ES375060A1 - 21-esters of triamcinolone and triamcinolone acetonide and a method of preparing them - Google Patents
21-esters of triamcinolone and triamcinolone acetonide and a method of preparing themInfo
- Publication number
- ES375060A1 ES375060A1 ES375060A ES375060A ES375060A1 ES 375060 A1 ES375060 A1 ES 375060A1 ES 375060 A ES375060 A ES 375060A ES 375060 A ES375060 A ES 375060A ES 375060 A1 ES375060 A1 ES 375060A1
- Authority
- ES
- Spain
- Prior art keywords
- triamcinolone
- esters
- preparing
- acetonide
- trimethoxybenzoates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
Abstract
Triamcinolone and its 16,17-acetonide are esterified to form the novel 21-pantothenates, 21 - (2,5 - dihydroxybenzoates), 21 - (2,4,6 - trimethoxybenzoates) and 21-(3,4,5-trimethoxybenzoates) thereof. The said 21-esters are stated to possess antiinflammatory activity and may be made up with carriers into pharmaceutical compositions for oral, rectal and topical administration.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR183120 | 1968-12-31 | ||
FR69183309A FR8289M (en) | 1968-12-31 | 1969-03-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES375060A1 true ES375060A1 (en) | 1972-03-16 |
Family
ID=26182462
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES375060A Expired ES375060A1 (en) | 1968-12-31 | 1969-12-30 | 21-esters of triamcinolone and triamcinolone acetonide and a method of preparing them |
Country Status (5)
Country | Link |
---|---|
BE (1) | BE743689A (en) |
DE (1) | DE1965217A1 (en) |
ES (1) | ES375060A1 (en) |
FR (1) | FR8289M (en) |
GB (1) | GB1248500A (en) |
-
1969
- 1969-03-31 FR FR69183309A patent/FR8289M/fr not_active Expired
- 1969-12-24 BE BE743689D patent/BE743689A/xx not_active IP Right Cessation
- 1969-12-29 DE DE19691965217 patent/DE1965217A1/en active Pending
- 1969-12-30 ES ES375060A patent/ES375060A1/en not_active Expired
- 1969-12-31 GB GB6356869A patent/GB1248500A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DE1965217A1 (en) | 1970-08-20 |
FR8289M (en) | 1970-11-09 |
BE743689A (en) | 1970-06-24 |
GB1248500A (en) | 1971-10-06 |
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