GB0815484D0 - Antibacterial agents - Google Patents

Antibacterial agents

Info

Publication number
GB0815484D0
GB0815484D0 GBGB0815484.1A GB0815484A GB0815484D0 GB 0815484 D0 GB0815484 D0 GB 0815484D0 GB 0815484 A GB0815484 A GB 0815484A GB 0815484 D0 GB0815484 D0 GB 0815484D0
Authority
GB
United Kingdom
Prior art keywords
antibacterial agents
antibacterial
agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0815484.1A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Katholieke Universiteit Leuven
Original Assignee
Katholieke Universiteit Leuven
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Katholieke Universiteit Leuven filed Critical Katholieke Universiteit Leuven
Priority to GBGB0815484.1A priority Critical patent/GB0815484D0/en
Publication of GB0815484D0 publication Critical patent/GB0815484D0/en
Priority to CN200980142373.XA priority patent/CN102197132B/zh
Priority to US13/061,053 priority patent/US9809808B2/en
Priority to PL09782176T priority patent/PL2331687T3/pl
Priority to HK11112268.7A priority patent/HK1157818B/en
Priority to JP2011524360A priority patent/JP5153943B2/ja
Priority to AU2009286760A priority patent/AU2009286760B2/en
Priority to MX2011001957A priority patent/MX2011001957A/es
Priority to KR1020117006983A priority patent/KR101473271B1/ko
Priority to CA2735077A priority patent/CA2735077C/en
Priority to PCT/EP2009/060947 priority patent/WO2010023207A2/en
Priority to ES09782176T priority patent/ES2395357T3/es
Priority to DK09782176.3T priority patent/DK2331687T3/da
Priority to EP09782176A priority patent/EP2331687B1/en
Priority to BRPI0917508-3A priority patent/BRPI0917508A2/pt
Priority to EA201100312A priority patent/EA024794B1/ru
Priority to IL211441A priority patent/IL211441A/en
Priority to JP2012265070A priority patent/JP5571757B2/ja
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2462—Lysozyme (3.2.1.17)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GBGB0815484.1A 2008-08-26 2008-08-26 Antibacterial agents Ceased GB0815484D0 (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
GBGB0815484.1A GB0815484D0 (en) 2008-08-26 2008-08-26 Antibacterial agents
EA201100312A EA024794B1 (ru) 2008-08-26 2009-08-25 Вариант эндолизина со встроенным катионным пептидом с активностью, разрушающей липополисахарид
KR1020117006983A KR101473271B1 (ko) 2008-08-26 2009-08-25 항균제
PCT/EP2009/060947 WO2010023207A2 (en) 2008-08-26 2009-08-25 Antimicrobial agents
PL09782176T PL2331687T3 (pl) 2008-08-26 2009-08-25 Środki przeciwdrobnoustrojowe
HK11112268.7A HK1157818B (en) 2008-08-26 2009-08-25 Antimicrobial agents
JP2011524360A JP5153943B2 (ja) 2008-08-26 2009-08-25 抗微生物剤
AU2009286760A AU2009286760B2 (en) 2008-08-26 2009-08-25 Antimicrobial agents
MX2011001957A MX2011001957A (es) 2008-08-26 2009-08-25 Agentes antimicrobianos.
CN200980142373.XA CN102197132B (zh) 2008-08-26 2009-08-25 抗微生物剂
CA2735077A CA2735077C (en) 2008-08-26 2009-08-25 Antimicrobial agents
US13/061,053 US9809808B2 (en) 2008-08-26 2009-08-25 Antimicrobial agents
ES09782176T ES2395357T3 (es) 2008-08-26 2009-08-25 Agentes antimicrobianos
DK09782176.3T DK2331687T3 (da) 2008-08-26 2009-08-25 Antimikrobielle midler
EP09782176A EP2331687B1 (en) 2008-08-26 2009-08-25 Antimicrobial agents
BRPI0917508-3A BRPI0917508A2 (pt) 2008-08-26 2009-08-25 Agentes antimicrobianos
IL211441A IL211441A (en) 2008-08-26 2011-02-27 Variety of endolysin, methods of manufacture and use thereof
JP2012265070A JP5571757B2 (ja) 2008-08-26 2012-12-04 抗微生物剤

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0815484.1A GB0815484D0 (en) 2008-08-26 2008-08-26 Antibacterial agents

Publications (1)

Publication Number Publication Date
GB0815484D0 true GB0815484D0 (en) 2008-10-01

Family

ID=39846783

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0815484.1A Ceased GB0815484D0 (en) 2008-08-26 2008-08-26 Antibacterial agents

Country Status (16)

