US341426A
(en)
|
|
1886-05-04 |
|
Gun-sight |
US341453A
(en)
|
|
1886-05-11 |
|
Paul cleec |
US4741900A
(en)
|
1982-11-16 |
1988-05-03 |
Cytogen Corporation |
Antibody-metal ion complexes
|
GB8308235D0
(en)
|
1983-03-25 |
1983-05-05 |
Celltech Ltd |
Polypeptides
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
JPS6147500A
(ja)
|
1984-08-15 |
1986-03-07 |
Res Dev Corp Of Japan |
キメラモノクロ−ナル抗体及びその製造法
|
EP0173494A3
(de)
|
1984-08-27 |
1987-11-25 |
The Board Of Trustees Of The Leland Stanford Junior University |
Chimäre Rezeptoren durch Verbindung und Expression von DNS
|
GB8422238D0
(en)
|
1984-09-03 |
1984-10-10 |
Neuberger M S |
Chimeric proteins
|
JPS61134325A
(ja)
|
1984-12-04 |
1986-06-21 |
Teijin Ltd |
ハイブリツド抗体遺伝子の発現方法
|
WO1986005807A1
(en)
|
1985-04-01 |
1986-10-09 |
Celltech Limited |
Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same
|
US4676980A
(en)
|
1985-09-23 |
1987-06-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Target specific cross-linked heteroantibodies
|
EP0247091B1
(de)
|
1985-11-01 |
1993-09-29 |
Xoma Corporation |
Modulare einheit von antikörpergenen, daraus hergestellte antikörper und verwendung
|
GB8601597D0
(en)
|
1986-01-23 |
1986-02-26 |
Wilson R H |
Nucleotide sequences
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
US5258498A
(en)
|
1987-05-21 |
1993-11-02 |
Creative Biomolecules, Inc. |
Polypeptide linkers for production of biosynthetic proteins
|
GB8717430D0
(en)
|
1987-07-23 |
1987-08-26 |
Celltech Ltd |
Recombinant dna product
|
AU622426B2
(en)
|
1987-12-11 |
1992-04-09 |
Abbott Laboratories |
Assay using template-dependent nucleic acid probe reorganization
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
EP0768377A1
(de)
|
1988-09-02 |
1997-04-16 |
Protein Engineering Corporation |
Herstellung und Auswahl von Rekombinantproteinen mit verschiedenen Bindestellen
|
DE68913658T3
(de)
|
1988-11-11 |
2005-07-21 |
Stratagene, La Jolla |
Klonierung von Immunglobulin Sequenzen aus den variablen Domänen
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
US5028535A
(en)
|
1989-01-10 |
1991-07-02 |
Biosite Diagnostics, Inc. |
Threshold ligand-receptor assay
|
US5939272A
(en)
|
1989-01-10 |
1999-08-17 |
Biosite Diagnostics Incorporated |
Non-competitive threshold ligand-receptor assays
|
US6291158B1
(en)
|
1989-05-16 |
2001-09-18 |
Scripps Research Institute |
Method for tapping the immunological repertoire
|
US5780225A
(en)
|
1990-01-12 |
1998-07-14 |
Stratagene |
Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules
|
AU7247191A
(en)
|
1990-01-11 |
1991-08-05 |
Molecular Affinities Corporation |
Production of antibodies using gene libraries
|
US5922615A
(en)
|
1990-03-12 |
1999-07-13 |
Biosite Diagnostics Incorporated |
Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
US6172197B1
(en)
|
1991-07-10 |
2001-01-09 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
DE69127627T2
(de)
|
1990-08-29 |
1998-02-19 |
Genpharm Int |
Produktion und Nützung nicht-menschliche transgentiere zur Produktion heterologe Antikörper
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
WO1992005282A1
(en)
|
1990-09-14 |
1992-04-02 |
Biosite Diagnostics, Inc. |
Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays
|
US5698426A
(en)
|
1990-09-28 |
1997-12-16 |
Ixsys, Incorporated |
Surface expression libraries of heteromeric receptors
|
ES2113940T3
(es)
|
1990-12-03 |
1998-05-16 |
Genentech Inc |
Metodo de enriquecimiento para variantes de proteinas con propiedades de union alteradas.
