GB0705159D0 - Process for making crystals - Google Patents

Process for making crystals

Info

Publication number
GB0705159D0
GB0705159D0 GBGB0705159.2A GB0705159A GB0705159D0 GB 0705159 D0 GB0705159 D0 GB 0705159D0 GB 0705159 A GB0705159 A GB 0705159A GB 0705159 D0 GB0705159 D0 GB 0705159D0
Authority
GB
United Kingdom
Prior art keywords
making crystals
crystals
making
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0705159.2A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Prosonix Ltd
Original Assignee
Prosonix Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prosonix Ltd filed Critical Prosonix Ltd
Priority to GBGB0705159.2A priority Critical patent/GB0705159D0/en
Publication of GB0705159D0 publication Critical patent/GB0705159D0/en
Priority to BRPI0809275-3A2A priority patent/BRPI0809275A2/pt
Priority to JP2009554087A priority patent/JP2010522154A/ja
Priority to GB0804995.9A priority patent/GB2447761B/en
Priority to US12/531,322 priority patent/US9162160B2/en
Priority to RU2009138325/05A priority patent/RU2456066C2/ru
Priority to ES08719036T priority patent/ES2701728T3/es
Priority to EP08719036.9A priority patent/EP2134457B1/en
Priority to CN200880008925.3A priority patent/CN101636223B/zh
Priority to CA2680105A priority patent/CA2680105C/en
Priority to PCT/GB2008/050191 priority patent/WO2008114052A1/en
Priority to IL200802A priority patent/IL200802A/en
Priority to JP2014016565A priority patent/JP5808830B2/ja
Priority to US14/854,750 priority patent/US10143991B2/en
Ceased legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/08—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor
    • B01J19/10—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor employing sonic or ultrasonic vibrations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/005—Selection of auxiliary, e.g. for control of crystallisation nuclei, of crystal growth, of adherence to walls; Arrangements for introduction thereof
    • B01D9/0054—Use of anti-solvent
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/0081—Use of vibrations, e.g. ultrasound
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/02—Crystallisation from solutions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/18—Stationary reactors having moving elements inside
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/18—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic using a vibrating apparatus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/38—Separation; Purification; Stabilisation; Use of additives
    • C07C227/40—Separation; Purification
    • C07C227/42—Crystallisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00049—Controlling or regulating processes
    • B01J2219/00051—Controlling the temperature
    • B01J2219/00074—Controlling the temperature by indirect heating or cooling employing heat exchange fluids
    • B01J2219/00105—Controlling the temperature by indirect heating or cooling employing heat exchange fluids part or all of the reactants being heated or cooled outside the reactor while recycling
    • B01J2219/0011—Controlling the temperature by indirect heating or cooling employing heat exchange fluids part or all of the reactants being heated or cooled outside the reactor while recycling involving reactant liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00049—Controlling or regulating processes
    • B01J2219/00051—Controlling the temperature
    • B01J2219/00074—Controlling the temperature by indirect heating or cooling employing heat exchange fluids
    • B01J2219/00105—Controlling the temperature by indirect heating or cooling employing heat exchange fluids part or all of the reactants being heated or cooled outside the reactor while recycling
    • B01J2219/00114—Controlling the temperature by indirect heating or cooling employing heat exchange fluids part or all of the reactants being heated or cooled outside the reactor while recycling involving reactant slurries

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
GBGB0705159.2A 2007-03-19 2007-03-19 Process for making crystals Ceased GB0705159D0 (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
GBGB0705159.2A GB0705159D0 (en) 2007-03-19 2007-03-19 Process for making crystals
PCT/GB2008/050191 WO2008114052A1 (en) 2007-03-19 2008-03-18 Process for making crystals
ES08719036T ES2701728T3 (es) 2007-03-19 2008-03-18 Proceso para preparar cristales
CN200880008925.3A CN101636223B (zh) 2007-03-19 2008-03-18 制备晶体的方法
GB0804995.9A GB2447761B (en) 2007-03-19 2008-03-18 Process for making crystals
US12/531,322 US9162160B2 (en) 2007-03-19 2008-03-18 Process for making crystals
RU2009138325/05A RU2456066C2 (ru) 2007-03-19 2008-03-18 Способ получения кристаллов
BRPI0809275-3A2A BRPI0809275A2 (pt) 2007-03-19 2008-03-18 Processo para preparar partículas cristalinas de um princípio ativo na presença de irradiação ultrassônica.
EP08719036.9A EP2134457B1 (en) 2007-03-19 2008-03-18 Process for making crystals
JP2009554087A JP2010522154A (ja) 2007-03-19 2008-03-18 結晶の製造方法
CA2680105A CA2680105C (en) 2007-03-19 2008-03-18 Process for making crystals via ultrasonic irradiation of a closed loop
IL200802A IL200802A (en) 2007-03-19 2009-09-08 A process for making crystals
JP2014016565A JP5808830B2 (ja) 2007-03-19 2014-01-31 結晶の製造方法
US14/854,750 US10143991B2 (en) 2007-03-19 2015-09-15 Process for making crystals

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0705159.2A GB0705159D0 (en) 2007-03-19 2007-03-19 Process for making crystals

Publications (1)

Publication Number Publication Date
GB0705159D0 true GB0705159D0 (en) 2007-04-25

Family

ID=38008612

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB0705159.2A Ceased GB0705159D0 (en) 2007-03-19 2007-03-19 Process for making crystals
GB0804995.9A Active GB2447761B (en) 2007-03-19 2008-03-18 Process for making crystals

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB0804995.9A Active GB2447761B (en) 2007-03-19 2008-03-18 Process for making crystals

Country Status (11)

