GB1018775A - Pyrazine compositions - Google Patents

Pyrazine compositions

Info

Publication number
GB1018775A
GB1018775A GB4646262A GB4646262A GB1018775A GB 1018775 A GB1018775 A GB 1018775A GB 4646262 A GB4646262 A GB 4646262A GB 4646262 A GB4646262 A GB 4646262A GB 1018775 A GB1018775 A GB 1018775A
Authority
GB
United Kingdom
Prior art keywords
pharmaceutically
acceptable
compound
formula
alkyl group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4646262A
Inventor
Wilson Boyd Lutz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Pharmaceutical Co filed Critical Warner Lambert Pharmaceutical Co
Priority to GB4646262A priority Critical patent/GB1018775A/en
Publication of GB1018775A publication Critical patent/GB1018775A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/20—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention comprises pyrazine derivatives of the formula <FORM:1018775/C2/1> wherein R1 is a C1- 6-alkyl group, R2\t is a piperidino, pyrrolidino, morpholino or hexamethyleneimino group and one of R3 and R4 is a hydrogen atom and the other is a hydrogen atom or a C1- 6 alkyl group, and pharmaceutically-acceptable, non-toxic acid-addition salts thereof. The compounds are prepared by reacting a compound of the formula <FORM:1018775/C2/2> wherein X is a halogen atom, with piperidine, pyrrolidine, morpholine or hexamethyleneimine, preferably in the presence of an alkali metal hydroxide. Pharmaceutical compositions, having anti-depressant, muscle relaxant and gastric antisecretory activity, comprise a compound of the invention, or a pharmaceutically-acceptable, non-toxic acid-addition salt thereof, together with a pharmaceutically-acceptable carrier. They may take the form of tablets, capsules, solutions, suspensions, suppositories or elixirs.
GB4646262A 1962-12-10 1962-12-10 Pyrazine compositions Expired GB1018775A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB4646262A GB1018775A (en) 1962-12-10 1962-12-10 Pyrazine compositions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4646262A GB1018775A (en) 1962-12-10 1962-12-10 Pyrazine compositions

Publications (1)

Publication Number Publication Date
GB1018775A true GB1018775A (en) 1966-02-02

Family

ID=10441370

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4646262A Expired GB1018775A (en) 1962-12-10 1962-12-10 Pyrazine compositions

Country Status (1)

Country Link
GB (1) GB1018775A (en)

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