GB1099789A - A novel imidazole derivative and a process for the preparation thereof - Google Patents

A novel imidazole derivative and a process for the preparation thereof

Info

Publication number
GB1099789A
GB1099789A GB32761/67A GB3276167A GB1099789A GB 1099789 A GB1099789 A GB 1099789A GB 32761/67 A GB32761/67 A GB 32761/67A GB 3276167 A GB3276167 A GB 3276167A GB 1099789 A GB1099789 A GB 1099789A
Authority
GB
United Kingdom
Prior art keywords
preparation
imidazole derivative
novel imidazole
novel
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB32761/67A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB1099789A publication Critical patent/GB1099789A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C07D233/92—Nitro radicals attached in position 4 or 5
    • C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/68—Halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C07D233/92—Nitro radicals attached in position 4 or 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
GB32761/67A 1965-05-19 1966-05-13 A novel imidazole derivative and a process for the preparation thereof Expired GB1099789A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45721265A 1965-05-19 1965-05-19
US76890868A 1968-10-18 1968-10-18

Publications (1)

Publication Number Publication Date
GB1099789A true GB1099789A (en) 1968-01-17

Family

ID=27038516

Family Applications (3)

Application Number Title Priority Date Filing Date
GB32761/67A Expired GB1099789A (en) 1965-05-19 1966-05-13 A novel imidazole derivative and a process for the preparation thereof
GB32760/67A Expired GB1099788A (en) 1965-05-19 1966-05-13 Novel imidazole derivatives and a process for the preparation thereof
GB21427/66A Expired GB1099787A (en) 1965-05-19 1966-05-13 Novel nitro-imidazole derivatives and the manufacture thereof

Family Applications After (2)

Application Number Title Priority Date Filing Date
GB32760/67A Expired GB1099788A (en) 1965-05-19 1966-05-13 Novel imidazole derivatives and a process for the preparation thereof
GB21427/66A Expired GB1099787A (en) 1965-05-19 1966-05-13 Novel nitro-imidazole derivatives and the manufacture thereof

Country Status (11)

Country Link
US (2) US3435049A (https=)
BE (1) BE681144A (https=)
BR (1) BR6679399D0 (https=)
CH (1) CH469716A (https=)
DE (1) DE1695139B2 (https=)
DK (1) DK114629B (https=)
FR (1) FR5448M (https=)
GB (3) GB1099789A (https=)
IL (1) IL25677A (https=)
NL (1) NL148889B (https=)
SE (1) SE337030B (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3700685A (en) * 1970-05-15 1972-10-24 Merck & Co Inc Nitroimidazole derivatives
US4218449A (en) * 1978-08-21 1980-08-19 John R. A. Simoons Treatment of rheumatoid arthritis and related diseases
JPS5692887A (en) * 1979-12-05 1981-07-27 Sumitomo Chem Co Ltd N-substituted imidazole derivative
FR2509302A1 (fr) * 1981-03-04 1983-01-14 Vyzk Ustav Zuslechtovaci Composes d'ammonium quaternaire, procede pour leur fabrication et utilisation de ces produits dans les apprets de finissage des tissus
DE3218130A1 (de) * 1982-05-14 1983-11-17 Basf Ag, 6700 Ludwigshafen Azolylmethyloxirane, verfahren zu ihrer herstellung und diese enthaltende fungizide
CH669494GA3 (https=) * 1984-11-05 1989-03-31
ZA858242B (en) * 1985-01-21 1986-08-27 Ciba Geigy Ag Cationic reaction products formed from 1-aminoalkyl-imidazole compounds and epihalohydrins
CH672219B5 (https=) * 1985-01-25 1990-05-15 Ciba Geigy Ag
FR2624736B1 (fr) * 1987-12-16 1991-03-22 Dietlin Francois Nouvelles compositions pharmaceutiques dispersibles dans l'eau a base d'ornidazole
DE3825586A1 (de) * 1988-07-28 1990-02-01 Basf Ag Substituierte imidazolylmethyloxirane und substituierte imidazolylpropene, ihre herstellung und sie enthaltende fungizide
FR2647448B1 (fr) * 1989-05-23 1991-08-23 Rhone Poulenc Sante Procede de preparation du (chloro-3 hydroxy-2 propyl)-1 methyl-2 nitro-5 imidazole
CA2494710C (en) * 2002-10-15 2011-05-03 Otsuka Pharmaceutical Co., Ltd. 1-substituted-4-nitroimidazole compound and method for preparing the same
CN100338039C (zh) * 2004-11-29 2007-09-19 南京圣和药业有限公司 奥硝唑光学对映体的制备及纯化方法
CN1314396C (zh) * 2005-04-28 2007-05-09 南京圣和药业有限公司 左旋奥硝唑在制备抗厌氧菌感染药物的应用
CN1332662C (zh) * 2005-04-29 2007-08-22 南京圣和药业有限公司 左旋奥硝唑的静脉给药制剂及其制备方法
CN1305469C (zh) * 2005-07-08 2007-03-21 南京圣和药业有限公司 左旋奥硝唑在制备抗寄生虫感染的药物中的应用
CN100368402C (zh) * 2005-11-16 2008-02-13 沈阳中海生物技术开发有限公司 奥硝唑光学对映体的制备方法
US9237750B2 (en) * 2012-07-04 2016-01-19 Ramot At Tel-Aviv University Ltd. Ornidazole and related compounds for use as herbicides
CN103073501B (zh) * 2012-12-07 2014-10-15 西安万隆制药股份有限公司 一种奥硝唑化合物
CN105585532B (zh) * 2014-10-24 2018-05-01 山东齐都药业有限公司 左奥硝唑反应液的后处理方法
CN105061323A (zh) * 2015-07-31 2015-11-18 珠海亿邦制药股份有限公司 一种奥硝唑化合物的精制方法
CN107235911A (zh) * 2016-03-28 2017-10-10 陕西合成药业股份有限公司 一种2-甲基-4-硝基咪唑衍生物及其制备方法和药用组合物的用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3275649A (en) * 1966-09-27 Process for the preparation of
US2061377A (en) * 1934-06-25 1936-11-17 Shell Dev Conversion of polyhalogenated alcohols
US2116439A (en) * 1936-04-21 1938-05-03 Du Pont Cyclic oxides and their preparation
DE1011618B (de) * 1954-12-06 1957-07-04 Bayer Ag Verfahren zur Herstellung basischer Diepoxydharze
US3043819A (en) * 1959-09-15 1962-07-10 Union Carbide Corp 2-(pyrazol)ethyl acrylates, process for their production, and polymerization products thereof
DE1445963A1 (de) * 1962-04-06 1969-12-04 Klosa Dipl Chem Dr Josef Verfahren zur Herstellung eines neuen Imidazolderivates
FR1379915A (fr) * 1963-12-17 1964-11-27 Rhone Poulenc Sa Procédé de préparation de dérivés de l'imidazole

Also Published As

Publication number Publication date
IL25677A (en) 1970-05-21
US3493582A (en) 1970-02-03
GB1099788A (en) 1968-01-17
US3435049A (en) 1969-03-25
DK114629B (da) 1969-07-21
BR6679399D0 (pt) 1973-10-23
BE681144A (https=) 1966-11-17
FR5448M (https=) 1967-10-09
DE1695139A1 (de) 1970-12-17
DE1695139B2 (de) 1976-11-04
GB1099787A (en) 1968-01-17
NL148889B (nl) 1976-03-15
SE337030B (https=) 1971-07-26
NL6606853A (https=) 1966-11-21
CH469716A (de) 1969-03-15

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