GB1139940A - Oxazole derivatives - Google Patents
Oxazole derivativesInfo
- Publication number
- GB1139940A GB1139940A GB4378666A GB4378666A GB1139940A GB 1139940 A GB1139940 A GB 1139940A GB 4378666 A GB4378666 A GB 4378666A GB 4378666 A GB4378666 A GB 4378666A GB 1139940 A GB1139940 A GB 1139940A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- coor
- reacting
- dialkylaminoalkyl
- appropriate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000007978 oxazole derivatives Chemical class 0.000 title abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 15
- 150000001875 compounds Chemical class 0.000 abstract 8
- 125000004985 dialkyl amino alkyl group Chemical group 0.000 abstract 5
- 230000007062 hydrolysis Effects 0.000 abstract 4
- 238000006460 hydrolysis reaction Methods 0.000 abstract 4
- 125000005078 alkoxycarbonylalkyl group Chemical group 0.000 abstract 3
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 3
- 150000002148 esters Chemical class 0.000 abstract 3
- 125000005843 halogen group Chemical group 0.000 abstract 3
- 150000002825 nitriles Chemical class 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- DLFVBJFMPXGRIB-UHFFFAOYSA-N Acetamide Chemical compound CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 abstract 2
- 150000001408 amides Chemical class 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 125000004181 carboxyalkyl group Chemical group 0.000 abstract 2
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 150000003254 radicals Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
- 125000004454 (C1-C6) alkoxycarbonyl group Chemical group 0.000 abstract 1
- FKJSFKCZZIXQIP-UHFFFAOYSA-N 2-bromo-1-(4-bromophenyl)ethanone Chemical compound BrCC(=O)C1=CC=C(Br)C=C1 FKJSFKCZZIXQIP-UHFFFAOYSA-N 0.000 abstract 1
- SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical compound [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 abstract 1
- KUNURROGBCFQQW-UHFFFAOYSA-N 4-(4-bromophenyl)-2-methyl-1,3-oxazole Chemical compound O1C(C)=NC(C=2C=CC(Br)=CC=2)=C1 KUNURROGBCFQQW-UHFFFAOYSA-N 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 150000004703 alkoxides Chemical class 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 230000002152 alkylating effect Effects 0.000 abstract 1
- 125000005997 bromomethyl group Chemical group 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- KXZJHVJKXJLBKO-UHFFFAOYSA-N chembl1408157 Chemical compound N=1C2=CC=CC=C2C(C(=O)O)=CC=1C1=CC=C(O)C=C1 KXZJHVJKXJLBKO-UHFFFAOYSA-N 0.000 abstract 1
- 150000004678 hydrides Chemical class 0.000 abstract 1
- 150000007529 inorganic bases Chemical class 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 239000011591 potassium Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 229910000033 sodium borohydride Inorganic materials 0.000 abstract 1
- 239000012279 sodium borohydride Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23F—NON-MECHANICAL REMOVAL OF METALLIC MATERIAL FROM SURFACE; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL; MULTI-STEP PROCESSES FOR SURFACE TREATMENT OF METALLIC MATERIAL INVOLVING AT LEAST ONE PROCESS PROVIDED FOR IN CLASS C23 AND AT LEAST ONE PROCESS COVERED BY SUBCLASS C21D OR C22F OR CLASS C25
- C23F11/00—Inhibiting corrosion of metallic material by applying inhibitors to the surface in danger of corrosion or adding them to the corrosive agent
- C23F11/04—Inhibiting corrosion of metallic material by applying inhibitors to the surface in danger of corrosion or adding them to the corrosive agent in markedly acid liquids
-
- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23G—CLEANING OR DE-GREASING OF METALLIC MATERIAL BY CHEMICAL METHODS OTHER THAN ELECTROLYSIS
- C23G1/00—Cleaning or pickling metallic material with solutions or molten salts
- C23G1/02—Cleaning or pickling metallic material with solutions or molten salts with acid solutions
- C23G1/04—Cleaning or pickling metallic material with solutions or molten salts with acid solutions using inhibitors
- C23G1/06—Cleaning or pickling metallic material with solutions or molten salts with acid solutions using inhibitors organic inhibitors
- C23G1/068—Cleaning or pickling metallic material with solutions or molten salts with acid solutions using inhibitors organic inhibitors compounds containing a C=C bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Metallurgy (AREA)
- Mechanical Engineering (AREA)
- Materials Engineering (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Priority Applications (25)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US504056A US3401120A (en) | 1965-10-23 | 1965-10-23 | Corrosion inhibitors |
| GB4378666A GB1139940A (en) | 1966-09-30 | 1966-09-30 | Oxazole derivatives |
| GB43771/66A GB1097490A (en) | 1965-10-23 | 1966-09-30 | Improvements in or relating to corrosion-inhibitors |