Country Link
US (1) US9809808B2 (cg-RX-API-DMAC7.html)
EP (1) EP2331687B1 (cg-RX-API-DMAC7.html)
JP (2) JP5153943B2 (cg-RX-API-DMAC7.html)
KR (1) KR101473271B1 (cg-RX-API-DMAC7.html)
CN (1) CN102197132B (cg-RX-API-DMAC7.html)
AU (1) AU2009286760B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0917508A2 (cg-RX-API-DMAC7.html)
CA (1) CA2735077C (cg-RX-API-DMAC7.html)
DK (1) DK2331687T3 (cg-RX-API-DMAC7.html)
EA (1) EA024794B1 (cg-RX-API-DMAC7.html)
ES (1) ES2395357T3 (cg-RX-API-DMAC7.html)
GB (1) GB0815484D0 (cg-RX-API-DMAC7.html)
IL (1) IL211441A (cg-RX-API-DMAC7.html)
MX (1) MX2011001957A (cg-RX-API-DMAC7.html)
PL (1) PL2331687T3 (cg-RX-API-DMAC7.html)
WO (1) WO2010023207A2 (cg-RX-API-DMAC7.html)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0815484D0 (en) 2008-08-26 2008-10-01 Univ Leuven Kath Antibacterial agents
EP3714895A3 (en) 2009-06-26 2020-11-25 Lysando AG Antimicrobial agents
WO2010149795A1 (en) * 2009-06-26 2010-12-29 Lysando Holding Establishment Antimicrobial agents
EA024253B1 (ru) * 2009-08-24 2016-08-31 Катхолике Университейт Лёвен, К.У. Лёвен Р Энд Д Литический полипептид с пептидогликангидролазной активностью и его применение против инфекций, вызванных грамотрицательными бактериями
DK2563916T3 (en) * 2010-04-27 2015-10-05 Lysando Ag METHOD FOR REDUCING biofilms
PT3443970T (pt) * 2010-09-17 2020-10-09 Technophage Investig E Desenvolvimento Em Biotecnologia Sa Fagos antibacterianos, péptidos fágicos e métodos de utilização dos mesmos
GB201018518D0 (en) 2010-11-03 2010-12-15 Univ Leuven Kath Novel endolysin
EP2468856A1 (en) * 2010-12-23 2012-06-27 Lysando Aktiengesellschaft Antimicrobial Agents
CN108578685A (zh) * 2011-04-21 2018-09-28 洛克菲勒大学 用于革兰氏阳性菌检测和治疗的链球菌属细菌噬菌体溶素
WO2012146738A1 (en) * 2011-04-27 2012-11-01 Lysando Holding Ag New antimicrobial agents
US9068204B2 (en) 2013-03-15 2015-06-30 The United States Of America, As Represented By The Secretary Of Agriculture Peptidoglycan hydrolase antimicrobials for eradicating lactobacilli that contaminate and reduce ethanol yields in biofuel fermentation
WO2015070912A1 (en) 2013-11-14 2015-05-21 Lysando Ag Modified el188 endolysin sequence
WO2015070911A1 (en) * 2013-11-14 2015-05-21 Lysando Ag Modified kz144 endolysin sequence
EP3105322B1 (en) 2014-02-14 2018-12-12 Lysando AG Antimicrobial agents
AU2015243359B2 (en) * 2014-04-08 2020-03-12 Lysando Ag Pharmaceutical composition against chronic bacterial infections
GB2543453A (en) 2014-06-26 2017-04-19 Univ Rockefeller Acinetobacter lysins
CN104762285B (zh) * 2015-04-23 2017-10-27 武汉菲吉乐科生物科技有限公司 一种自内裂解大肠杆菌的裂解酶及其应用
JP7033596B2 (ja) * 2016-12-16 2022-03-10 ウニベルシダージ ド ミーニョ 新規エンドリシン
US11208643B2 (en) * 2017-04-03 2021-12-28 Sasinapas Co., Ltd. Engineered gram-negative endolysins
BR112020011433A2 (pt) * 2017-12-12 2020-12-01 Contrafect Corporation identificação de lisinas e seus derivados com atividade bacteriana contra pseudomonas aeruginosa
JP7515409B2 (ja) 2018-05-30 2024-07-12 ライサンド アーゲー 新規抗微生物融合タンパク質
AU2019276253A1 (en) 2018-05-30 2020-11-26 Lysando Ag Novel antimicrobial proteins
AU2020268752B2 (en) * 2019-05-08 2025-12-18 BioNTech SE Novel gardnerella endolysins and uses thereof
WO2023225518A2 (en) * 2022-05-16 2023-11-23 The Broad Institute, Inc. Engineered pnma proteins and delivery systems thereof
CN117737001B (zh) * 2022-12-27 2024-08-09 菲吉乐科(南京)生物科技有限公司 一种防治犬细菌性腹泻的大肠杆菌噬菌体及其应用
CN118620800B (zh) * 2024-08-08 2024-11-12 中国兽医药品监察所 一株鼻疽伯克霍尔德氏菌及其应用

