GB0215509D0 - Marker genes - Google Patents

Marker genes

Info

Publication number
GB0215509D0
GB0215509D0 GBGB0215509.1A GB0215509A GB0215509D0 GB 0215509 D0 GB0215509 D0 GB 0215509D0 GB 0215509 A GB0215509 A GB 0215509A GB 0215509 D0 GB0215509 D0 GB 0215509D0
Authority
GB
United Kingdom
Prior art keywords
marker genes
genes
marker
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0215509.1A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Priority to GBGB0215509.1A priority Critical patent/GB0215509D0/en
Publication of GB0215509D0 publication Critical patent/GB0215509D0/en
Priority to CNA038187833A priority patent/CN1688715A/zh
Priority to BR0312405-3A priority patent/BR0312405A/pt
Priority to US10/518,575 priority patent/US20060008804A1/en
Priority to PCT/EP2003/007111 priority patent/WO2004005544A2/en
Priority to EP07119607A priority patent/EP1925677A3/en
Priority to JP2004518691A priority patent/JP2005531321A/ja
Priority to CA002493860A priority patent/CA2493860A1/en
Priority to AU2003250879A priority patent/AU2003250879B2/en
Priority to EP03762612A priority patent/EP1521847A2/en
Priority to IL16588304A priority patent/IL165883A0/xx
Priority to JP2009233624A priority patent/JP2010042019A/ja
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
GBGB0215509.1A 2002-07-04 2002-07-04 Marker genes Ceased GB0215509D0 (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
GBGB0215509.1A GB0215509D0 (en) 2002-07-04 2002-07-04 Marker genes
EP03762612A EP1521847A2 (en) 2002-07-04 2003-07-03 Marker genes for determining renal toxicity
PCT/EP2003/007111 WO2004005544A2 (en) 2002-07-04 2003-07-03 Marker genes for determining renal toxicity
BR0312405-3A BR0312405A (pt) 2002-07-04 2003-07-03 Genes marcadores
US10/518,575 US20060008804A1 (en) 2002-07-04 2003-07-03 Marker genes
CNA038187833A CN1688715A (zh) 2002-07-04 2003-07-03 用于确定肾中毒的标记基因
EP07119607A EP1925677A3 (en) 2002-07-04 2003-07-03 Marker genes for determining renal toxicity
JP2004518691A JP2005531321A (ja) 2002-07-04 2003-07-03 マーカー遺伝子
CA002493860A CA2493860A1 (en) 2002-07-04 2003-07-03 Marker genes for determining renal toxicity
AU2003250879A AU2003250879B2 (en) 2002-07-04 2003-07-03 Marker genes for determining renal toxicity
IL16588304A IL165883A0 (en) 2002-07-04 2004-12-20 Marker genes for determining renal toxicity
JP2009233624A JP2010042019A (ja) 2002-07-04 2009-10-07 マーカー遺伝子

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0215509.1A GB0215509D0 (en) 2002-07-04 2002-07-04 Marker genes

Publications (1)

Publication Number Publication Date
GB0215509D0 true GB0215509D0 (en) 2002-08-14

Family

ID=9939850

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0215509.1A Ceased GB0215509D0 (en) 2002-07-04 2002-07-04 Marker genes

Country Status (10)

Country Link
US (1) US20060008804A1 (enExample)
EP (2) EP1925677A3 (enExample)
JP (2) JP2005531321A (enExample)
CN (1) CN1688715A (enExample)
AU (1) AU2003250879B2 (enExample)
BR (1) BR0312405A (enExample)
CA (1) CA2493860A1 (enExample)
GB (1) GB0215509D0 (enExample)
IL (1) IL165883A0 (enExample)
WO (1) WO2004005544A2 (enExample)

Families Citing this family (62)

