GB1100915A - Production of 3-(p-aminobenzenesulphonamido)-1,2,5-thiadiazole and its acyl derivatives - Google Patents

Production of 3-(p-aminobenzenesulphonamido)-1,2,5-thiadiazole and its acyl derivatives

Info

Publication number
GB1100915A
GB1100915A GB536165A GB536165A GB1100915A GB 1100915 A GB1100915 A GB 1100915A GB 536165 A GB536165 A GB 536165A GB 536165 A GB536165 A GB 536165A GB 1100915 A GB1100915 A GB 1100915A
Authority
GB
United Kingdom
Prior art keywords
thiadiazole
chloro
aminobenzenesulphonamido
sulphanilamide
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB536165A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB1100915A publication Critical patent/GB1100915A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/101,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Sulphanilamide compounds of the formula <FORM:1100915/C2/1> wherein R is hydrogen or a C1-6 alkanoyl or a benzoyl radical are prepared by reacting 3 - chloro - 1,2,5 - thiadiazole with sulphanilamide or a C1-6 alkanoyl or benzoyl sulphanilamide in the presence of an acid-binding agent such as pyridine or a -picoline. The 3-chloro-1,2,5-thiadiazole may be prepared by hydrolysing 3 - chloro - 4 - cyano - 1,2,5 - thiadiazole with strong mineral acid to give 3-chloro-1,2,5-thiadiazole-4-carboxylic acid which is then decarboxylated by heating, suitably by refluxing in o-dichlorobenzene.
GB536165A 1964-03-18 1965-02-08 Production of 3-(p-aminobenzenesulphonamido)-1,2,5-thiadiazole and its acyl derivatives Expired GB1100915A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35299264A 1964-03-18 1964-03-18

Publications (1)

Publication Number Publication Date
GB1100915A true GB1100915A (en) 1968-01-24

Family

ID=23387296

Family Applications (2)

Application Number Title Priority Date Filing Date
GB536165A Expired GB1100915A (en) 1964-03-18 1965-02-08 Production of 3-(p-aminobenzenesulphonamido)-1,2,5-thiadiazole and its acyl derivatives
GB3641867A Expired GB1103410A (en) 1964-03-18 1965-02-08 Preparation of 3-amino-1,2,5-thiadiazole

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB3641867A Expired GB1103410A (en) 1964-03-18 1965-02-08 Preparation of 3-amino-1,2,5-thiadiazole

Country Status (8)

Country Link
BR (1) BR6567736D0 (en)
CH (1) CH460029A (en)
DE (1) DE1595922A1 (en)
ES (1) ES311024A1 (en)
FR (1) FR1433642A (en)
GB (2) GB1100915A (en)
IL (1) IL22850A (en)
NL (1) NL6503440A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL189197C (en) * 1979-09-04 1993-02-01 Bristol Myers Squibb Co 3,4-SUBSTITUTED-1,2,5-THIADIAZOLO-1-OXIDES AND 1,1-DIOXIDES, PREPARATION THEREOF, AND PHARMACEUTICAL PREPARATIONS.
ZA805250B (en) * 1979-09-04 1981-09-30 Bristol Myers Co Chemical compounds

Also Published As

Publication number Publication date
BR6567736D0 (en) 1973-08-07
FR1433642A (en) 1966-04-01
DE1595922A1 (en) 1970-02-12
ES311024A1 (en) 1965-07-01
GB1103410A (en) 1968-02-14
NL6503440A (en) 1965-09-20
CH460029A (en) 1968-07-31
IL22850A (en) 1968-12-26

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