GB0915515D0 - Treatment of vasculoproliferative conditions - Google Patents

Treatment of vasculoproliferative conditions

Info

Publication number
GB0915515D0
GB0915515D0 GBGB0915515.1A GB0915515A GB0915515D0 GB 0915515 D0 GB0915515 D0 GB 0915515D0 GB 0915515 A GB0915515 A GB 0915515A GB 0915515 D0 GB0915515 D0 GB 0915515D0
Authority
GB
United Kingdom
Prior art keywords
treatment
vasculoproliferative
conditions
vasculoproliferative conditions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0915515.1A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCL Business Ltd
Original Assignee
UCL Business Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UCL Business Ltd filed Critical UCL Business Ltd
Priority to GBGB0915515.1A priority Critical patent/GB0915515D0/en
Publication of GB0915515D0 publication Critical patent/GB0915515D0/en
Priority to AU2010290986A priority patent/AU2010290986B2/en
Priority to US13/393,531 priority patent/US8790647B2/en
Priority to CA2771965A priority patent/CA2771965C/en
Priority to JP2012527383A priority patent/JP2013503621A/ja
Priority to CN201080039413.0A priority patent/CN102596998B/zh
Priority to ES10754361.3T priority patent/ES2647359T3/es
Priority to EP10754361.3A priority patent/EP2473526B1/en
Priority to PCT/GB2010/001681 priority patent/WO2011027129A1/en
Priority to US14/312,593 priority patent/US9708397B2/en
Priority to JP2015241950A priority patent/JP6242847B2/ja
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/495—Transforming growth factor [TGF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
    • C12N2310/141—MicroRNAs, miRNAs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00—Applications; Uses
    • C12N2320/30—Special therapeutic applications

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GBGB0915515.1A 2009-09-04 2009-09-04 Treatment of vasculoproliferative conditions Ceased GB0915515D0 (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
GBGB0915515.1A GB0915515D0 (en) 2009-09-04 2009-09-04 Treatment of vasculoproliferative conditions
PCT/GB2010/001681 WO2011027129A1 (en) 2009-09-04 2010-09-06 Treatment of vasculoproliferative conditions
JP2012527383A JP2013503621A (ja) 2009-09-04 2010-09-06 血管増殖性疾患の治療
US13/393,531 US8790647B2 (en) 2009-09-04 2010-09-06 Treatment of vasculoproliferative conditions with Lrg1 anatgonists
CA2771965A CA2771965C (en) 2009-09-04 2010-09-06 Treatment of vasculoproliferative conditions
AU2010290986A AU2010290986B2 (en) 2009-09-04 2010-09-06 Treatment of vasculoproliferative conditions
CN201080039413.0A CN102596998B (zh) 2009-09-04 2010-09-06 血管增殖病症的治疗
ES10754361.3T ES2647359T3 (es) 2009-09-04 2010-09-06 Tratamiento de afecciones vasculoproliferativas
EP10754361.3A EP2473526B1 (en) 2009-09-04 2010-09-06 Treatment of vasculoproliferative conditions
US14/312,593 US9708397B2 (en) 2009-09-04 2014-06-23 Treatment of vasculoproliferative conditions with Lrg1 antagonists
JP2015241950A JP6242847B2 (ja) 2009-09-04 2015-12-11 血管増殖性疾患の治療

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0915515.1A GB0915515D0 (en) 2009-09-04 2009-09-04 Treatment of vasculoproliferative conditions

Publications (1)

Publication Number Publication Date
GB0915515D0 true GB0915515D0 (en) 2009-10-07

Family

ID=41203240

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0915515.1A Ceased GB0915515D0 (en) 2009-09-04 2009-09-04 Treatment of vasculoproliferative conditions

Country Status (9)