|
US5955377A
(en)
|
1991-02-11 |
1999-09-21 |
Biostar, Inc. |
Methods and kits for the amplification of thin film based assays
|
CA2108147C
(en)
|
1991-04-10 |
2009-01-06 |
Angray Kang |
Heterodimeric receptor libraries using phagemids
|
JPH06506688A
(ja)
|
1991-04-10 |
1994-07-28 |
バイオサイト・ダイアグノスティックス・インコーポレイテッド |
クロストークインヒビターおよびその使用
|
DE69231382T2
(de)
|
1991-04-12 |
2001-01-25 |
Biosite Diagnostics Inc., San Diego |
Neue konjugate und testverfahren für die gleichzeitige bestimmung von multiplen liganden
|
EP0590067A1
(de)
|
1991-06-14 |
1994-04-06 |
Xoma Corporation |
Mikrobiell hergestellte antikörper-fragmente und deren konjugate
|
WO1993008829A1
(en)
|
1991-11-04 |
1993-05-13 |
The Regents Of The University Of California |
Compositions that mediate killing of hiv-infected cells
|
EP2224006A1
(de)
|
1991-12-02 |
2010-09-01 |
MedImmune Limited |
Herstellung von Autoantikörpern auf Phagenoberflächen ausgehend von Antikörpersegmentbibliotheken
|
ATE463573T1
(de)
|
1991-12-02 |
2010-04-15 |
Medimmune Ltd |
Herstellung von autoantikörpern auf phagenoberflächen ausgehend von antikörpersegmentbibliotheken
|
US5733743A
(en)
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
US6019944A
(en)
|
1992-05-21 |
2000-02-01 |
Biosite Diagnostics, Inc. |
Diagnostic devices and apparatus for the controlled movement of reagents without membranes
|
US6143576A
(en)
|
1992-05-21 |
2000-11-07 |
Biosite Diagnostics, Inc. |
Non-porous diagnostic devices for the controlled movement of reagents
|
US5494829A
(en)
|
1992-07-31 |
1996-02-27 |
Biostar, Inc. |
Devices and methods for detection of an analyte based upon light interference
|
EP0656064B1
(de)
|
1992-08-17 |
1997-03-05 |
Genentech, Inc. |
Bispezifische immunoadhesine
|
US6765087B1
(en)
|
1992-08-21 |
2004-07-20 |
Vrije Universiteit Brussel |
Immunoglobulins devoid of light chains
|
IL108499A
(en)
*
|
1993-02-04 |
2000-02-29 |
Lilly Co Eli |
Mammalian influx peptide transporter
|
WO1994025591A1
(en)
|
1993-04-29 |
1994-11-10 |
Unilever N.V. |
PRODUCTION OF ANTIBODIES OR (FUNCTIONALIZED) FRAGMENTS THEREOF DERIVED FROM HEAVY CHAIN IMMUNOGLOBULINS OF $i(CAMELIDAE)
|
US5824799A
(en)
|
1993-09-24 |
1998-10-20 |
Biosite Diagnostics Incorporated |
Hybrid phthalocyanine derivatives and their uses
|
EP0733070A1
(de)
|
1993-12-08 |
1996-09-25 |
Genzyme Corporation |
Herstellungsverfahen für spezifische Antikörper
|
SE9400088D0
(sv)
|
1994-01-14 |
1994-01-14 |
Kabi Pharmacia Ab |
Bacterial receptor structures
|
ES2247204T3
(es)
|
1994-01-31 |
2006-03-01 |
Trustees Of Boston University |
Bancos de anticuerpos policlonales.
|
US5516637A
(en)
|
1994-06-10 |
1996-05-14 |
Dade International Inc. |
Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage
|
US5616502A
(en)
|
1995-05-19 |
1997-04-01 |
Molecular Probes, Inc. |
Non-specific protein staining using merocyanine dyes
|
JP2978435B2
(ja)
|
1996-01-24 |
1999-11-15 |
チッソ株式会社 |
アクリロキシプロピルシランの製造方法
|
GB9608510D0
(en)
|
1996-04-25 |
1996-07-03 |
Medical Res Council |
Calcium dependent binding ligands
|
US6113855A
(en)
|
1996-11-15 |
2000-09-05 |
Biosite Diagnostics, Inc. |
Devices comprising multiple capillarity inducing surfaces
|
GB9624927D0
(en)
|
1996-11-29 |
1997-01-15 |
Oxford Glycosciences Uk Ltd |
Gels and their use
|
US5947124A
(en)
|
1997-03-11 |
1999-09-07 |
Biosite Diagnostics Incorporated |
Diagnostic for determining the time of a heart attack
|
GB9705949D0
(en)
*
|
1997-03-21 |
1997-05-07 |
Electrophoretics International |
Diagnosis of tumours and other abnormalities of body cells
|
US6057098A
(en)
|
1997-04-04 |
2000-05-02 |
Biosite Diagnostics, Inc. |
Polyvalent display libraries
|
US7135457B1
(en)
*
|
1997-05-15 |
