GB1121922A - Pyrimidine derivatives - Google Patents
Pyrimidine derivativesInfo
- Publication number
- GB1121922A GB1121922A GB27083/66A GB2708366A GB1121922A GB 1121922 A GB1121922 A GB 1121922A GB 27083/66 A GB27083/66 A GB 27083/66A GB 2708366 A GB2708366 A GB 2708366A GB 1121922 A GB1121922 A GB 1121922A
- Authority
- GB
- United Kingdom
- Prior art keywords
- radical
- ethyl
- compound
- chlorophenyl
- ylacetate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- G—PHYSICS
- G11—INFORMATION STORAGE
- G11B—INFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
- G11B15/00—Driving, starting or stopping record carriers of filamentary or web form; Driving both such record carriers and heads; Guiding such record carriers or containers therefor; Control thereof; Control of operating function
- G11B15/18—Driving; Starting; Stopping; Arrangements for control or regulation thereof
- G11B15/20—Moving record carrier backwards or forwards by finite amounts, i.e. backspacing, forward spacing
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Braking Arrangements (AREA)
- Registering, Tensioning, Guiding Webs, And Rollers Therefor (AREA)
- Tension Adjustment In Filamentary Materials (AREA)
Priority Applications (14)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB27083/66A GB1121922A (en) | 1966-06-17 | 1966-06-17 | Pyrimidine derivatives |
| US638726A US3502673A (en) | 1966-06-17 | 1967-05-16 | Aryl-pyrimidine-alkanoic acid derivatives |
| AT531067A AT273136B (de) | 1966-06-17 | 1967-06-07 | Verfahren zur Herstellung von neuen Alkoxypyrimidinderivaten und von deren Salzen |
| DK303767A DK115917B (da) | 1966-06-17 | 1967-06-09 | Analogifremgangsmåde til fremstilling af terapeutisk aktive alkoxypyrimidineddikesyrederivater. |
| GB27083/67A GB1157157A (en) | 1966-06-17 | 1967-06-12 | Improvements in or relating to Tape Recorders |
| NL6708449A NL6708449A (cg-RX-API-DMAC10.html) | 1966-06-17 | 1967-06-16 | |
| BE700109D BE700109A (cg-RX-API-DMAC10.html) | 1966-06-17 | 1967-06-16 | |
| ES341927A ES341927A1 (es) | 1966-06-17 | 1967-06-17 | Procedimiento para preparar derivados de la pirimidina. |
| FR121250A FR7509M (cg-RX-API-DMAC10.html) | 1966-06-17 | 1967-09-15 | |
| US736137A US3554421A (en) | 1966-06-17 | 1968-06-11 | Incremental tape drive |
| FR1571589D FR1571589A (cg-RX-API-DMAC10.html) | 1966-06-17 | 1968-06-11 | |
| DE19681774407 DE1774407A1 (de) | 1966-06-17 | 1968-06-12 | Bandgeraet |
| DK416868A DK117836B (da) | 1966-06-17 | 1968-08-29 | Analogifremgangsmåde til fremstilling af terapeutisk aktive pyrimidineddikesyrer. |
| US871335A US3592895A (en) | 1966-06-17 | 1969-10-24 | Pyrimidine derivatives as anti-inflammatory,analgesic and antipyretic agents |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB27083/66A GB1121922A (en) | 1966-06-17 | 1966-06-17 | Pyrimidine derivatives |
| GB27083/67A GB1157157A (en) | 1966-06-17 | 1967-06-12 | Improvements in or relating to Tape Recorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1121922A true GB1121922A (en) | 1968-07-31 |
Family
ID=26258620
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB27083/66A Expired GB1121922A (en) | 1966-06-17 | 1966-06-17 | Pyrimidine derivatives |
