GB1142474A - Production of piperidino-butyrophenones - Google Patents
Production of piperidino-butyrophenonesInfo
- Publication number
- GB1142474A GB1142474A GB1244865A GB1244865A GB1142474A GB 1142474 A GB1142474 A GB 1142474A GB 1244865 A GB1244865 A GB 1244865A GB 1244865 A GB1244865 A GB 1244865A GB 1142474 A GB1142474 A GB 1142474A
- Authority
- GB
- United Kingdom
- Prior art keywords
- reacting
- bromobenzene
- march
- products
- addition salts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- VFLPICJWFQLLSY-UHFFFAOYSA-N 1-phenyl-2-piperidin-1-ylbutan-1-one Chemical class C=1C=CC=CC=1C(=O)C(CC)N1CCCCC1 VFLPICJWFQLLSY-UHFFFAOYSA-N 0.000 title 1
- QARVLSVVCXYDNA-UHFFFAOYSA-N bromobenzene Chemical compound BrC1=CC=CC=C1 QARVLSVVCXYDNA-UHFFFAOYSA-N 0.000 abstract 2
- YKYOUMDCQGMQQO-UHFFFAOYSA-L cadmium dichloride Chemical compound Cl[Cd]Cl YKYOUMDCQGMQQO-UHFFFAOYSA-L 0.000 abstract 2
- 150000004795 grignard reagents Chemical class 0.000 abstract 2
- 150000003053 piperidines Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- AITNMTXHTIIIBB-UHFFFAOYSA-N 1-bromo-4-fluorobenzene Chemical compound FC1=CC=C(Br)C=C1 AITNMTXHTIIIBB-UHFFFAOYSA-N 0.000 abstract 1
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 abstract 1
- YTBGIDYCSPWDSH-UHFFFAOYSA-N C=1C=CC=CC=1[Cd]C1=CC=CC=C1 Chemical class C=1C=CC=CC=1[Cd]C1=CC=CC=C1 YTBGIDYCSPWDSH-UHFFFAOYSA-N 0.000 abstract 1
- KPWJBEFBFLRCLH-UHFFFAOYSA-L Cadmium bromide Inorganic materials Br[Cd]Br KPWJBEFBFLRCLH-UHFFFAOYSA-L 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 239000011777 magnesium Substances 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Catching Or Destruction (AREA)
Priority Applications (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1244865A GB1142474A (en) | 1965-03-24 | 1965-03-24 | Production of piperidino-butyrophenones |
| BR16975165A BR6569751D0 (pt) | 1965-03-24 | 1965-05-19 | Processo para preparar cetonas basicas |
| NO16214066A NO122527B (enrdf_load_stackoverflow) | 1965-03-24 | 1966-03-16 | |
| SE350666A SE332983B (enrdf_load_stackoverflow) | 1965-03-24 | 1966-03-16 | |
| CH393666A CH478120A (de) | 1965-03-24 | 1966-03-18 | Verfahren zur Herstellung basischer Ketone mit pharmakologisch wertvollen Eigenschaften |
| ES0324501A ES324501A1 (es) | 1965-03-24 | 1966-03-22 | Procedimiento para la preparacion de butirofenonas basicas. |
| DK151266A DK129934B (da) | 1965-03-24 | 1966-03-23 | Analogifremgangsmåde til fremstilling af basiske ketoner eller syreadditionssalte deraf. |
| FR54697A FR1497478A (fr) | 1965-03-24 | 1966-03-23 | Procédé de préparation de cétones basiques |
| NL6603798A NL6603798A (enrdf_load_stackoverflow) | 1965-03-24 | 1966-03-23 | |
| FI74266A FI47765C (fi) | 1965-03-24 | 1966-03-23 | Menetelmä -(4-alkyylipiperidiino)-p-F-butyrofenonien valmistamiseksi, joilla on arvokkaita farmakologisia ominaisuuksia. |
| LU50736A LU50736A1 (enrdf_load_stackoverflow) | 1965-03-24 | 1966-03-23 | |
| BE678361D BE678361A (enrdf_load_stackoverflow) | 1965-03-24 | 1966-03-24 | |
| BE683541D BE683541A (enrdf_load_stackoverflow) | 1965-03-24 | 1966-07-01 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1244865A GB1142474A (en) | 1965-03-24 | 1965-03-24 | Production of piperidino-butyrophenones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1142474A true GB1142474A (en) | 1969-02-05 |
Family
ID=10004786
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1244865A Expired GB1142474A (en) | 1965-03-24 | 1965-03-24 | Production of piperidino-butyrophenones |
Country Status (11)
| Country | Link |
|---|---|
| BE (2) | BE678361A (enrdf_load_stackoverflow) |
| BR (1) | BR6569751D0 (enrdf_load_stackoverflow) |
| CH (1) | CH478120A (enrdf_load_stackoverflow) |
| DK (1) | DK129934B (enrdf_load_stackoverflow) |
| ES (1) | ES324501A1 (enrdf_load_stackoverflow) |
| FI (1) | FI47765C (enrdf_load_stackoverflow) |
| GB (1) | GB1142474A (enrdf_load_stackoverflow) |
| LU (1) | LU50736A1 (enrdf_load_stackoverflow) |
| NL (1) | NL6603798A (enrdf_load_stackoverflow) |
| NO (1) | NO122527B (enrdf_load_stackoverflow) |
| SE (1) | SE332983B (enrdf_load_stackoverflow) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4070473A (en) * | 1973-01-26 | 1978-01-24 | Ab Ferrosan | Piperidino-butyrophenones |
| JPS54125630A (en) * | 1978-02-22 | 1979-09-29 | Nippon Zoki Pharmaceutical Co | Novel propanone derivative*its manufacture and medical composition containing it as active component |
-
1965
- 1965-03-24 GB GB1244865A patent/GB1142474A/en not_active Expired
- 1965-05-19 BR BR16975165A patent/BR6569751D0/pt unknown
-
1966
- 1966-03-16 NO NO16214066A patent/NO122527B/no unknown
- 1966-03-16 SE SE350666A patent/SE332983B/xx unknown
- 1966-03-18 CH CH393666A patent/CH478120A/de not_active IP Right Cessation
- 1966-03-22 ES ES0324501A patent/ES324501A1/es not_active Expired
- 1966-03-23 FI FI74266A patent/FI47765C/fi active
- 1966-03-23 DK DK151266A patent/DK129934B/da unknown
- 1966-03-23 NL NL6603798A patent/NL6603798A/xx unknown
- 1966-03-23 LU LU50736A patent/LU50736A1/xx unknown
- 1966-03-24 BE BE678361D patent/BE678361A/xx not_active IP Right Cessation
- 1966-07-01 BE BE683541D patent/BE683541A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BE683541A (enrdf_load_stackoverflow) | 1966-12-16 |
| DK129934C (enrdf_load_stackoverflow) | 1975-05-12 |
| NL6603798A (enrdf_load_stackoverflow) | 1966-09-26 |
| SE332983B (enrdf_load_stackoverflow) | 1971-03-01 |
| NO122527B (enrdf_load_stackoverflow) | 1971-07-12 |
| CH478120A (de) | 1969-09-15 |
| ES324501A1 (es) | 1967-05-01 |
| LU50736A1 (enrdf_load_stackoverflow) | 1966-05-23 |
| FI47765B (enrdf_load_stackoverflow) | 1973-11-30 |
| BR6569751D0 (pt) | 1973-08-16 |
| DK129934B (da) | 1974-12-02 |
| BE678361A (enrdf_load_stackoverflow) | 1966-09-01 |
| FI47765C (fi) | 1974-03-11 |
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