2006-11-14 |
Cytogen Corporation |
Random peptides that bind to gastro-intestinal tract (GIT) transport receptors and related methods
|
US6703362B1
(en)
*
|
1997-05-15 |
2004-03-09 |
Cytogen Corporation |
Random peptides that bind to gastro-intestinal tract (GIT) transport receptors and related methods
|
US7053177B1
(en)
*
|
1997-05-15 |
2006-05-30 |
Cytogen Corporation |
Random peptides that bind to gastro-intestinal tract (GIT) transport receptors and related methods
|
GB9710582D0
(en)
|
1997-05-22 |
1997-07-16 |
Oxford Glycosciences Uk Ltd |
A method for de novo peptide sequence determination
|
US6064654A
(en)
|
1997-06-18 |
2000-05-16 |
Dialogic Corporation |
Internet facsimile timing technique
|
GB9722131D0
(en)
|
1997-10-20 |
1997-12-17 |
Medical Res Council |
Method
|
US6335446B1
(en)
|
1998-10-05 |
2002-01-01 |
Oxford Glycosciences (Uk) Ltd. |
Quinolinium- and pyridinium-based fluorescent dye compounds
|
US6699973B1
(en)
*
|
1998-11-19 |
2004-03-02 |
Elan Corporation, Plc |
Antibodies to peptides that target GIT receptors and related methods
|
CA2388450C
(en)
*
|
1999-10-20 |
2013-02-12 |
The Board Of Trustees Of The University Of Arkansas |
Tadg-15: an extracellular serine protease overexpressed in carcinomas
|
US7524635B2
(en)
|
2003-04-17 |
2009-04-28 |
Biosite Incorporated |
Methods and compositions for measuring natriuretic peptides and uses thereof
|
JP4303105B2
(ja)
|
2001-06-28 |
2009-07-29 |
ドマンティス リミテッド |
二重特異性リガンドとその利用
|
WO2004058821A2
(en)
|
2002-12-27 |
2004-07-15 |
Domantis Limited |
Dual specific single domain antibodies specific for a ligand and for the receptor of the ligand
|
WO2003020934A1
(en)
*
|
2001-08-31 |
2003-03-13 |
Diadexus, Inc. |
Compositions and methods relating to colon specific genes and proteins
|
US20030232350A1
(en)
*
|
2001-11-13 |
2003-12-18 |
Eos Biotechnology, Inc. |
Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer
|
US20030134794A1
(en)
*
|
2001-11-20 |
2003-07-17 |
Madison Edwin L. |
Nucleic acid molecules encoding serine protease 17, the encoded polypeptides and methods based thereon
|
GB0208331D0
(en)
*
|
2002-04-11 |
2002-05-22 |
Oxford Glycosciences Uk Ltd |
Proteins
|
ATE328906T1
(de)
|
2002-06-28 |
2006-06-15 |
Domantis Ltd |
Dual-specifische liganden mit erhöhter halbwertszeit
|
AU2002951346A0
(en)
*
|
2002-09-05 |
2002-09-26 |
Garvan Institute Of Medical Research |
Diagnosis of ovarian cancer
|
EP1558645B1
(de)
|
2002-11-08 |
2011-07-27 |
Ablynx N.V. |
Stabilisierte einzel-domänen-antikörper in einer pharmazeutischen zusammensetzung ausgestaltet für inhalation
|
WO2004044178A2
(en)
*
|
2002-11-13 |
2004-05-27 |
Genentech, Inc. |
Methods and compositions for diagnosing dysplasia
|
EP1627062A1
(de)
|
2003-05-14 |
2006-02-22 |
Domantis Limited |
Verfahren zur gewinnung aus einem polypeptid - repertoire von polypeptiden, die sich reversibel entfalten
|
AU2004220325B2
(en)
|
2003-06-30 |
2011-05-12 |
Domantis Limited |
Polypeptides
|
US20100190150A1
(en)
*
|
2004-01-07 |
2010-07-29 |
Bristol-Myers Squibb Company |
Biomarkers and methods for determining sensitivity to epidermal growth factor receptor modulators
|
DE102004023187A1
(de)
*
|
2004-05-11 |
2005-12-01 |
Ganymed Pharmaceuticals Ag |
Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie
|
WO2006079372A1
(en)
|
2005-01-31 |
2006-08-03 |
Ablynx N.V. |
Method for generating variable domain sequences of heavy chain antibodies
|
DE102008006841B4
(de)
|
2008-01-30 |
2013-07-11 |
Wolfram Kangler |
Verfahren und Vorrichtung zum Betrieb einer Brennkraftmaschine mit einem flüssigen Kraftstoffgemisch
|
US9002545B2
(en)
|
2011-01-07 |
2015-04-07 |
Wabtec Holding Corp. |
Data improvement system and method
|