GB1073172A - Improvements relating to test packs for the detection of uric acid - Google Patents
Improvements relating to test packs for the detection of uric acidInfo
- Publication number
- GB1073172A GB1073172A GB25127/64A GB2512764A GB1073172A GB 1073172 A GB1073172 A GB 1073172A GB 25127/64 A GB25127/64 A GB 25127/64A GB 2512764 A GB2512764 A GB 2512764A GB 1073172 A GB1073172 A GB 1073172A
- Authority
- GB
- United Kingdom
- Prior art keywords
- blood
- phenylenediamine
- cyanide
- hydroxymethyl
- tris
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 title abstract 2
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 title abstract 2
- 229940116269 uric acid Drugs 0.000 title abstract 2
- 238000001514 detection method Methods 0.000 title 1
- 210000004369 blood Anatomy 0.000 abstract 4
- 239000008280 blood Substances 0.000 abstract 4
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 3
- 108010092464 Urate Oxidase Proteins 0.000 abstract 3
- -1 alkali metal azide Chemical class 0.000 abstract 3
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 2
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 239000000872 buffer Substances 0.000 abstract 2
- YCIMNLLNPGFGHC-UHFFFAOYSA-N catechol Chemical compound OC1=CC=CC=C1O YCIMNLLNPGFGHC-UHFFFAOYSA-N 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 2
- 229940088598 enzyme Drugs 0.000 abstract 2
- LHGVFZTZFXWLCP-UHFFFAOYSA-N guaiacol Chemical compound COC1=CC=CC=C1O LHGVFZTZFXWLCP-UHFFFAOYSA-N 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- 230000003617 peroxidasic effect Effects 0.000 abstract 2
- WQGWDDDVZFFDIG-UHFFFAOYSA-N pyrogallol Chemical compound OC1=CC=CC(O)=C1O WQGWDDDVZFFDIG-UHFFFAOYSA-N 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- 229940005267 urate oxidase Drugs 0.000 abstract 2
- GEYOCULIXLDCMW-UHFFFAOYSA-N 1,2-phenylenediamine Chemical compound NC1=CC=CC=C1N GEYOCULIXLDCMW-UHFFFAOYSA-N 0.000 abstract 1
- CZWZDUAKSLOMPP-DFWYDOINSA-N 2-amino-2-(hydroxymethyl)propane-1,3-diol;(2s)-2-aminopentanedioic acid Chemical compound OCC(N)(CO)CO.OC(=O)[C@@H](N)CCC(O)=O CZWZDUAKSLOMPP-DFWYDOINSA-N 0.000 abstract 1
- UHGULLIUJBCTEF-UHFFFAOYSA-N 2-aminobenzothiazole Chemical compound C1=CC=C2SC(N)=NC2=C1 UHGULLIUJBCTEF-UHFFFAOYSA-N 0.000 abstract 1
- JRBJSXQPQWSCCF-UHFFFAOYSA-N 3,3'-Dimethoxybenzidine Chemical compound C1=C(N)C(OC)=CC(C=2C=C(OC)C(N)=CC=2)=C1 JRBJSXQPQWSCCF-UHFFFAOYSA-N 0.000 abstract 1
- NUIURNJTPRWVAP-UHFFFAOYSA-N 3,3'-Dimethylbenzidine Chemical compound C1=C(N)C(C)=CC(C=2C=C(C)C(N)=CC=2)=C1 NUIURNJTPRWVAP-UHFFFAOYSA-N 0.000 abstract 1
- ROFVEXUMMXZLPA-UHFFFAOYSA-N Bipyridyl Chemical group N1=CC=CC=C1C1=CC=CC=N1 ROFVEXUMMXZLPA-UHFFFAOYSA-N 0.000 abstract 1
- BTBUEUYNUDRHOZ-UHFFFAOYSA-N Borate Chemical compound [O-]B([O-])[O-] BTBUEUYNUDRHOZ-UHFFFAOYSA-N 0.000 abstract 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 abstract 1
- XFXPMWWXUTWYJX-UHFFFAOYSA-N Cyanide Chemical compound N#[C-] XFXPMWWXUTWYJX-UHFFFAOYSA-N 0.000 abstract 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 abstract 1
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 abstract 1
- 239000004471 Glycine Substances 0.000 abstract 1
- 241000147041 Guaiacum officinale Species 0.000 abstract 1
- OFOBLEOULBTSOW-UHFFFAOYSA-L Malonate Chemical compound [O-]C(=O)CC([O-])=O OFOBLEOULBTSOW-UHFFFAOYSA-L 0.000 abstract 1
- 102000003992 Peroxidases Human genes 0.000 abstract 1
- 229920002253 Tannate Polymers 0.000 abstract 1
- 230000003213 activating effect Effects 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 230000002789 catalaselike Effects 0.000 abstract 1