| DE19661521764 DE1521764A1 (de) | 1965-10-23 | 1966-10-14 | Korrosionsinhibitoren |
| FR80936A FR1505495A (fr) | 1965-10-23 | 1966-10-21 | Inhibiteurs de corrosion |
| US664941A US3470195A (en) | 1965-10-23 | 1967-09-01 | Phenyl and benzyl oxazole acetic acid compounds |
| DE19671695289 DE1695289A1 (de) | 1965-10-23 | 1967-09-11 | Oxazolderivate und Verfahren zu deren Herstellung |
| SE03326/69A SE335130B (enrdf_load_stackoverflow) | 1965-10-23 | 1967-09-20 | |
| SE03324/69A SE334890B (enrdf_load_stackoverflow) | 1965-10-23 | 1967-09-20 | |
| SE03325/69A SE335129B (enrdf_load_stackoverflow) | 1965-10-23 | 1967-09-20 | |
| SE12965/67A SE313569B (enrdf_load_stackoverflow) | 1965-10-23 | 1967-09-20 | |
| DK469167AA DK122766B (da) | 1965-10-23 | 1967-09-20 | Analogifremgangsmåde til fremstilling af oksazolalkansyrederivater. |
| SE03323/69A SE334889B (enrdf_load_stackoverflow) | 1965-10-23 | 1967-09-20 | |
| NL6713229A NL6713229A (enrdf_load_stackoverflow) | 1965-10-23 | 1967-09-28 | |
| FR122829A FR1544224A (fr) | 1965-10-23 | 1967-09-29 | Dérivés d'oxazole et procédé pour leur fabrication |
| CH275470A CH535251A (de) | 1965-10-23 | 1967-09-29 | Alkylierungsverfahren zur Herstellung von Oxazolderivaten |
| CH416070A CH526574A (de) | 1965-10-23 | 1967-09-29 | Verfahren zur Herstellung von Oxazolyl-alkancarbonsäureamiden |
| CH83871A CH512505A (de) | 1965-10-23 | 1967-09-29 | Verfahren zur Herstellung von Oxazolderivaten |
| CH275370A CH535250A (de) | 1965-10-23 | 1967-09-29 | Verfahren zur Herstellung von Estern von Oxazolyl-alkansäuren |
| CH1868171A CH527209A (de) | 1965-10-23 | 1967-09-29 | Verfahren zur Herstellung von Oxazolyl-alkancarbonsäureamiden |
| BE704545D BE704545A (enrdf_load_stackoverflow) | 1965-10-23 | 1967-09-29 | |
| CH1361967A CH507974A (de) | 1965-10-23 | 1967-09-29 | Verfahren zur Herstellung von Oxazolderivaten |
| JP8595569A JPS4639856B1 (enrdf_load_stackoverflow) | 1966-09-30 | 1967-09-30 | |
| JP8595669A JPS4641542B1 (enrdf_load_stackoverflow) | 1966-09-30 | 1967-09-30 | |
| FR134472A FR6946M (enrdf_load_stackoverflow) | 1965-10-23 | 1967-12-29 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4378666A GB1139940A (en) | 1966-09-30 | 1966-09-30 | Oxazole derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1139940A true GB1139940A (en) | 1969-01-15 |
Family
ID=10430300
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4378666A Expired GB1139940A (en) | 1965-10-23 | 1966-09-30 | Oxazole derivatives |
Country Status (2)
| Country | Link |
|---|---|
| JP (2) | JPS4639856B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1139940A (enrdf_load_stackoverflow) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0094612A3 (en) * | 1982-05-19 | 1985-01-23 | Tanabe Seiyaku Co., Ltd. | Novel alkyloxazolylacetic acid derivative, processes for preparation and pharmaceutical compositions containing same |
| EP0440183A1 (en) * | 1990-02-01 | 1991-08-07 | Takeda Chemical Industries, Ltd. | Oxazole compounds, their production and use |
| US6767918B2 (en) * | 1996-11-22 | 2004-07-27 | Athena Neurosciences, Inc. | N-(aryl/heteroarylacetyl) amino acid esters, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
| WO2006108493A1 (en) * | 2005-04-11 | 2006-10-19 | Dsm Fine Chemicals Austria Nfg Gmbh & Co Kg | Process for preparing oxazole carboxylic esters |
| WO2006108491A1 (en) * | 2005-04-11 | 2006-10-19 | Dsm Fine Chemicals Austria Nfg Gmbh & Co Kg | Improved process for preparing oxazole nitriles |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW311136B (enrdf_load_stackoverflow) * | 1990-11-30 | 1997-07-21 | Otsuka Pharma Co Ltd |
-
1966
- 1966-09-30 GB GB4378666A patent/GB1139940A/en not_active Expired
-
1967
- 1967-09-30 JP JP8595569A patent/JPS4639856B1/ja active Pending
- 1967-09-30 JP JP8595669A patent/JPS4641542B1/ja active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0094612A3 (en) * | 1982-05-19 | 1985-01-23 | Tanabe Seiyaku Co., Ltd. | Novel alkyloxazolylacetic acid derivative, processes for preparation and pharmaceutical compositions containing same |
| EP0440183A1 (en) * | 1990-02-01 | 1991-08-07 | Takeda Chemical Industries, Ltd. | Oxazole compounds, their production and use |
| US6767918B2 (en) * | 1996-11-22 | 2004-07-27 | Athena Neurosciences, Inc. | N-(aryl/heteroarylacetyl) amino acid esters, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
| WO2006108493A1 (en) * | 2005-04-11 | 2006-10-19 | Dsm Fine Chemicals Austria Nfg Gmbh & Co Kg | Process for preparing oxazole carboxylic esters |
| WO2006108491A1 (en) * | 2005-04-11 | 2006-10-19 | Dsm Fine Chemicals Austria Nfg Gmbh & Co Kg | Improved process for preparing oxazole nitriles |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS4639856B1 (enrdf_load_stackoverflow) | 1971-11-24 |
| JPS4641542B1 (enrdf_load_stackoverflow) | 1971-12-08 |
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