GB1007751A - Therapeutic glucosides and method of obtaining them - Google Patents

Therapeutic glucosides and method of obtaining them

Info

Publication number
GB1007751A
GB1007751A GB1486162A GB1486162A GB1007751A GB 1007751 A GB1007751 A GB 1007751A GB 1486162 A GB1486162 A GB 1486162A GB 1486162 A GB1486162 A GB 1486162A GB 1007751 A GB1007751 A GB 1007751A
Authority
GB
United Kingdom
Prior art keywords
mixture
anthocyanidin
glucosides
yeast
fermentation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1486162A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratories Merck Sharp and Dohme Chibret SAS
Original Assignee
Laboratoires Chibret SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR859092A external-priority patent/FR1369M/en
Priority claimed from FR859093A external-priority patent/FR1300869A/en
Application filed by Laboratoires Chibret SA filed Critical Laboratoires Chibret SA
Publication of GB1007751A publication Critical patent/GB1007751A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
    • C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06—Benzopyran radicals
    • C07H17/065—Benzo[b]pyrans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

Anthocyanidin glycosides are isolated from a mixture of anthocyanidin glycosides and sugars by fermenting the sugar content of the mixture by means of yeast which will ferment the sugars but which will not attack the glucosides and separating the anthocyanidin glucosides from the fermented mixture. The mixture to be fermented may be the juice or an extract of plants or fruit such as the juice or an extract from bilberries. It is preferable to lyophilize and acclimatize the yeast to the anthocyanidin glycoside content of the mixture before fermentation. A suitable yeast is Saccharomyces oviformis. The fermentation may be carried out under partial aerobic conditions and carbon dioxide formed during the fermentation is preferably removed from the vicinity of the fermenting mixture.ALSO:Therapeutic compositions useful for improving visual acuity and for the treatment of vascular diseases which increase the fragility and the permeability of capillary walls contain as the active ingredient anthocyanidin glucosides and an inert diluent or carrier. The composition may be administered in the form of tablets, drops or injectable solution.
GB1486162A 1961-04-18 1962-04-17 Therapeutic glucosides and method of obtaining them Expired GB1007751A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR859092A FR1369M (en) 1961-04-18 1961-04-18 New products for the treatment of visual acuity.
FR859093A FR1300869A (en) 1961-04-18 1961-04-18 Improvements to processes for obtaining glucosides, in particular anthocyanin glucosides

Publications (1)

Publication Number Publication Date
GB1007751A true GB1007751A (en) 1965-10-22

Family

ID=26190149

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1486162A Expired GB1007751A (en) 1961-04-18 1962-04-17 Therapeutic glucosides and method of obtaining them

Country Status (6)

Country Link
BE (1) BE615972A (en)
CH (1) CH432547A (en)
DE (1) DE1287083B (en)
ES (1) ES276335A1 (en)
GB (1) GB1007751A (en)
LU (1) LU41497A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09221484A (en) * 1996-02-14 1997-08-26 Kikkoman Corp Production of proanthocyanidin
US7658963B1 (en) * 1999-07-02 2010-02-09 Meiji Seika Kaisha, Ltd. Compositions for foods, process for producing the same and functional foods and drinks containing the same

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09221484A (en) * 1996-02-14 1997-08-26 Kikkoman Corp Production of proanthocyanidin
EP0790314A3 (en) * 1996-02-14 1999-04-07 Kikkoman Corporation Process for the preparation of proanthocyanidins
US7658963B1 (en) * 1999-07-02 2010-02-09 Meiji Seika Kaisha, Ltd. Compositions for foods, process for producing the same and functional foods and drinks containing the same
US8722126B2 (en) 1999-07-02 2014-05-13 Meiji Co., Ltd. Compositions for food, process for producing the same, and functional foods and drinks containing the same

Also Published As

Publication number Publication date
DE1287083B (en) 1969-01-16
CH432547A (en) 1967-03-31
LU41497A1 (en) 1962-06-05
BE615972A (en) 1962-07-31
ES276335A1 (en) 1962-10-16

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