GB1096351A - Improvements in or relating to piperazine derivatives - Google Patents
Improvements in or relating to piperazine derivativesInfo
- Publication number
- GB1096351A GB1096351A GB7432/65A GB743265A GB1096351A GB 1096351 A GB1096351 A GB 1096351A GB 7432/65 A GB7432/65 A GB 7432/65A GB 743265 A GB743265 A GB 743265A GB 1096351 A GB1096351 A GB 1096351A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydrobromide
- alkyl
- prepared
- cycloalkyl
- relating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000004885 piperazines Chemical class 0.000 title 1
- 229940066771 systemic antihistamines piperazine derivative Drugs 0.000 title 1
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- -1 aminoethane halide Chemical class 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- BMYNFMYTOJXKLE-UHFFFAOYSA-N 3-azaniumyl-2-hydroxypropanoate Chemical compound NCC(O)C(O)=O BMYNFMYTOJXKLE-UHFFFAOYSA-N 0.000 abstract 1
- CPELXLSAUQHCOX-UHFFFAOYSA-N Hydrogen bromide Chemical compound Br CPELXLSAUQHCOX-UHFFFAOYSA-N 0.000 abstract 1
- 208000007101 Muscle Cramp Diseases 0.000 abstract 1
- 208000005392 Spasm Diseases 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/205—Radicals derived from carbonic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR942488A FR3288M (fr) | 1963-07-24 | 1963-07-24 | Anti-cholinergique. |
| FR942486 | 1963-07-24 | ||
| FR942490 | 1963-07-24 | ||
| FR942485A FR3108M (fr) | 1963-07-24 | 1963-07-24 | Nouveau dérivé anti-cholinergique. |
| FR942487A FR3287M (fr) | 1963-07-24 | 1963-07-24 | Anti-spasmodique. |
| FR957906A FR4051M (https=) | 1963-07-24 | 1963-12-20 | |
| CH5865 | 1965-01-04 | ||
| FR21389A FR150F (https=) | 1963-07-24 | 1965-06-18 | |
| CH1399165 | 1965-10-11 | ||
| CH1649065 | 1965-11-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1096351A true GB1096351A (en) | 1967-12-29 |
Family
ID=27579044
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB7432/65A Expired GB1096351A (en) | 1963-07-24 | 1965-02-20 | Improvements in or relating to piperazine derivatives |
| GB328/66A Expired GB1126002A (en) | 1963-07-24 | 1966-01-04 | New basic ethers and process for preparing same |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB328/66A Expired GB1126002A (en) | 1963-07-24 | 1966-01-04 | New basic ethers and process for preparing same |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US3331842A (https=) |
| BE (2) | BE664583A (https=) |
| FR (9) | FR150M (https=) |
| GB (2) | GB1096351A (https=) |
| NL (1) | NL6600012A (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3718643A (en) * | 1970-09-30 | 1973-02-27 | Squibb & Sons Inc | Derivatives of bis(-hydroxyaryl)alkanoic acids |
| US5234946A (en) * | 1987-11-27 | 1993-08-10 | Banyu Pharmaceutical Co., Ltd. | Substituted alkylamine derivatives |
| US4977156A (en) * | 1988-07-26 | 1990-12-11 | The Dow Chemical Company | Amino piperazine esters showing biocidal activity |
| AU2001286965A1 (en) | 2000-08-31 | 2002-03-13 | Advanced Medicine, Inc. | Sodium channel modulators |
| WO2002057215A2 (en) | 2001-01-16 | 2002-07-25 | Theravance, Inc. | Sodium channel modulators |
| AU2016250527B2 (en) | 2015-04-24 | 2021-01-14 | Bruin Biometrics, Llc | Apparatus and methods for determining damaged tissue using sub-epidermal moisture measurements |
| WO2019194620A1 (ko) | 2018-04-06 | 2019-10-10 | 주식회사 엘지화학 | 열가소성 수지 조성물 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2880209A (en) * | 1954-09-02 | 1959-03-31 | Harfenist Morton | Piperazine quaternary salts having parasitical activity and method of making |
| US2794804A (en) * | 1955-03-24 | 1957-06-04 | American Cyanamid Co | Substituted piperazines and method of preparing the same |
| US3015657A (en) * | 1959-05-28 | 1962-01-02 | Charles F Geschickter | 1-carbalkoxy-4-(aminoalkanol) piperazines |
| US3247199A (en) * | 1961-01-27 | 1966-04-19 | Ciba Geigy Corp | Diphenyl-methanes |
| US3274054A (en) * | 1963-06-28 | 1966-09-20 | American Cyanamid Co | Antiviral compositions and method of administration |
-
1960
- 1960-08-08 FR FR835281A patent/FR150M/fr not_active Expired
-
1963
- 1963-07-24 FR FR942485A patent/FR3108M/fr not_active Expired
- 1963-07-24 FR FR942488A patent/FR3288M/fr not_active Expired
- 1963-07-24 FR FR942487A patent/FR3287M/fr not_active Expired
- 1963-12-20 FR FR957906A patent/FR4051M/fr not_active Expired
-
1964
- 1964-07-07 US US380943A patent/US3331842A/en not_active Expired - Lifetime
-
1965
- 1965-02-20 GB GB7432/65A patent/GB1096351A/en not_active Expired
- 1965-05-28 BE BE664583D patent/BE664583A/xx unknown
- 1965-06-18 FR FR21389A patent/FR150F/fr not_active Expired
- 1965-12-16 US US514361A patent/US3455918A/en not_active Expired - Lifetime
- 1965-12-28 FR FR43973A patent/FR1481952A/fr not_active Expired
-
1966
- 1966-01-03 BE BE674688D patent/BE674688A/xx unknown
- 1966-01-03 NL NL6600012A patent/NL6600012A/xx unknown
- 1966-01-04 GB GB328/66A patent/GB1126002A/en not_active Expired
- 1966-03-10 FR FR52845A patent/FR5289M/fr not_active Expired
- 1966-03-10 FR FR52846A patent/FR5290M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR5290M (https=) | 1967-08-07 |
| FR4051M (https=) | 1966-05-06 |
| FR5289M (https=) | 1967-08-07 |
| US3455918A (en) | 1969-07-15 |
| FR3287M (fr) | 1965-06-04 |
| FR150M (fr) | 1961-01-20 |
| GB1126002A (en) | 1968-09-05 |
| FR150F (https=) | 1967-03-13 |
| US3331842A (en) | 1967-07-18 |
| FR1481952A (fr) | 1967-05-26 |
| NL6600012A (https=) | 1966-07-05 |
| FR3288M (fr) | 1965-06-04 |
| FR3108M (fr) | 1965-03-12 |
| BE664583A (https=) | 1983-09-16 |
| BE674688A (https=) | 1966-07-04 |
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