GB1089483A - Improvements in or relating to 4h-benzo(4,5)cyclohepta (1,2-b) thiophene derivatives - Google Patents
Improvements in or relating to 4h-benzo(4,5)cyclohepta (1,2-b) thiophene derivativesInfo
- Publication number
- GB1089483A GB1089483A GB3355/65A GB335565A GB1089483A GB 1089483 A GB1089483 A GB 1089483A GB 3355/65 A GB3355/65 A GB 3355/65A GB 335565 A GB335565 A GB 335565A GB 1089483 A GB1089483 A GB 1089483A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- cyclohepta
- benzo
- acid
- thiophen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- MHGBFEJHQLAUQM-UHFFFAOYSA-N 10h-benzo[1,2]cyclohepta[3,4-b]thiophene Chemical class C1=CC2=CC=CC=C2CC2=C1SC=C2 MHGBFEJHQLAUQM-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 239000002253 acid Substances 0.000 abstract 2
- -1 chloroformic acid ester Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- BYSDXOIAAYZTBJ-UHFFFAOYSA-N 2-(2-thiophen-2-ylethyl)benzoic acid Chemical compound OC(=O)C1=CC=CC=C1CCC1=CC=CS1 BYSDXOIAAYZTBJ-UHFFFAOYSA-N 0.000 abstract 1
- ISSJZCAENPGUEW-BQYQJAHWSA-N 2-[(e)-2-thiophen-2-ylethenyl]benzoic acid Chemical compound OC(=O)C1=CC=CC=C1\C=C\C1=CC=CS1 ISSJZCAENPGUEW-BQYQJAHWSA-N 0.000 abstract 1
- JAGBUENUSNSSFW-UHFFFAOYSA-N 4,5-dihydrobenzo[1,2]cyclohepta[3,4-b]thiophen-10-one Chemical compound C1CC2=CC=CC=C2C(=O)C2=C1SC=C2 JAGBUENUSNSSFW-UHFFFAOYSA-N 0.000 abstract 1
- XBSHFWJFRSEMTE-UHFFFAOYSA-N 6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,8,10,12-hexaen-2-ol Chemical class S1C2=C(C=C1)C(C1=C(C=C2)C=CC=C1)O XBSHFWJFRSEMTE-UHFFFAOYSA-N 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- AZLFZBHRVLSJRH-UHFFFAOYSA-N N,N-dimethyl-3-(6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,8,10,12-hexaen-2-ylidene)propan-1-amine Chemical compound CN(CCC=C1C2=C(C=CC=3SC=CC31)C=CC=C2)C AZLFZBHRVLSJRH-UHFFFAOYSA-N 0.000 abstract 1
- 206010029333 Neurosis Diseases 0.000 abstract 1
- 208000012545 Psychophysiologic disease Diseases 0.000 abstract 1
- 208000028017 Psychotic disease Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- AKYJPOPHGMQXHH-UHFFFAOYSA-N benzo[1,2]cyclohepta[3,4-b]thiophen-10-one Chemical compound C1=CC2=CC=CC=C2C(=O)C2=C1SC=C2 AKYJPOPHGMQXHH-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 238000003402 intramolecular cyclocondensation reaction Methods 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 208000015238 neurotic disease Diseases 0.000 abstract 1
- JKNKNWJNCOJPLI-UHFFFAOYSA-N o-phthalaldehydic acid Chemical compound C1=CC=C2C(O)OC(=O)C2=C1 JKNKNWJNCOJPLI-UHFFFAOYSA-N 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 150000003673 urethanes Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
- C07D333/80—Seven-membered rings
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F2/00—Processes of polymerisation
- C08F2/38—Polymerisation using regulators, e.g. chain terminating agents, e.g. telomerisation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH127564A CH440321A (de) | 1964-02-04 | 1964-02-04 | Verfahren zur Herstellung von neuen heterocyclischen Verbindungen |
| CH1324664 | 1964-10-13 | ||
| CH806165A CH473138A (de) | 1964-02-04 | 1965-06-09 | Verfahren zur Herstellung von neuen 9,10-Dihydro-4H-benzo(4,5)cyclohepta(1,2-b)tiophen-Derivaten |
| CH1519165A CH473146A (de) | 1964-02-04 | 1965-11-03 | Verfahren zur Herstellung von neuen 4H-Benzo(4,5)cyclohepta(1,2-b)thiophen-Derivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1089483A true GB1089483A (en) | 1967-11-01 |
