GB1085655A - Process for the preparation of 16-alkyl-pregnadiene compounds - Google Patents

Process for the preparation of 16-alkyl-pregnadiene compounds

Info

Publication number
GB1085655A
GB1085655A GB2479663A GB2479663A GB1085655A GB 1085655 A GB1085655 A GB 1085655A GB 2479663 A GB2479663 A GB 2479663A GB 2479663 A GB2479663 A GB 2479663A GB 1085655 A GB1085655 A GB 1085655A
Authority
GB
United Kingdom
Prior art keywords
alkyl
preparation
compounds
oxidation
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2479663A
Inventor
Colin Leslie Hewett
Gilbert Frederick Woods
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon Laboratories Ltd
Original Assignee
Organon Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon Laboratories Ltd filed Critical Organon Laboratories Ltd
Priority to GB2479663A priority Critical patent/GB1085655A/en
Priority to GB3919763A priority patent/GB1100534A/en
Priority to NL6406595A priority patent/NL6406595A/xx
Priority to SE745864A priority patent/SE316767B/xx
Priority to DK306164A priority patent/DK113919B/en
Priority to FR979032A priority patent/FR1411727A/en
Priority to BR16017464A priority patent/BR6460174D0/en
Priority to DE19641468444 priority patent/DE1468444A1/en
Priority to BE649503D priority patent/BE649503A/xx
Publication of GB1085655A publication Critical patent/GB1085655A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
    • C08L67/06—Unsaturated polyesters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Steroid Compounds (AREA)

Abstract

Novel 16a (C1- 4 alkyl) - 3,20 - diketo - D 4,6-pregnadienes are prepared by oxidation of the corresponding D 4-compounds with a quinone having an oxidation-reduction potential of less than - 0.5 v. The novel steroids are stated to have progestative, pregnancy-maintaining and gonadinhibiting properties, and they may be made up into pharmaceutical compositions for oral or parenteral administration with suitable carriers.
GB2479663A 1963-06-21 1963-06-21 Process for the preparation of 16-alkyl-pregnadiene compounds Expired GB1085655A (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
GB2479663A GB1085655A (en) 1963-06-21 1963-06-21 Process for the preparation of 16-alkyl-pregnadiene compounds
GB3919763A GB1100534A (en) 1963-06-21 1963-10-04 16-alkyl-pregnanes
NL6406595A NL6406595A (en) 1963-06-21 1964-06-11
SE745864A SE316767B (en) 1963-06-21 1964-06-17
DK306164A DK113919B (en) 1963-06-21 1964-06-18 Analogous process for the preparation of 16α-alkyl-Δ <4,6> -pregnadiene-3,20-diones.
FR979032A FR1411727A (en) 1963-06-21 1964-06-19 Process for the preparation of 16-alkyl-progesterone derivatives
BR16017464A BR6460174D0 (en) 1963-06-21 1964-06-19 PROCESS FOR THE PREPARATION OF NEW 16-ALPHA-ALKYL-PROGESTERONE DERIVATIVES
DE19641468444 DE1468444A1 (en) 1963-06-21 1964-06-19 Process for the preparation of 16 alpha-alkyl progesterone derivatives
BE649503D BE649503A (en) 1963-06-21 1964-06-19

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2479663A GB1085655A (en) 1963-06-21 1963-06-21 Process for the preparation of 16-alkyl-pregnadiene compounds
GB3919763A GB1100534A (en) 1963-06-21 1963-10-04 16-alkyl-pregnanes

Publications (1)

Publication Number Publication Date
GB1085655A true GB1085655A (en) 1967-10-04

Family

ID=26257297

Family Applications (2)

Application Number Title Priority Date Filing Date
GB2479663A Expired GB1085655A (en) 1963-06-21 1963-06-21 Process for the preparation of 16-alkyl-pregnadiene compounds
GB3919763A Expired GB1100534A (en) 1963-06-21 1963-10-04 16-alkyl-pregnanes

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB3919763A Expired GB1100534A (en) 1963-06-21 1963-10-04 16-alkyl-pregnanes

Country Status (7)

Country Link
BE (1) BE649503A (en)
BR (1) BR6460174D0 (en)
DE (1) DE1468444A1 (en)
DK (1) DK113919B (en)
GB (2) GB1085655A (en)
NL (1) NL6406595A (en)
SE (1) SE316767B (en)

Also Published As

Publication number Publication date
SE316767B (en) 1969-11-03
GB1100534A (en) 1968-01-24
DE1468444A1 (en) 1969-01-09
DK113919B (en) 1969-05-12
NL6406595A (en) 1964-12-22
BE649503A (en) 1964-12-21
BR6460174D0 (en) 1973-12-26

Similar Documents

Publication Publication Date Title
CA970683A (en) Compositions of matter comprising solution of crude 1,2-benzisothiazolone
GB1104462A (en) 7ª‡-methyl-steroids of the oestrane series
GB1211219A (en) 21-aldehydes of the pregnane series and derivatives thereof and process for their manufacture
CA966424A (en) Anti-seborrheic compositions containing 2-trans-4-trans-pentadienoic
GB1085655A (en) Process for the preparation of 16-alkyl-pregnadiene compounds
IL45203A0 (en) Cyclic sulphoxides and sulphones,processes for their preparation and compositions containing them
GB1141214A (en) New derivatives of proscillaridin a
AU472706B2 (en) Anaesthetic steroid compositions
GB1027891A (en) Esters of dianhydro-hexitols
ES386465A1 (en) Neriifolin derivatives
IL36127A0 (en) Novel esters of the pregnane series,their preparation and pharmaceutical compositions containing them
IL36323A (en) 16-methylene-9 beta,10 alpha-steroids of the pregnane series,their production and pharmaceutical compositions containing them
GB1113813A (en) 13-alkyl steroid esters
CA661334A (en) Compositions for lowering blood cholesterol
IL35512A0 (en) 14beta,18-(epoxyethanoimino)steroids,their production and pharmaceutical compositions containing them
AU285651B2 (en) 2, 2&#39; bipyridine pharmaceutical compositions
GB1183802A (en) Orally Effective Oestrogens
AU248634B2 (en) phenothiazine compounds, their PRODUCTION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
AU5164664A (en) 2, 2&#39; bipyridine pharmaceutical compositions
AU500961A (en) phenothiazine compounds, their PRODUCTION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
ES375060A1 (en) 21-esters of triamcinolone and triamcinolone acetonide and a method of preparing them
AU473308B2 (en) Steroid anaesthetic compositions
GB1043157A (en) 10-hydroxy-19-norpregnanes
IL36609A0 (en) Halogenosteroids of the pregnane series,their manufacture and pharmaceutical compositions containing them
AU2494362A (en) Compositions having nematocidal properties