- 239000002738 chelating agent Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- OIDPCXKPHYRNKH-UHFFFAOYSA-J chrome alum Chemical compound [K]OS(=O)(=O)O[Cr]1OS(=O)(=O)O1 OIDPCXKPHYRNKH-UHFFFAOYSA-J 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229960001484 edetic acid Drugs 0.000 abstract 1
- 210000003743 erythrocyte Anatomy 0.000 abstract 1
- 229940091561 guaiac Drugs 0.000 abstract 1
- 229960001867 guaiacol Drugs 0.000 abstract 1
- 229910001385 heavy metal Inorganic materials 0.000 abstract 1
- BTIJJDXEELBZFS-UHFFFAOYSA-K hemin Chemical compound [Cl-].[Fe+3].[N-]1C(C=C2C(=C(C)C(C=C3C(=C(C)C(=C4)[N-]3)C=C)=N2)C=C)=C(C)C(CCC(O)=O)=C1C=C1C(CCC(O)=O)=C(C)C4=N1 BTIJJDXEELBZFS-UHFFFAOYSA-K 0.000 abstract 1
- 150000002500 ions Chemical class 0.000 abstract 1
- 229910052742 iron Inorganic materials 0.000 abstract 1
- YWBREQLMDUVNIR-UHFFFAOYSA-N iron(2+);hexacyanide Chemical compound [Fe+2].[Fe+2].[Fe+2].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-] YWBREQLMDUVNIR-UHFFFAOYSA-N 0.000 abstract 1
- 150000002672 m-cresols Chemical class 0.000 abstract 1
- MEFBJEMVZONFCJ-UHFFFAOYSA-N molybdate Chemical class [O-][Mo]([O-])(=O)=O MEFBJEMVZONFCJ-UHFFFAOYSA-N 0.000 abstract 1
- 229960003512 nicotinic acid Drugs 0.000 abstract 1
- 235000001968 nicotinic acid Nutrition 0.000 abstract 1
- 239000011664 nicotinic acid Substances 0.000 abstract 1
- 150000002883 o-cresols Chemical class 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- BHAAPTBBJKJZER-UHFFFAOYSA-N p-anisidine Chemical class COC1=CC=C(N)C=C1 BHAAPTBBJKJZER-UHFFFAOYSA-N 0.000 abstract 1
- 108040007629 peroxidase activity proteins Proteins 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 229940079877 pyrogallol Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 abstract 1
- UJMBCXLDXJUMFB-GLCFPVLVSA-K tartrazine Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)C1=NN(C=2C=CC(=CC=2)S([O-])(=O)=O)C(=O)C1\N=N\C1=CC=C(S([O-])(=O)=O)C=C1 UJMBCXLDXJUMFB-GLCFPVLVSA-K 0.000 abstract 1
- 229960000943 tartrazine Drugs 0.000 abstract 1
- 235000012756 tartrazine Nutrition 0.000 abstract 1
- 239000004149 tartrazine Substances 0.000 abstract 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/62—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving uric acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2326/00—Chromogens for determinations of oxidoreductase enzymes
- C12Q2326/10—Benzidines
- C12Q2326/14—Ortho-Tolidine, i.e. 3,3'-dimethyl-(1,1'-biphenyl-4,4'-diamine)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US288498A US3349006A (en) | 1963-06-17 | 1963-06-17 | Process and composition for the enzymatic determination of uric acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1073172A true GB1073172A (en) | 1967-06-21 |
Family
ID=23107374
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB25127/64A Expired GB1073172A (en) | 1963-06-17 | 1964-06-17 | Improvements relating to test packs for the detection of uric acid |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US3349006A (enrdf_load_stackoverflow) |
| BE (1) | BE649402A (enrdf_load_stackoverflow) |
| BR (1) | BR6460061D0 (enrdf_load_stackoverflow) |
| CH (1) | CH473389A (enrdf_load_stackoverflow) |
| DE (1) | DE1498901C3 (enrdf_load_stackoverflow) |
| DK (1) | DK130180B (enrdf_load_stackoverflow) |
| GB (1) | GB1073172A (enrdf_load_stackoverflow) |
| NL (2) | NL6406883A (enrdf_load_stackoverflow) |
| SE (1) | SE304623B (enrdf_load_stackoverflow) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4234313A (en) | 1974-11-11 | 1980-11-18 | Burroughs Wellcome Co. | Device and method for quantitative uric acid testing |
| US11604026B2 (en) | 2019-03-14 | 2023-03-14 | Terumo Bct Biotechnologies, Llc | Lyophilization loading tray assembly and system |
