GB1095569A - A method and an apparatus for carrying out simultaneously a plurality of chromatographic separations in columns - Google Patents

A method and an apparatus for carrying out simultaneously a plurality of chromatographic separations in columns

Info

Publication number
GB1095569A
GB1095569A GB1829565A GB1829565A GB1095569A GB 1095569 A GB1095569 A GB 1095569A GB 1829565 A GB1829565 A GB 1829565A GB 1829565 A GB1829565 A GB 1829565A GB 1095569 A GB1095569 A GB 1095569A
Authority
GB
United Kingdom
Prior art keywords
distributor
columns
streams
eluate
eluent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1829565A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Czech Academy of Sciences CAS
Original Assignee
Czech Academy of Sciences CAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Czech Academy of Sciences CAS filed Critical Czech Academy of Sciences CAS
Publication of GB1095569A publication Critical patent/GB1095569A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/466—Flow patterns using more than one column with separation columns in parallel
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/84—Preparation of the fraction to be distributed

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

1,095,569. Chromatography elution and analysis system. CESKOSLOVENSKA AKAD. EMIE VED. April 30, 1965 [May 4, 1964], No. 18295/65. Heading B1X. A plurality of chromatographic separations are carried out simultaneously by supplying eluent to a pump which passes the eluent to a distributor which feeds a plurality of columns cyclically. As illustrated in the Figure, eluent is passed by pump Pv to distributor Kv and thus in sequence via dosers D 1 -D4 to columns V 1 -V4. A further pump PN and distributor KN feed a reagent (e.g. ninhydrin reagent for amino-acid separations) to the eluate streams in sequence, the two distributors preferably being in phase. Three-way cocks d 1 -d4, provide for switching the eluate to drain. The tubes from the columns are of capillary dimensions and pass the eluate-reagent stream to capillary reactors KR 1 - KR4 in a common constant temperature bath. The streams then pass to photometric cells F 1 - F4 having measuring elements E 1 - E4 connected to a common recorder Z. Finally the streams are led to a distributor KF which can conduct any stream to a flow meter B while the remaining streams are discharged to drain. Each measuring cell outlet may be fitted with a flow meter. A known solution may be used in one column, and the recorder may be responsive to a light intensity ratio.
GB1829565A 1964-05-04 1965-04-30 A method and an apparatus for carrying out simultaneously a plurality of chromatographic separations in columns Expired GB1095569A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS259064 1964-05-04

Publications (1)

Publication Number Publication Date
GB1095569A true GB1095569A (en) 1967-12-20

Family

ID=5363458

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1829565A Expired GB1095569A (en) 1964-05-04 1965-04-30 A method and an apparatus for carrying out simultaneously a plurality of chromatographic separations in columns

Country Status (3)

Country Link
CH (1) CH475017A (en)
GB (1) GB1095569A (en)
SE (1) SE321103B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998035227A1 (en) * 1997-02-06 1998-08-13 Solvay Pharmaceuticals Gmbh Method and device for parallel chromatography
EP1850129A1 (en) * 2006-12-08 2007-10-31 Agilent Technologies, Inc. Fluid separation system with multiple flow channels

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998035227A1 (en) * 1997-02-06 1998-08-13 Solvay Pharmaceuticals Gmbh Method and device for parallel chromatography
US6197198B1 (en) * 1997-02-06 2001-03-06 Solvay Pharmaceuticals Gmbh Method and device for parallel chromatography
EP1850129A1 (en) * 2006-12-08 2007-10-31 Agilent Technologies, Inc. Fluid separation system with multiple flow channels

Also Published As

Publication number Publication date
CH475017A (en) 1969-07-15
DE1598214B2 (en) 1973-02-15
SE321103B (en) 1970-02-23
DE1598214A1 (en) 1969-12-11

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