GB1108758A - Substituted-17ª‡-buta-1',3'-diynyl-steroids - Google Patents
Substituted-17ª‡-buta-1',3'-diynyl-steroidsInfo
- Publication number
- GB1108758A GB1108758A GB4766/66A GB476666A GB1108758A GB 1108758 A GB1108758 A GB 1108758A GB 4766/66 A GB4766/66 A GB 4766/66A GB 476666 A GB476666 A GB 476666A GB 1108758 A GB1108758 A GB 1108758A
- Authority
- GB
- United Kingdom
- Prior art keywords
- diynyl
- bromoethynyl
- steroids
- androst
- octa
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003431 steroids Chemical class 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- -1 ethynyl compound Chemical class 0.000 abstract 3
- HSFWRNGVRCDJHI-UHFFFAOYSA-N alpha-acetylene Natural products C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 abstract 2
- 230000031709 bromination Effects 0.000 abstract 2
- 238000005893 bromination reaction Methods 0.000 abstract 2
- 230000003637 steroidlike Effects 0.000 abstract 2
- FCDCGVBZGPWAKS-SKKJJERVSA-N 2-[[(8R,9S,10R,13R,14S,17S)-17-ethynyl-10-methyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-13-yl]methoxy]oxane Chemical compound O1C(CCCC1)OC[C@@]12[C@@H](CC[C@H]1[C@@H]1CC=C3CCCC[C@]3(C)[C@H]1CC2)C#C FCDCGVBZGPWAKS-SKKJJERVSA-N 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- RJCQBQGAPKAMLL-UHFFFAOYSA-N bromotrifluoromethane Chemical compound FC(F)(F)Br RJCQBQGAPKAMLL-UHFFFAOYSA-N 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 125000002534 ethynyl group Chemical group [H]C#C* 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 150000002688 maleic acid derivatives Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4766/66A GB1108758A (en) | 1966-02-03 | 1966-02-03 | Substituted-17ª‡-buta-1',3'-diynyl-steroids |
| US612081A US3463797A (en) | 1966-02-03 | 1967-01-27 | Substituted - 17alpha - buta - 1',3'-diynyl-17beta-hydroxy(17beta-alkoxy)-steroids and process for preparation thereof |
| FR92929A FR1511740A (fr) | 1966-02-03 | 1967-01-30 | Nouveaux stéroïdes substitués et leur procédé de préparation |
| BE693482D BE693482A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1966-02-03 | 1967-02-01 | |
| DE19671618088 DE1618088C3 (de) | 1966-02-03 | 1967-02-01 | Verfahren zur Herstellung von 17alpha-Buta-1 ',3'-diinylsteroiden sowie substituierte 17alpha-Buta-1 ',3'diinylsteroide |
| CH162067A CH500956A (de) | 1966-02-03 | 1967-02-03 | Verfahren zur Herstellung von neuen Steroidverbindungen |
| NL6701688A NL6701688A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1966-02-03 | 1967-02-03 | |
| DK64671AA DK124752B (da) | 1966-02-03 | 1971-02-12 | Fremgangsmåde til fremstilling af 4'-subtituerede 17α-buta-1',3'-diynyl-17β-hydroksy-steroider eller alkylætere deraf. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4766/66A GB1108758A (en) | 1966-02-03 | 1966-02-03 | Substituted-17ª‡-buta-1',3'-diynyl-steroids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1108758A true GB1108758A (en) | 1968-04-03 |
Family
ID=9783393
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4766/66A Expired GB1108758A (en) | 1966-02-03 | 1966-02-03 | Substituted-17ª‡-buta-1',3'-diynyl-steroids |
Country Status (7)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3463797A (en) * | 1966-02-03 | 1969-08-26 | British Drug Houses Ltd | Substituted - 17alpha - buta - 1',3'-diynyl-17beta-hydroxy(17beta-alkoxy)-steroids and process for preparation thereof |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1307360A (en) * | 1969-05-16 | 1973-02-21 | Bdh Pharmaceuticals Ltd | Substituted 17alpha-penta-1,3-diynyl steroids |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB961502A (en) * | 1962-02-02 | 1964-06-24 | British Drug Houses Ltd | 17ª‡-butadiynyl-17ª‰-hydroxy steroids |
| GB1108758A (en) * | 1966-02-03 | 1968-04-03 | British Drug Houses Ltd | Substituted-17ª‡-buta-1',3'-diynyl-steroids |
-
1966
- 1966-02-03 GB GB4766/66A patent/GB1108758A/en not_active Expired
-
1967
- 1967-01-27 US US612081A patent/US3463797A/en not_active Expired - Lifetime
- 1967-01-30 FR FR92929A patent/FR1511740A/fr not_active Expired
- 1967-02-01 BE BE693482D patent/BE693482A/xx unknown
- 1967-02-03 NL NL6701688A patent/NL6701688A/xx unknown
- 1967-02-03 CH CH162067A patent/CH500956A/de not_active IP Right Cessation
-
1971
- 1971-02-12 DK DK64671AA patent/DK124752B/da unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3463797A (en) * | 1966-02-03 | 1969-08-26 | British Drug Houses Ltd | Substituted - 17alpha - buta - 1',3'-diynyl-17beta-hydroxy(17beta-alkoxy)-steroids and process for preparation thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| BE693482A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1967-07-17 |
| US3463797A (en) | 1969-08-26 |
| DK124752B (da) | 1972-11-20 |
| DE1618088A1 (de) | 1970-10-29 |
| DE1618088B2 (de) | 1976-01-02 |
| FR1511740A (fr) | 1968-02-02 |
| NL6701688A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1967-08-04 |
| CH500956A (de) | 1970-12-31 |
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