| GB27083/67A Expired GB1157157A (en) | 1966-06-17 | 1967-06-12 | Improvements in or relating to Tape Recorders |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB27083/67A Expired GB1157157A (en) | 1966-06-17 | 1967-06-12 | Improvements in or relating to Tape Recorders |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US3502673A (cg-RX-API-DMAC10.html) |
| BE (1) | BE700109A (cg-RX-API-DMAC10.html) |
| DE (1) | DE1774407A1 (cg-RX-API-DMAC10.html) |
| FR (2) | FR7509M (cg-RX-API-DMAC10.html) |
| GB (2) | GB1121922A (cg-RX-API-DMAC10.html) |
| NL (1) | NL6708449A (cg-RX-API-DMAC10.html) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2053012A1 (cg-RX-API-DMAC10.html) * | 1969-06-25 | 1971-04-16 | Merck & Co Inc | |
| DE2252822B2 (de) * | 1971-10-28 | 1975-09-18 | Delalande S.A., Courbevoie, Hauts- De-Seine (Frankreich) | 6-pyrimidinyl-acethydroxamsaeuren |
| US5136080A (en) * | 1989-12-04 | 1992-08-04 | Burroughs Wellcome Co. | Nitrile compounds |
| WO2008127727A1 (en) * | 2007-04-13 | 2008-10-23 | Kinex Pharmaceuticals, Llc | Biaryl compositions and methods for modulating a kinase cascade |
| US8124605B2 (en) | 2007-07-06 | 2012-02-28 | Kinex Pharmaceuticals, Llc | Compositions and methods for modulating a kinase cascade |
| US9926273B2 (en) | 2012-08-30 | 2018-03-27 | Athenex, Inc. | Composition and methods for modulating a kinase cascade |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1217925A (en) * | 1968-06-14 | 1971-01-06 | Ici Ltd | Process for manufacture of phenyl-heterocyclic-acetic acid derivatives |
| US3890350A (en) * | 1970-11-09 | 1975-06-17 | Sandoz Ag | 3-Amino-2-(methylenedioxyphenyl)-acroleins |
| US3957998A (en) * | 1972-03-06 | 1976-05-18 | Bayer Aktiengesellschaft | Use of 2,6-diamino-4-substituted-1,4-dihydropyridine-3,5-dicarboxylic acid esters for effecting coronary vessel dilation and treating hypertension |
| JPS4946710A (cg-RX-API-DMAC10.html) * | 1972-09-08 | 1974-05-04 | ||
| US4248618A (en) * | 1977-05-06 | 1981-02-03 | Ici Australia Limited | Derivatives of (pyrimidyloxy)phenoxy-alkanecarboxylic acid and herbicidal compositions thereof |
| US4214937A (en) * | 1978-06-08 | 1980-07-29 | Dennison Manufacturing Company | Application of indicia to articles |
| US5238907A (en) * | 1989-10-09 | 1993-08-24 | Schering Aktiengesellschaft | Substituted 2-pyrimidinyl-acetic acid derivatives, and their use as herbicides, fungicides and plant growth regulators |
| DE3934020A1 (de) * | 1989-10-09 | 1991-04-18 | Schering Ag | Substituierte 2-pyrimidinyl- und 2-triazinylessigsaeurederivate, verfahren zu ihrer herstellung und ihre verwendung als mittel mit herbizider, fungizider und pflanzenwachstumsregulierender wirkung |
| US5957360A (en) * | 1998-01-16 | 1999-09-28 | International Business Machines Corporation | System and method for transporting and clamping flexible film structures |
| AR029489A1 (es) * | 2000-03-10 | 2003-07-02 | Euro Celtique Sa | Piridinas, pirimidinas, pirazinas, triazinas sustituidas por arilo, composiciones farmaceuticas y el uso de las mismas para la manufactura de un medicamento |
| KR20020011986A (ko) * | 2000-03-16 | 2002-02-09 | 해피 페너 ; 해리 에이치. 페너 2세 | 5-치환된 아릴피리미딘 |
| GB0021494D0 (en) | 2000-09-01 | 2000-10-18 | Glaxo Group Ltd | Chemical comkpounds |
