GB0615211D0 - Asymmetric flouro-substituted polymethine dyes - Google Patents
Asymmetric flouro-substituted polymethine dyesInfo
- Publication number
- GB0615211D0 GB0615211D0 GB0615211A GB0615211A GB0615211D0 GB 0615211 D0 GB0615211 D0 GB 0615211D0 GB 0615211 A GB0615211 A GB 0615211A GB 0615211 A GB0615211 A GB 0615211A GB 0615211 D0 GB0615211 D0 GB 0615211D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- conjugates
- asymmetric
- dyes
- flouro
- well
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 239000000975 dye Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 abstract 2
- 238000001917 fluorescence detection Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 238000011503 in vivo imaging Methods 0.000 abstract 1
- 238000002372 labelling Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000012634 optical imaging Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000006862 quantum yield reaction Methods 0.000 abstract 1
- 238000010791 quenching Methods 0.000 abstract 1
- 230000000171 quenching effect Effects 0.000 abstract 1
- ANRHNWWPFJCPAZ-UHFFFAOYSA-M thionine Chemical compound [Cl-].C1=CC(N)=CC2=[S+]C3=CC(N)=CC=C3N=C21 ANRHNWWPFJCPAZ-UHFFFAOYSA-M 0.000 abstract 1
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Indole Compounds (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0615211A GB0615211D0 (en) | 2006-07-31 | 2006-07-31 | Asymmetric flouro-substituted polymethine dyes |
| CN 200780036717 CN101522815A (zh) | 2006-07-31 | 2007-07-31 | 不对称的氟取代的多次甲基染料 |
| PCT/GB2007/002907 WO2008015415A2 (en) | 2006-07-31 | 2007-07-31 | Asymmetric fluoro-substituted polymethine dyes |
| US12/375,239 US20090252687A1 (en) | 2006-07-31 | 2007-07-31 | Asymmetric fluoro-substituted polymethine dyes |
| JP2009522326A JP5341757B2 (ja) | 2006-07-31 | 2007-07-31 | 非対称フルオロ置換ポリメチン色素 |
| EP07789086A EP2046895A2 (en) | 2006-07-31 | 2007-07-31 | Asymmetric fluoro-substituted polymethine dyes |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0615211A GB0615211D0 (en) | 2006-07-31 | 2006-07-31 | Asymmetric flouro-substituted polymethine dyes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB0615211D0 true GB0615211D0 (en) | 2006-09-06 |
Family
ID=37006503
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB0615211A Ceased GB0615211D0 (en) | 2006-07-31 | 2006-07-31 | Asymmetric flouro-substituted polymethine dyes |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20090252687A1 (https=) |
| EP (1) | EP2046895A2 (https=) |
| JP (1) | JP5341757B2 (https=) |
| CN (1) | CN101522815A (https=) |
| GB (1) | GB0615211D0 (https=) |
| WO (1) | WO2008015415A2 (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0718967D0 (en) * | 2007-09-28 | 2007-11-07 | Ge Healthcare Ltd | Peptide imaging agents |
| GB0718957D0 (en) * | 2007-09-28 | 2007-11-07 | Ge Healthcare Ltd | Optical imaging agents |
| EP2201009B1 (en) | 2007-10-02 | 2016-10-26 | Thermo Fisher Scientific Inc. | Monomethine dyes |
| US10493169B2 (en) | 2009-02-06 | 2019-12-03 | Beth Israel Deaconess Medical Center | Use of charge-balanced imaging agents for determining renal function |
| JP5798043B2 (ja) | 2009-02-06 | 2015-10-21 | ベス・イスラエル・ディーコネス・メディカル・センター,インコーポレイテッド | 電荷均衡造影剤 |
| US8546586B2 (en) * | 2009-04-28 | 2013-10-01 | Wako Pure Chemical Industries, Ltd. | Pyrazole-based cyanine dye containing quaternary ammonium cation |
| TWI516264B (zh) * | 2010-05-06 | 2016-01-11 | 臺北醫學大學 | 芳香醯喹啉化合物 |
| CN103052690A (zh) * | 2010-06-29 | 2013-04-17 | 通用电气医疗集团股份有限公司 | 染料组合物和染料合成 |
| DE102010027016A1 (de) | 2010-07-09 | 2012-01-12 | Universitätsklinikum Jena | Steroid-Styrylfarbstoff-Konjugate zur Simulation und direkten lichtoptischen Detektion des Verhaltens von Steroiden im lebenden biologischen Gewebe und in Gegenwart von steroidbindenden Proteinen |
| GB201013808D0 (en) | 2010-08-18 | 2010-09-29 | Ge Healthcare Ltd | Peptide radiotracer compositions |
| US20130287689A1 (en) * | 2010-11-02 | 2013-10-31 | Life Technologies Corporation | Modified Hydrocyanine Dyes for the Detection of Reactive Oxygen Species |