Country Link
US (2) US9162160B2 (enExample)
EP (1) EP2134457B1 (enExample)
JP (2) JP2010522154A (enExample)
CN (1) CN101636223B (enExample)
BR (1) BRPI0809275A2 (enExample)
CA (1) CA2680105C (enExample)
ES (1) ES2701728T3 (enExample)
GB (2) GB0705159D0 (enExample)
IL (1) IL200802A (enExample)
RU (1) RU2456066C2 (enExample)
WO (1) WO2008114052A1 (enExample)

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GB0705159D0 (en) * 2007-03-19 2007-04-25 Prosonix Ltd Process for making crystals
MX2011000410A (es) * 2008-07-18 2011-03-24 Prosonix Ltd Proceso para mejorar la cristalinidad de particulas de fluticasona.
GB0900080D0 (en) * 2009-01-06 2009-02-11 Prosonix Ltd An apparatus and process for producing crystals
GB0918431D0 (en) 2009-10-21 2009-12-09 Prosonix Ltd Process for improving crystallinity
EP2360147A1 (en) 2010-02-22 2011-08-24 CHIESI FARMACEUTICI S.p.A. Process for preparing crystalline particles of a salt of 8-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino] ethyl]-2(1H)-quinolinone (carmoterol)
BR112012024059B1 (pt) 2010-04-01 2021-06-01 Chiesi Farmaceutici S.P.A. Processo de preparo de um excipiente para composições farmacêuticas em pó para inalação, partículas carreadoras para uma formulação farmacêutica de pó seco, composição farmacêutica em forma de pó seco para inalação e inalador de pó seco
US9278867B2 (en) 2010-12-30 2016-03-08 Yava Technologies Inc. Transition metal compound particles and methods of production
EP2500072A1 (en) 2011-03-15 2012-09-19 LEK Pharmaceuticals d.d. A novel process of residual solvent removal
GB201113662D0 (en) 2011-08-08 2011-09-21 Prosonix Ltd Pharmaceutical compositions
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GB201301721D0 (en) * 2013-01-31 2013-03-20 Prosonix Ltd Pharmaceutical Preparations
EP2950792A1 (en) 2013-01-31 2015-12-09 Prosonix Limited Pharmaceutical compositions comprising multi-component crystalline particles suitable for use in inhalation therapy
CN103172476A (zh) * 2013-04-08 2013-06-26 中国工程物理研究院化工材料研究所 一种亚微米颗粒1-氧-二氨基-3，5-二硝基吡嗪炸药的制备方法
US9469548B2 (en) * 2015-02-20 2016-10-18 Hydro Dynamics, Inc. Continuous hydrodynamic cavitation crystallization
CN105037253A (zh) * 2015-05-27 2015-11-11 上海应用技术学院 一种超声逼晶法提纯化合物的方法
CN105664816B (zh) * 2016-03-17 2017-11-03 杭州成功超声设备有限公司 将基于振幅控制的超声波设备用于化工装置的三步式方法
EP3369468A1 (en) * 2017-02-23 2018-09-05 Covaris, Inc. Acoustic energy-based control of particle count in crystallization
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CN110330335A (zh) * 2019-07-19 2019-10-15 中国工程物理研究院化工材料研究所 铋基卤化物陶瓷材料、制备方法及x射线探测器
US11925907B2 (en) 2019-07-22 2024-03-12 Canopy Growth Corporation Continuous crystallization of cannabinoids in a stirred-tank reactor
CN110773079B (zh) * 2019-11-18 2022-03-01 江苏博迁新材料股份有限公司 一种超声喷雾法制备超细粉球的方法
CN112972384B (zh) * 2019-12-02 2022-03-18 长风药业股份有限公司 一种格隆溴铵和茚达特罗原料药微粉混合物的制备方法
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CN114307840B (zh) * 2022-01-08 2022-09-16 安徽省农业科学院棉花研究所 一种有机配方肥热返料设备
CN115634635B (zh) * 2022-10-20 2025-03-18 江苏瑞祥化工有限公司 一种高纯度粒状2,5-二氯苯胺的制备装置及制备方法

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GB0705159D0 (en) * 2007-03-19 2007-04-25 Prosonix Ltd Process for making crystals
GB0711680D0 (en) * 2007-06-18 2007-07-25 Prosonix Ltd Process
EP2360147A1 (en) * 2010-02-22 2011-08-24 CHIESI FARMACEUTICI S.p.A. Process for preparing crystalline particles of a salt of 8-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino] ethyl]-2(1H)-quinolinone (carmoterol)

Also Published As

Publication number Publication date
EP2134457A1 (en) 2009-12-23
CA2680105C (en) 2016-05-17
US20100018853A1 (en) 2010-01-28
JP5808830B2 (ja) 2015-11-10
CA2680105A1 (en) 2008-09-25
US20160001252A1 (en) 2016-01-07
US10143991B2 (en) 2018-12-04
JP2014094965A (ja) 2014-05-22
ES2701728T3 (es) 2019-02-25
IL200802A (en) 2013-04-30
RU2456066C2 (ru) 2012-07-20
US9162160B2 (en) 2015-10-20
GB2447761B (en) 2012-02-29
WO2008114052A1 (en) 2008-09-25
RU2009138325A (ru) 2011-04-27
GB2447761A (en) 2008-09-24
IL200802A0 (en) 2010-05-17
EP2134457B1 (en) 2018-09-12
GB0804995D0 (en) 2008-04-16
CN101636223A (zh) 2010-01-27
CN101636223B (zh) 2015-09-16
JP2010522154A (ja) 2010-07-01
BRPI0809275A2 (pt) 2014-10-14

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