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GB2255561B (en) * 1991-04-20 1995-06-21 Agricultural & Food Res Lysins from bacteriophages
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PT778733E (pt) 1994-09-01 2001-06-29 Novozymes As Composicao proteica basica para matar ou inibir celulas microbianas
US6503881B2 (en) 1996-08-21 2003-01-07 Micrologix Biotech Inc. Compositions and methods for treating infections using cationic peptides alone or in combination with antibiotics
US6428784B1 (en) * 1997-10-31 2002-08-06 New Horizons Diagnostics Corp Vaginal suppository for treating group B Streptococcus infection
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AU5553600A (en) 1999-06-23 2001-01-31 Ppl Therapeutics (Scotland) Ltd Fusion proteins incorporating lysozyme
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WO2005108563A2 (en) 2004-04-19 2005-11-17 University Of Chicago Peptidoglycan-hydrolyzing protein encoded by bacteriophage n4
US7572602B1 (en) 2004-12-03 2009-08-11 The United States Of America As Represented By The Secretary Of Agriculture Nucleic acid encoding endolysin fusion protein
DE102005040347A1 (de) 2005-08-25 2007-03-01 Profos Ag Verfahren und Mittel zur Anreicherung, Entfernung und zum Nachweis von Listerien
EP2004215B1 (en) 2006-03-31 2010-06-09 The University Court of the University of St. Andrews Anti-microbial compositions comprising a cationic peptide and a glycylglycine endopeptidase
DE102006061002A1 (de) * 2006-12-22 2008-06-26 Profos Ag Verfahren und Mittel zur Anreicherung, Entfernung und zum Nachweis von gram-positiven Bakterien
EP3327030B1 (en) 2007-09-25 2021-07-21 Pastoral Greenhouse Gas Research LTD Vaccines and vaccine components for inhibition of microbial cells
US20100310522A1 (en) 2007-11-26 2010-12-09 Plant Bioscience Limited Novel Polypeptides Having Endolysin Activity and Uses Thereof
EP2318531A4 (en) 2008-07-24 2011-11-09 Us Agriculture TO RESISTANCE DEVELOPMENT REFRACTORY ANTIMICROBIAL ACTIVE SUBSTANCES
EP2157100A1 (en) 2008-08-19 2010-02-24 Profos AG Artificial peptidoglycan lysing enzymes and peptidoglycan binding proteins
GB0815484D0 (en) 2008-08-26 2008-10-01 Univ Leuven Kath Antibacterial agents
WO2010091294A2 (en) 2009-02-05 2010-08-12 The Regents Of The University Of California New targeted antimicrobial moieties
EP3714895A3 (en) 2009-06-26 2020-11-25 Lysando AG Antimicrobial agents
EA024253B1 (ru) 2009-08-24 2016-08-31 Катхолике Университейт Лёвен, К.У. Лёвен Р Энд Д Литический полипептид с пептидогликангидролазной активностью и его применение против инфекций, вызванных грамотрицательными бактериями
DK2563916T3 (en) 2010-04-27 2015-10-05 Lysando Ag METHOD FOR REDUCING biofilms

Also Published As

Publication number Publication date
CA2735077A1 (en) 2010-03-04
HK1157818A1 (en) 2012-07-06
EA024794B1 (ru) 2016-10-31
ES2395357T3 (es) 2013-02-12
US20110243915A1 (en) 2011-10-06
AU2009286760B2 (en) 2015-08-27
CN102197132B (zh) 2016-01-13
CN102197132A (zh) 2011-09-21
JP2013081465A (ja) 2013-05-09
MX2011001957A (es) 2011-06-20
JP2012500642A (ja) 2012-01-12
BRPI0917508A2 (pt) 2015-08-04
JP5153943B2 (ja) 2013-02-27
DK2331687T3 (da) 2013-01-07
EP2331687A2 (en) 2011-06-15
KR20110049883A (ko) 2011-05-12
JP5571757B2 (ja) 2014-08-13
PL2331687T3 (pl) 2013-02-28
US9809808B2 (en) 2017-11-07
WO2010023207A3 (en) 2010-07-15
AU2009286760A1 (en) 2010-03-04
WO2010023207A2 (en) 2010-03-04
EP2331687B1 (en) 2012-09-19
EA201100312A1 (ru) 2011-10-31
IL211441A (en) 2015-04-30
KR101473271B1 (ko) 2014-12-16
CA2735077C (en) 2019-04-09

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)