GB1084150A - - Google Patents
Info
- Publication number
- GB1084150A GB1084150A GB1084150DA GB1084150A GB 1084150 A GB1084150 A GB 1084150A GB 1084150D A GB1084150D A GB 1084150DA GB 1084150 A GB1084150 A GB 1084150A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- reacting
- reactive
- amines
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000001412 amines Chemical class 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000004185 ester group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 125000000467 secondary amino group Chemical group [H]N([*:1])[*:2] 0.000 abstract 2
- WOXFMYVTSLAQMO-UHFFFAOYSA-N 2-Pyridinemethanamine Chemical compound NCC1=CC=CC=N1 WOXFMYVTSLAQMO-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000001882 diuretic effect Effects 0.000 abstract 1
- 239000008298 dragée Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical class O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 abstract 1
- 229960000278 theophylline Drugs 0.000 abstract 1
- 230000000304 vasodilatating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH41465A CH458365A (de) | 1965-01-12 | 1965-01-12 | Verfahren zur Herstellung von neuen Picolylamin-Derivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1084150A true GB1084150A (en, 2012) |
Family
ID=4186481
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1084150D Active GB1084150A (en, 2012) | 1965-01-12 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US3350400A (en, 2012) |
| BE (1) | BE674919A (en, 2012) |
| BR (1) | BR6676358D0 (en, 2012) |
| CH (1) | CH458365A (en, 2012) |
| DE (1) | DE1545772B1 (en, 2012) |
| DK (1) | DK114482B (en, 2012) |
| ES (1) | ES321531A1 (en, 2012) |
| FR (2) | FR1463438A (en, 2012) |
| GB (1) | GB1084150A (en, 2012) |
| IT (1) | IT7830644A0 (en, 2012) |
| NL (2) | NL6600250A (en, 2012) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4406903A (en) * | 1981-01-21 | 1983-09-27 | John Wyeth And Brother Limited | Xanthine derivatives useful as antidepressives |
| DE60336485D1 (de) | 2002-08-19 | 2011-05-05 | Pfizer | Kombinationstherapie gegen hyperproliferative erkrankungen |
| US20060063803A1 (en) * | 2004-09-23 | 2006-03-23 | Pfizer Inc | 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds |
| US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
| US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| WO2008070496A2 (en) | 2006-12-01 | 2008-06-12 | Bristol-Myers Squibb Company | N- ( (3-benzyl) -2, 2- (bis-phenyl) -propan-1-amine derivatives as cetp inhibitors for the treatment of atherosclerosis and cardiovascular diseases |
| AU2014255381A1 (en) | 2013-04-17 | 2015-10-08 | Pfizer Inc. | N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases |
| WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
| CN113574055B (zh) | 2019-01-18 | 2024-07-23 | 阿斯利康(瑞典)有限公司 | Pcsk9抑制剂及其使用方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3032554A (en) * | 1962-05-01 | Process for the preparation of new | ||
| US3029239A (en) * | 1954-04-17 | 1962-04-10 | Chemiewerk Homburg Zweignieder | Basic substituted 1-and 7-alkylxanthines or salts thereof |
| DE1011424B (de) * | 1954-04-17 | 1957-07-04 | Chemiewerk Homburg Ag | Verfahren zur Herstellung von basisch substituierten 7-Alkyl-xanthinderivaten oder deren Salzen |
| DE1018869B (de) * | 1954-12-14 | 1957-11-07 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung von Aminoalkylpurinderivaten |
| DE1112983B (de) * | 1958-11-21 | 1961-08-24 | Sandoz Ag | Verfahren zur Herstellung von Theophyllin-Derivaten |
| CH402872A (de) * | 1959-12-18 | 1965-11-30 | Nippon Shinyaku Co Ltd | Verfahren zur Herstellung von Theophyllin- oder Theobromin-Derivaten |
-
0
- GB GB1084150D patent/GB1084150A/en active Active
- NL NL128191D patent/NL128191C/xx active
-
1965
- 1965-01-12 CH CH41465A patent/CH458365A/de unknown
- 1965-01-21 FR FR45538A patent/FR1463438A/fr not_active Expired
- 1965-10-14 DE DE19651545772 patent/DE1545772B1/de not_active Withdrawn
- 1965-10-20 US US499047A patent/US3350400A/en not_active Expired - Lifetime
-
1966
- 1966-01-07 ES ES0321531A patent/ES321531A1/es not_active Expired
- 1966-01-10 BE BE674919D patent/BE674919A/xx unknown
- 1966-01-10 NL NL6600250A patent/NL6600250A/xx unknown
- 1966-01-11 DK DK12166AA patent/DK114482B/da unknown
- 1966-01-11 BR BR176358/66A patent/BR6676358D0/pt unknown
- 1966-01-11 FR FR45417A patent/FR5128M/fr not_active Expired
-
1978
- 1978-12-06 IT IT7830644A patent/IT7830644A0/it unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK114482B (da) | 1969-07-07 |
| IT7830644A0 (it) | 1978-12-06 |
| BE674919A (en, 2012) | 1966-07-11 |
| US3350400A (en) | 1967-10-31 |
| FR5128M (en, 2012) | 1967-06-05 |
| CH458365A (de) | 1968-08-30 |
| NL128191C (en, 2012) | |
| NL6600250A (en, 2012) | 1966-07-13 |
| FR1463438A (fr) | 1966-12-23 |
| DE1545772B1 (de) | 1969-12-11 |
| BR6676358D0 (pt) | 1973-09-06 |
| ES321531A1 (es) | 1966-11-01 |
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