GB1043639A - Lubricants for compression tabletting - Google Patents
Lubricants for compression tablettingInfo
- Publication number
- GB1043639A GB1043639A GB46629/64A GB4662964A GB1043639A GB 1043639 A GB1043639 A GB 1043639A GB 46629/64 A GB46629/64 A GB 46629/64A GB 4662964 A GB4662964 A GB 4662964A GB 1043639 A GB1043639 A GB 1043639A
- Authority
- GB
- United Kingdom
- Prior art keywords
- tablets
- copolymer
- tabletting
- cellulose
- polymers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000006835 compression Effects 0.000 title abstract 5
- 238000007906 compression Methods 0.000 title abstract 5
- 239000000314 lubricant Substances 0.000 title abstract 4
- 229920001577 copolymer Polymers 0.000 abstract 6
- 229920000642 polymer Polymers 0.000 abstract 6
- 238000000034 method Methods 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 4
- -1 polytetrafluoroethylene Polymers 0.000 abstract 4
- HCDGVLDPFQMKDK-UHFFFAOYSA-N hexafluoropropylene Chemical group FC(F)=C(F)C(F)(F)F HCDGVLDPFQMKDK-UHFFFAOYSA-N 0.000 abstract 3
- 235000000346 sugar Nutrition 0.000 abstract 3
- LNAZSHAWQACDHT-XIYTZBAFSA-N (2r,3r,4s,5r,6s)-4,5-dimethoxy-2-(methoxymethyl)-3-[(2s,3r,4s,5r,6r)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxy-6-[(2r,3r,4s,5r,6r)-4,5,6-trimethoxy-2-(methoxymethyl)oxan-3-yl]oxyoxane Chemical compound CO[C@@H]1[C@@H](OC)[C@H](OC)[C@@H](COC)O[C@H]1O[C@H]1[C@H](OC)[C@@H](OC)[C@H](O[C@H]2[C@@H]([C@@H](OC)[C@H](OC)O[C@@H]2COC)OC)O[C@@H]1COC LNAZSHAWQACDHT-XIYTZBAFSA-N 0.000 abstract 2
- BQCIDUSAKPWEOX-UHFFFAOYSA-N 1,1-Difluoroethene Chemical compound FC(F)=C BQCIDUSAKPWEOX-UHFFFAOYSA-N 0.000 abstract 2
- 229920000168 Microcrystalline cellulose Polymers 0.000 abstract 2
- 239000002033 PVDF binder Substances 0.000 abstract 2
- 229920002472 Starch Polymers 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 2
- 229920000615 alginic acid Polymers 0.000 abstract 2
- 235000010443 alginic acid Nutrition 0.000 abstract 2
- 239000011248 coating agent Substances 0.000 abstract 2
- 238000000576 coating method Methods 0.000 abstract 2
- 239000007884 disintegrant Substances 0.000 abstract 2
- 229920002313 fluoropolymer Polymers 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 2
- 229920000609 methyl cellulose Polymers 0.000 abstract 2
- 239000001923 methylcellulose Substances 0.000 abstract 2
- 235000010981 methylcellulose Nutrition 0.000 abstract 2
- 229960002900 methylcellulose Drugs 0.000 abstract 2
- 235000019813 microcrystalline cellulose Nutrition 0.000 abstract 2
- 239000008108 microcrystalline cellulose Substances 0.000 abstract 2
- 229940016286 microcrystalline cellulose Drugs 0.000 abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- 229920001343 polytetrafluoroethylene Polymers 0.000 abstract 2
- 239000004810 polytetrafluoroethylene Substances 0.000 abstract 2
- 229920002981 polyvinylidene fluoride Polymers 0.000 abstract 2
- 235000019698 starch Nutrition 0.000 abstract 2
- 150000008163 sugars Chemical class 0.000 abstract 2
- 239000002278 tabletting lubricant Substances 0.000 abstract 2
- 229920000623 Cellulose acetate phthalate Polymers 0.000 abstract 1
- 239000004150 EU approved colour Substances 0.000 abstract 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 159000000007 calcium salts Chemical class 0.000 abstract 1
- 239000001768 carboxy methyl cellulose Substances 0.000 abstract 1
- 229940081734 cellulose acetate phthalate Drugs 0.000 abstract 1
- UUAGAQFQZIEFAH-UHFFFAOYSA-N chlorotrifluoroethylene Chemical group FC(F)=C(F)Cl UUAGAQFQZIEFAH-UHFFFAOYSA-N 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- ZUXNZUWOTSUBMN-UHFFFAOYSA-N hydralazine hydrochloride Chemical compound Cl.C1=CC=C2C(NN)=NN=CC2=C1 ZUXNZUWOTSUBMN-UHFFFAOYSA-N 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 229940006093 opthalmologic coloring agent diagnostic Drugs 0.000 abstract 1
- 229920002689 polyvinyl acetate Polymers 0.000 abstract 1