| GB0112802D0 (en) * | 2001-05-25 | 2001-07-18 | Glaxo Group Ltd | Pyrimidine derivatives |
| GB0112810D0 (en) * | 2001-05-25 | 2001-07-18 | Glaxo Group Ltd | Pyrimidine derivatives |
| GB0112803D0 (en) * | 2001-05-25 | 2001-07-18 | Glaxo Group Ltd | Pyrimidine derivatives |
| GB0119477D0 (en) * | 2001-08-09 | 2001-10-03 | Glaxo Group Ltd | Pyrimidine derivatives |
| AR037233A1 (es) * | 2001-09-07 | 2004-11-03 | Euro Celtique Sa | Piridinas aril sustituidas, composiciones farmaceuticas y el uso de dichos compuestos para la elaboracion de un medicamento |
| AR036873A1 (es) * | 2001-09-07 | 2004-10-13 | Euro Celtique Sa | Piridinas aril sustituidas a, composiciones farmaceuticas y el uso de las mismas para la preparacion de un medicamento |
| US7235560B2 (en) * | 2002-08-19 | 2007-06-26 | Glaxo Group Limited | Pyrimidine derivative as selective COX-2 inhibitors |
| GB0221443D0 (en) | 2002-09-16 | 2002-10-23 | Glaxo Group Ltd | Pyridine derivates |
| GB0227443D0 (en) * | 2002-11-25 | 2002-12-31 | Glaxo Group Ltd | Pyrimidine derivatives |
| GB0319037D0 (en) * | 2003-08-13 | 2003-09-17 | Glaxo Group Ltd | 7-Azaindole Derivatives |
| GB0908394D0 (en) | 2009-05-15 | 2009-06-24 | Univ Leuven Kath | Novel viral replication inhibitors |
| GB0913636D0 (en) * | 2009-08-05 | 2009-09-16 | Univ Leuven Kath | Novel viral replication inhibitors |
| EP2640705A2 (en) | 2010-11-15 | 2013-09-25 | Katholieke Universiteit Leuven | Novel antiviral compounds |
| US11091451B2 (en) * | 2016-12-05 | 2021-08-17 | Raze Therapeutics, Inc. | SHMT inhibitors and uses thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2858131A (en) * | 1955-04-25 | 1958-10-28 | Burroughs Corp | Tape metering device |
| US3225047A (en) * | 1964-02-24 | 1965-12-21 | Bristol Myers Co | N,n'-bis(pyrimidine-5-acetyl)ethylene diamines |
| US3326437A (en) * | 1965-04-16 | 1967-06-20 | Atvidabergs Ind Ab | Device for the stepwise feed of bandshaped record supports |
| US3454206A (en) * | 1967-11-13 | 1969-07-08 | Ryan Aeronautical Co | Electrostrictive incremental film drive |
-
1966
- 1966-06-17 GB GB27083/66A patent/GB1121922A/en not_active Expired
-
1967
- 1967-05-16 US US638726A patent/US3502673A/en not_active Expired - Lifetime
- 1967-06-12 GB GB27083/67A patent/GB1157157A/en not_active Expired
- 1967-06-16 BE BE700109D patent/BE700109A/xx unknown
- 1967-06-16 NL NL6708449A patent/NL6708449A/xx unknown
- 1967-09-15 FR FR121250A patent/FR7509M/fr not_active Expired
-
1968
- 1968-06-11 FR FR1571589D patent/FR1571589A/fr not_active Expired
- 1968-06-11 US US736137A patent/US3554421A/en not_active Expired - Lifetime
- 1968-06-12 DE DE19681774407 patent/DE1774407A1/de active Pending
-
1969
- 1969-10-24 US US871335A patent/US3592895A/en not_active Expired - Lifetime
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2053012A1 (cg-RX-API-DMAC10.html) * | 1969-06-25 | 1971-04-16 | Merck & Co Inc | |
| DE2252822B2 (de) * | 1971-10-28 | 1975-09-18 | Delalande S.A., Courbevoie, Hauts- De-Seine (Frankreich) | 6-pyrimidinyl-acethydroxamsaeuren |
| DE2252822C3 (de) * | 1971-10-28 | 1976-05-06 | Delalande Sa | 6-pyrimidinyl-acethydroxamsaeuren |
| US5136080A (en) * | 1989-12-04 | 1992-08-04 | Burroughs Wellcome Co. | Nitrile compounds |
