (en) 1967-02-10
NL6611383A (en) 1967-02-14
SE375536B (en) 1975-04-21
CH467760A (en) 1969-01-31
AT268555B (en) 1969-02-10
GB1145647A (en) 1969-03-19
GB1145646A (en) 1969-03-19
GB1145644A (en) 1969-03-19
GB1145649A (en) 1969-03-19
GB1145651A (en) 1969-03-19
SE342813B (en) 1972-02-21
GB1145650A (en) 1969-03-19
DK124479B (en) 1972-10-23
BR6681938D0 (en) 1973-12-26
GB1145643A (en) 1969-03-19
IL26262A (en) 1971-05-26
DK122664B (en) 1972-03-27
FI43596B (en) 1971-02-01
GB1145645A (en) 1969-03-19
GB1145648A (en) 1969-03-19

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