| US11634257B2 (en) | 2017-10-09 | 2023-04-25 | Terumo Bct Biotechnologies, Llc | Lyophilization container and method of using same |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3649198A (en) * | 1970-05-19 | 1972-03-14 | Pfizer & Co C | Diagnostic method for the determination of uric acid in blood |
| DE2237940C3 (de) * | 1972-08-02 | 1980-12-11 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur quantitativen Bestimmung von Harnsäure |
| DE2307052C2 (de) * | 1973-02-13 | 1974-10-31 | Boehringer Mannheim Gmbh, 6800 Mannheim | Harnsäure-Standard |
| CA1048390A (en) * | 1975-02-14 | 1979-02-13 | James B. Dugle | Method, composition, and device for determining the specific gravity of a liquid |
| GB1524731A (en) * | 1976-01-15 | 1978-09-13 | Wellcome Found | Determination of uric acid |
| US5055398A (en) * | 1987-05-22 | 1991-10-08 | Kabushiki Kaisha Meidensha | Process for measuring the concentration of a component in body fluid such as urine or blood |
| US9034593B2 (en) | 2010-11-22 | 2015-05-19 | Kimberly-Clark Worldwide, Inc. | Vaginal indicator to detect biomarkers of good health |
| CN114441516A (zh) * | 2021-12-20 | 2022-05-06 | 苏州百源基因技术有限公司 | 一种尿酸检测试剂盒及其制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2990338A (en) * | 1959-11-24 | 1961-06-27 | Gibson Jacob John | Composition for determination of glucose in body fluids |
-
0
- NL NL134608D patent/NL134608C/xx active
-
1963
- 1963-06-17 US US288498A patent/US3349006A/en not_active Expired - Lifetime
-
1964
- 1964-06-11 CH CH763564A patent/CH473389A/de not_active IP Right Cessation
- 1964-06-11 DE DE1498901A patent/DE1498901C3/de not_active Expired
- 1964-06-16 SE SE7311/64A patent/SE304623B/xx unknown
- 1964-06-17 BE BE649402D patent/BE649402A/xx unknown
- 1964-06-17 NL NL6406883A patent/NL6406883A/xx unknown
- 1964-06-17 BR BR160061/64A patent/BR6460061D0/pt unknown
- 1964-06-17 GB GB25127/64A patent/GB1073172A/en not_active Expired
- 1964-06-17 DK DK305064AA patent/DK130180B/da unknown
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4234313A (en) | 1974-11-11 | 1980-11-18 | Burroughs Wellcome Co. | Device and method for quantitative uric acid testing |
| US11634257B2 (en) | 2017-10-09 | 2023-04-25 | Terumo Bct Biotechnologies, Llc | Lyophilization container and method of using same |
| US11604026B2 (en) | 2019-03-14 | 2023-03-14 | Terumo Bct Biotechnologies, Llc | Lyophilization loading tray assembly and system |
| US11609042B2 (en) | 2019-03-14 | 2023-03-21 | Terumo Bct Biotechnologies, Llc | Multi-part lyophilization container and method of use |
| US11609043B2 (en) | 2019-03-14 | 2023-03-21 | Terumo Bct Biotechnologies, Llc | Lyophilization container fill fixture, system and method of use |
| US11740019B2 (en) | 2019-03-14 | 2023-08-29 | Terumo Bct Biotechnologies, Llc | Lyophilization loading tray assembly and system |
| US11747082B2 (en) | 2019-03-14 | 2023-09-05 | Terumo Bct Biotechnologies, Llc | Multi-part lyophilization container and method of use |
| US11815311B2 (en) | 2019-03-14 | 2023-11-14 | Terumo Bct Biotechnologies, Llc | Lyophilization container fill fixture, system and method of use |
| US11994343B2 (en) | 2019-03-14 | 2024-05-28 | Terumo Bct Biotechnologies, Llc | Multi-part lyophilization container and method of use |
Also Published As
| Publication number | Publication date |
|---|---|
| DK130180B (da) | 1975-01-06 |
| DK130180C (enrdf_load_stackoverflow) | 1975-06-23 |
| DE1498901C3 (de) | 1973-10-25 |
| SE304623B (enrdf_load_stackoverflow) | 1968-09-30 |
| DE1498901B2 (de) | 1973-04-05 |
| NL134608C (enrdf_load_stackoverflow) | |
| BR6460061D0 (pt) | 1973-09-11 |
| NL6406883A (enrdf_load_stackoverflow) | 1964-12-18 |
| US3349006A (en) | 1967-10-24 |
| BE649402A (enrdf_load_stackoverflow) | 1964-10-16 |
| CH473389A (de) | 1969-05-31 |
| DE1498901A1 (de) | 1969-08-28 |
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