- 239000011118 polyvinyl acetate Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- AOJFQRQNPXYVLM-UHFFFAOYSA-N pyridine hydrochloride Substances [Cl-].C1=CC=[NH+]C=C1 AOJFQRQNPXYVLM-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 abstract 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 abstract 1
- 239000008107 starch Substances 0.000 abstract 1
- BFKJFAAPBSQJPD-UHFFFAOYSA-N tetrafluoroethene Chemical group FC(F)=C(F)F BFKJFAAPBSQJPD-UHFFFAOYSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US328494A US3340152A (en) | 1963-12-06 | 1963-12-06 | Compressed oral drug tablet granulations containing admixed therein about 1% to 15% of polyfluorocarbon type polymer lubricant powders in about 1 to 150 micron particle size |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1043639A true GB1043639A (en) | 1966-09-21 |
Family
ID=23281220
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB46629/64A Expired GB1043639A (en) | 1963-12-06 | 1964-11-16 | Lubricants for compression tabletting |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US3340152A (https=) |
| BE (1) | BE656685A (https=) |
| GB (1) | GB1043639A (https=) |
| NL (1) | NL6414134A (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3932614A (en) * | 1972-02-02 | 1976-01-13 | Fabalon, Inc. | Method of lubricating or softening the skin |
| US4087517A (en) * | 1974-10-21 | 1978-05-02 | Charles L. Wragg, Jr. | Method of dry lubricating the skin |
| US4034035A (en) * | 1975-07-14 | 1977-07-05 | Merck & Co., Inc. | Method of preparing multi-toned tablets |
| US4409118A (en) * | 1981-04-03 | 1983-10-11 | Warner-Lambert Company | Tablet forming cleanser composition and method of preparation |
| US4405486A (en) * | 1981-08-31 | 1983-09-20 | Warner-Lambert Company | Method for preparing granulated perborate salts containing a polymeric fluorocarbon |
| DE3269396D1 (en) * | 1982-08-25 | 1986-04-03 | Warner Lambert Co | A granulated perborate salt product, and process for producing the same |
| USRE32771E (en) * | 1983-04-22 | 1988-10-25 | Warner-Lambert Company | Denture cleaner having improved dissolution time and clarity and method of preparation |
| EP0253772A3 (en) * | 1986-07-15 | 1989-07-19 | Warner-Lambert Company | Denture cleansing and/or washing compositions containing a bleach activator |
| US4844908A (en) * | 1986-11-27 | 1989-07-04 | Duphar International Research B.V. | Method of preparing tablets with clovoxamine fumarate and tablets thus prepared |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2552027A (en) * | 1948-01-17 | 1951-05-08 | American Cyanamid Co | Casting gelatin tablets |
| US2573639A (en) * | 1949-12-02 | 1951-10-30 | Myron A Coler | Manufacture of porous articles from trifluorochloroethylene polymer |
| US2936301A (en) * | 1956-11-15 | 1960-05-10 | Du Pont | Polytetrafluoroethylene granular powders |
| US3004294A (en) * | 1958-03-12 | 1961-10-17 | Hoechst Ag | Process for the manufacture of granular products |
| US2939178A (en) * | 1958-04-30 | 1960-06-07 | Continental Diamond Fibre Corp | Process for molding sintered polytetrafluoroethylene articles |
| US3096248A (en) * | 1959-04-06 | 1963-07-02 | Rexall Drug & Chemical Company | Method of making an encapsulated tablet |
| US3042531A (en) * | 1959-12-09 | 1962-07-03 | Leslie Salt Company | Method of making a compressed tablet |
| US3247066A (en) * | 1962-09-12 | 1966-04-19 | Parke Davis & Co | Controlled release dosage form containing water-swellable beadlet |
| US3260774A (en) * | 1963-01-21 | 1966-07-12 | Tensolite Insulated Wire Co In | Method for the continuous extrusion of unsintered polytetrafluoroethylene powder |
| US3312764A (en) * | 1964-10-22 | 1967-04-04 | Haveg Industries Inc | Cold powder molding of polytetrafluoroethylene |
-
1963
- 1963-12-06 US US328494A patent/US3340152A/en not_active Expired - Lifetime
-
1964
- 1964-11-16 GB GB46629/64A patent/GB1043639A/en not_active Expired
- 1964-12-04 NL NL6414134A patent/NL6414134A/xx unknown
- 1964-12-04 BE BE656685A patent/BE656685A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL6414134A (https=) | 1965-06-07 |
| US3340152A (en) | 1967-09-05 |
| BE656685A (https=) | 1965-06-04 |
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