| US9518981B2 (en) | 2012-03-30 | 2016-12-13 | Life Technologies Corporation | Modified nucleic acid binding cyanine dyes for the detection of reactive oxygen species |
| US9676787B2 (en) | 2012-08-28 | 2017-06-13 | Pierce Biotechnology, Inc. | Benzopyrylium compounds |
| CA2891280C (en) | 2012-11-24 | 2018-03-20 | Hangzhou Dac Biotech Co., Ltd. | Hydrophilic linkers and their uses for conjugation of drugs to cell binding molecules |
| EP2970318B1 (en) | 2013-03-14 | 2018-11-21 | Profusa, Inc. | Oxygen sensors comprising a polymer and a luminescent dye |
| GB201314936D0 (en) | 2013-08-21 | 2013-10-02 | Ge Healthcare Ltd | Radiolabelling method |
| GB201322456D0 (en) | 2013-12-18 | 2014-02-05 | Ge Healthcare Ltd | Radiotracer compositions and methods |
| CN104804463B (zh) * | 2015-03-10 | 2016-08-24 | 西安交通大学第一附属医院 | 用于靶向肿瘤组织的近红外荧光染色剂及制备方法和应用 |
| CN110352036B (zh) * | 2016-12-21 | 2022-11-15 | 普罗菲尤萨股份有限公司 | 可聚合的近红外染料 |
| EP3375353A1 (en) * | 2017-03-16 | 2018-09-19 | Universität Zürich | Photoacoustic imaging of inflamed tissue |
| WO2018187295A1 (en) | 2017-04-03 | 2018-10-11 | Massachusetts Institute Of Technology | Near and shortwave infrared polymethine dyes |
| EP3634397A4 (en) | 2017-06-05 | 2021-03-17 | The Regents of The University of California | HETEROCYCLYL POLYMETHINE-BASED IR CHROMOPHORES |
| CN111712468A (zh) * | 2017-12-22 | 2020-09-25 | 北卡罗莱纳州立大学 | 聚合物荧光团、包含其的组合物及制备和使用其的方法 |
| KR20210040953A (ko) | 2018-06-27 | 2021-04-14 | 프로퓨사 인코퍼레이티드 | 근적외선 글루코스 센서 |
| CN117368301B (zh) * | 2022-06-29 | 2026-04-14 | 中国科学院大连化学物理研究所 | 一种组织中巯基化合物的质谱成像检测方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5658751A (en) * | 1993-04-13 | 1997-08-19 | Molecular Probes, Inc. | Substituted unsymmetrical cyanine dyes with selected permeability |
| US6495692B1 (en) * | 1996-12-10 | 2002-12-17 | Abbott Laboratories | Helium-neon excitable reticulocyte dyes derivable from halolepidines |
| WO2000034394A2 (de) * | 1998-12-05 | 2000-06-15 | Otto Samuel Wolfbeis | Pyridin- und chinolin-farbstoffe als marker für biomoleküle, polymere, arzneistoffe und partikel |
| DE19917713A1 (de) * | 1999-04-09 | 2000-10-19 | Diagnostikforschung Inst | Kurzkettige Peptid-Farbstoffkonjugate als Konstrastmittel für die optische Diagnostik |
| TR201809435T4 (tr) * | 2000-01-19 | 2018-07-23 | Abbvie Inc | Geliştirilmiş farmasötik formülasyonlar. |
| EP1283855B1 (de) * | 2000-05-23 | 2005-11-02 | Dyomics GmbH | Stabile nir-marker-farbstoffe auf der basis von benzopyrylium-polymethinen |
| BRPI0210886B8 (pt) * | 2001-07-10 | 2021-05-25 | Amersham Health As | composto, composição farmacêutica, uso de um composto, e, métodos de geração de imagens, de monitoração do efeito do tratamento de um corpo humano ou animal com uma droga para combater uma condição associada com câncer e de tratamento de câncer ou de uma doença relacionada em um corpo humano ou animal |
| TWI244494B (en) * | 2003-05-14 | 2005-12-01 | Ritek Corp | Optical recording medium dye |
| CA2599709A1 (en) * | 2005-03-09 | 2006-09-21 | Cepheid | Polar dyes |
-
2006
- 2006-07-31 GB GB0615211A patent/GB0615211D0/en not_active Ceased
-
2007
- 2007-07-31 JP JP2009522326A patent/JP5341757B2/ja not_active Expired - Fee Related
- 2007-07-31 EP EP07789086A patent/EP2046895A2/en not_active Withdrawn
- 2007-07-31 WO PCT/GB2007/002907 patent/WO2008015415A2/en not_active Ceased
- 2007-07-31 US US12/375,239 patent/US20090252687A1/en not_active Abandoned
- 2007-07-31 CN CN 200780036717 patent/CN101522815A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2009545645A (ja) | 2009-12-24 |
| WO2008015415A2 (en) | 2008-02-07 |
| EP2046895A2 (en) | 2009-04-15 |
| WO2008015415A3 (en) | 2008-05-08 |
| US20090252687A1 (en) | 2009-10-08 |
| CN101522815A (zh) | 2009-09-02 |
| JP5341757B2 (ja) | 2013-11-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AT | Applications terminated before publication under section 16(1) |