| WO2008127727A1 (en) * | 2007-04-13 | 2008-10-23 | Kinex Pharmaceuticals, Llc | Biaryl compositions and methods for modulating a kinase cascade |
| US8124605B2 (en) | 2007-07-06 | 2012-02-28 | Kinex Pharmaceuticals, Llc | Compositions and methods for modulating a kinase cascade |
| US9926273B2 (en) | 2012-08-30 | 2018-03-27 | Athenex, Inc. | Composition and methods for modulating a kinase cascade |
| US10106505B2 (en) | 2012-08-30 | 2018-10-23 | Athenex, Inc. | Composition and methods for modulating a kinase cascade |
Also Published As
| Publication number | Publication date |
|---|---|
| FR7509M (cg-RX-API-DMAC10.html) | 1969-12-15 |
| NL6708449A (cg-RX-API-DMAC10.html) | 1967-12-18 |
| BE700109A (cg-RX-API-DMAC10.html) | 1967-12-18 |
| FR1571589A (cg-RX-API-DMAC10.html) | 1969-06-20 |
| GB1157157A (en) | 1969-07-02 |
| US3554421A (en) | 1971-01-12 |
| DE1774407A1 (de) | 1971-07-15 |
| US3592895A (en) | 1971-07-13 |
| US3502673A (en) | 1970-03-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1121922A (en) | Pyrimidine derivatives | |
| ES2587447T3 (es) | Método de tratamiento de nefropatía inducida por medio de contraste | |
| EP1836169B1 (en) | Compositions and methods of treating cell proliferation disorders | |
| Bergman et al. | Synthesis of Chrysogine, a Metabolite of Penicillium chrysogenum and some related 2-substituted 4-(3H)-Quinazolinones | |
| EP0340905B1 (en) | Fused pyrimidines, their production and use | |
| ES2305090T3 (es) | Esteres de acido 4-alcoxi-ciclohexano-1-aminocarboxilico y procedimiento para su preparacion. | |
| SK54195A3 (en) | N-(2-amino-4,6-dichlorpyrimidine-5-yl) formamide and method of its production, dichloropyrimidine and method of its production | |
| Taylor et al. | A simple aza wittig‐mediated pyrimidine annulation reaction | |
| CA2582492A1 (en) | Novel pyrimidine derivatives and their use | |
| CN111039876A (zh) | 一种4-氨基-2,6-二甲氧基嘧啶的制备方法 | |
| Saettone | Reactions of 3, 4-Disubstituted 4-Oxazolin-2-ones. I. A Novel Route to 1, 3, 5-Trisubstituted Hydantoins | |
| KATOH et al. | Ring transformation reactions of 1-substituted 2 (1H)-pyrimidinones and related compounds with active methylene compounds | |
| US3920655A (en) | Nitroimidazolyl benzoquinazolines | |
| SK393192A3 (en) | N-5-protecting 2,5-diamino-4,6-dichloropyrimidines and method of their preparation | |
| REIDER et al. | STUDIES IN THE PYRIDINE SERIES. V. REACTIONS INVOLVING THE ORTHO EFFECT IN CERTAIN β, γ SUBSTITUTED PYRIDINES | |
| Hagmann et al. | Chemistry of 2-substituted pyrimidines. Studies directed toward the synthesis of the pyrimidine moiety of bleomycin | |
| Owton et al. | Synthesis of 6-tert-butyl-2-arylpyridines | |
| US6291674B2 (en) | Process for preparing alkoxypyrazine derivatives | |
| Uchida et al. | Reactions of N-Acylaminoacetamidine with 1, 3-Bifunctional Compounds | |
| GB1107806A (en) | ª‡-aliphatic carboxylic acid derivatives | |
| GB1226981A (cg-RX-API-DMAC10.html) | ||
| MORITA et al. | Synthesis and some reactions of 6-(2-hydroxyphenyl)-2-thiouracils | |
| Batty et al. | Synthesis and exchange reactions of 5‐alkyl‐2‐oxo‐6‐thioxo‐1, 2, 3, 6‐hexahydropyrimidine‐4‐carboxylic acids | |
| SENDA et al. | Pyrimidine Derivatives and Related Compounds. XVII. Hydrolysis of 5-Cyanouracil Derivatives | |
| CN101423524B (zh) | 二谷氨酸酯衍生物及其在培美曲塞制备中的应用 |