Country Link
US (2) US8790647B2 (enExample)
EP (1) EP2473526B1 (enExample)
JP (2) JP2013503621A (enExample)
CN (1) CN102596998B (enExample)
AU (1) AU2010290986B2 (enExample)
CA (1) CA2771965C (enExample)
ES (1) ES2647359T3 (enExample)
GB (1) GB0915515D0 (enExample)
WO (1) WO2011027129A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5717021B2 (ja) * 2009-12-03 2015-05-13 独立行政法人医薬基盤研究所 血管新生誘導分子
CA2866696A1 (en) 2012-03-09 2013-09-12 Ucl Business Plc Treatment of cancer
TWI498425B (zh) * 2013-01-08 2015-09-01 Nat Univ Tsing Hua 層析濾紙型酵素連結免疫吸附分析法
JP6226315B2 (ja) * 2013-04-11 2017-11-08 国立大学法人高知大学 炎症性疾患の予防・治療剤、並びに炎症性疾患予防・治療薬のスクリーニング方法
HK1219144A1 (zh) 2013-06-08 2017-03-24 苹果公司 用於同步兩個或更多個顯示器的設備、方法和圖形用戶界面
CN103926413A (zh) * 2014-04-28 2014-07-16 刘红莉 一种用尿液进行癌症快速检测的试剂条的制备方法
US9840553B2 (en) 2014-06-28 2017-12-12 Kodiak Sciences Inc. Dual PDGF/VEGF antagonists
JP6388350B2 (ja) * 2014-09-17 2018-09-12 東芝メモリ株式会社 半導体装置
JP6675605B2 (ja) * 2014-10-10 2020-04-01 国立大学法人高知大学 細胞遊走調節に関する疾患の予防・治療剤および肺間質の疾患の疾患活動性判定・予後評価
WO2016110782A1 (en) 2015-01-05 2016-07-14 University Of Oslo Prostate cancer markers and uses thereof
GB201503438D0 (en) * 2015-02-27 2015-04-15 Ucl Business Plc Antibodies
CA3010056A1 (en) 2015-12-30 2017-07-06 Kodiak Sciences Inc. Antibodies and conjugates thereof
WO2018021778A1 (ko) * 2016-07-28 2018-02-01 인하대학교 산학협력단 Lrg1 당단백질을 포함하는 융합 단백질을 함유하는 발기부전, 허혈성 질환 또는 말초 신경질환의 예방 또는 치료용 조성물
CN112203679A (zh) 2018-03-02 2021-01-08 科达制药股份有限公司 Il-6抗体及其融合构建体和缀合物
CN114786731A (zh) 2019-10-10 2022-07-22 科达制药股份有限公司 治疗眼部病症的方法
KR102661295B1 (ko) * 2021-01-22 2024-04-30 기초과학연구원 탈당화된 lrg1 당단백질 및 lrg1 당단백질 변이체, 및 이의 용도
KR20250168499A (ko) 2023-04-07 2025-12-02 다이애고널 테라퓨틱스 인코포레이티드 액티빈 a 수용체 유사 유형 1(alk1)에 대한 이중 특이적 효현성 항체

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Also Published As

Publication number Publication date
JP6242847B2 (ja) 2017-12-06
CA2771965C (en) 2018-12-11
JP2016104757A (ja) 2016-06-09
EP2473526A1 (en) 2012-07-11
WO2011027129A1 (en) 2011-03-10
WO2011027129A9 (en) 2012-06-14
EP2473526B1 (en) 2017-08-09
US20140377277A1 (en) 2014-12-25
CN102596998A (zh) 2012-07-18
CA2771965A1 (en) 2011-03-10
US9708397B2 (en) 2017-07-18
AU2010290986B2 (en) 2016-02-11
ES2647359T3 (es) 2017-12-21
CN102596998B (zh) 2016-03-16
US8790647B2 (en) 2014-07-29
AU2010290986A1 (en) 2012-04-05
US20120231002A1 (en) 2012-09-13
JP2013503621A (ja) 2013-02-04

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AT Applications terminated before publication under section 16(1)