Family
ID=27428140
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3355/65A Expired GB1089483A (en) | 1964-02-04 | 1965-01-26 | Improvements in or relating to 4h-benzo(4,5)cyclohepta (1,2-b) thiophene derivatives |
| GB47266/66A Expired GB1159480A (en) | 1964-02-04 | 1966-10-21 | 4H-Benzo[4,5]Cyclohepta[1,2-b]-Thiophene Derivatives |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB47266/66A Expired GB1159480A (en) | 1964-02-04 | 1966-10-21 | 4H-Benzo[4,5]Cyclohepta[1,2-b]-Thiophene Derivatives |
Country Status (12)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU195800B (en) * | 1983-10-13 | 1988-07-28 | Sandoz Ltd | Process for producing 4h-benzo/4,5/cylopenta/1,2-b/ thiofene derivatives and pharmaceutical compositions containing them |
| ATE516804T1 (de) | 1999-09-13 | 2011-08-15 | Bridge Pharma Inc | Optisch aktive isomere von ketotifen und deren therapeutisch wirksame metabolite |
-
1965
- 1965-01-26 GB GB3355/65A patent/GB1089483A/en not_active Expired
- 1965-01-28 OA OA51413A patent/OA01524A/xx unknown
- 1965-01-29 NL NL6501154A patent/NL125442C/xx active
- 1965-02-01 DE DES95277A patent/DE1238040B/de active Pending
- 1965-02-02 FR FR4164A patent/FR1441486A/fr not_active Expired
- 1965-02-02 BE BE659178A patent/BE659178A/xx unknown
- 1965-02-02 FI FI0244/65A patent/FI42216B/fi active
- 1965-02-03 SE SE1405/65A patent/SE306323B/xx unknown
- 1965-02-03 IL IL22905A patent/IL22905A/en unknown
- 1965-02-04 BR BR166936/65A patent/BR6566936D0/pt unknown
- 1965-04-30 FR FR15304A patent/FR4369M/fr not_active Expired
- 1965-06-09 CH CH806165A patent/CH473138A/de unknown
- 1965-08-09 BE BE668052A patent/BE668052A/xx unknown
- 1965-08-09 NL NL6510326A patent/NL6510326A/xx unknown
- 1965-08-10 FR FR27925A patent/FR91208E/fr not_active Expired
- 1965-11-03 CH CH1519165A patent/CH473146A/de unknown
-
1966
- 1966-10-21 GB GB47266/66A patent/GB1159480A/en not_active Expired
- 1966-10-28 DE DE19661620420 patent/DE1620420A1/de active Pending
- 1966-10-31 BR BR184229/66A patent/BR6684229D0/pt unknown
- 1966-11-02 ES ES332985A patent/ES332985A2/es not_active Expired
- 1966-11-02 FR FR82202A patent/FR92121E/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BR6684229D0 (pt) | 1973-12-26 |
| BE668052A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1966-02-09 |
| ES332985A2 (es) | 1968-03-16 |
| DE1238040B (de) | 1967-04-06 |
| CH473146A (de) | 1969-05-31 |
| CH473138A (de) | 1969-05-31 |
| FR92121E (fr) | 1968-09-27 |
| FR4369M (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1966-08-22 |
| OA01524A (fr) | 1969-07-21 |
| BR6566936D0 (pt) | 1973-08-14 |
| SE306323B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1968-11-25 |
| FR1441486A (fr) | 1966-06-10 |
| BE659178A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1965-08-02 |
| NL6510326A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1966-12-12 |
| DE1620420A1 (de) | 1970-03-12 |
| IL22905A (en) | 1969-01-29 |
| GB1159480A (en) | 1969-07-23 |
| FI42216B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1970-03-02 |
| FR91208E (fr) | 1968-05-03 |
| NL6501154A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1965-08-05 |
| NL125442C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1968-06-17 |
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