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CA2412734A1 (en) 2000-06-16 2001-12-27 Biogen, Inc. Renal regulatory elements and methods of use thereof
DE60224275T2 (de) 2001-06-01 2008-12-11 Biogen Idec Ma Inc., Cambridge Moleküle und verfahren zur inhibierung der freisetzung von kim-1
AU2003299925B2 (en) 2002-12-30 2011-10-27 Biogen Ma Inc. KIM-1 antagonists and use to modulate immune system
WO2005107793A2 (en) * 2004-05-06 2005-11-17 The Trustees Of Columbia University Ngal for reduction and amelioration of ischemic and nephrotoxic injuries
US20050272101A1 (en) * 2004-06-07 2005-12-08 Prasad Devarajan Method for the early detection of renal injury
ES2622467T3 (es) * 2004-12-20 2017-07-06 Antibodyshop A/S Determinación de lipocalina asociada a gelatinasa de neutrófilos (NGAL) como marcador diagnóstico para trastornos renales
CN103751780A (zh) 2005-03-02 2014-04-30 比奥根艾迪克Ma公司 用于治疗th2介导的疾病的kim-1抗体
US20070037232A1 (en) * 2005-03-31 2007-02-15 Barasch Jonathan M Detection of NGAL in chronic renal disease
US20070087387A1 (en) 2005-04-21 2007-04-19 Prasad Devarajan Method for the Early Detection of Renal Disease Using Proteomics
US7700299B2 (en) 2005-08-12 2010-04-20 Hoffmann-La Roche Inc. Method for predicting the response to a treatment
US20080090304A1 (en) * 2006-10-13 2008-04-17 Barasch Jonathan Matthew Diagnosis and monitoring of chronic renal disease using ngal
ATE539351T1 (de) 2006-05-30 2012-01-15 Antibodyshop As Verfahren zur schnellen beurteilung der schwere eines traumas
EP2064553B2 (en) * 2006-08-07 2023-06-07 Antibodyshop A/S Diagnostic test to exclude significant renal injury
EP2137538B1 (en) 2007-03-21 2014-04-09 Bioporto Diagnostics A/s Diagnostic test for renal injury
CN103399155A (zh) * 2007-03-26 2013-11-20 诺瓦提斯公司 用于监测肾功能的预测性的肾安全性生物标志物和生物标志物标签
US20090104649A1 (en) 2007-06-11 2009-04-23 Garovic Vesna D Markers for preeclampsia
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CN101910845A (zh) * 2007-11-15 2010-12-08 比奥波托诊断股份公司 个体分子形式的生物标志的诊断用途
EP2075343A1 (en) * 2007-12-21 2009-07-01 Gert Mayer A method of diagnosing a progressive disease
EP2279270B1 (en) * 2008-04-15 2014-06-18 Oberbauer, Rainer Markers of acute kidney failure
US7977110B2 (en) 2008-06-02 2011-07-12 Children's Hospital Medical Center Method for distinguishing between kidney dysfunctions
ES2341419B1 (es) * 2008-08-14 2011-05-03 Hospital Clinic I Provincial De Barcelona Wnt1 como biomarcador de daño renal.
US8394606B2 (en) * 2008-11-05 2013-03-12 Abbott Laboratories Neutrophil gelatinase-associated lipocalin (NGAL) protein isoforms enriched from urine and recombinant chinese hamster ovary (CHO) cells and related compositions, antibodies, and methods of enrichment, analysis and use
EP2913676A1 (en) * 2008-11-10 2015-09-02 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
JP5735922B2 (ja) * 2008-11-22 2015-06-17 アスチュート メディカル，インコーポレイテッド 腎損傷および腎不全の診断および予後のための方法
CN102301008B (zh) * 2009-01-19 2015-05-13 生物梅里埃公司 用于确定患者发生医院内感染的易感性以及确立败血性综合征进展的预后的方法
DK2391653T3 (en) * 2009-01-28 2015-02-09 Ind Tech Res Inst Biomarkers associated nephropathy
CA2770189A1 (en) * 2009-08-07 2011-02-10 Rules-Based Medicine, Inc. Methods and devices for detecting kidney transplant rejection
ES2530866T3 (es) 2009-12-21 2015-03-06 Mayo Foundation Marcador temprano de proteinuria en pacientes tratados con un tratamiento anti-VEGF
AU2010336392B2 (en) 2009-12-23 2014-01-23 Hill's Pet Nutrition, Inc. Compositions and methods for diagnosing and treating kidney disorders in a canine
JP2013529907A (ja) 2010-05-24 2013-07-25 ザ トラスティーズ オブ コロンビア ユニヴァーシティ イン ザ シティ オブ ニューヨーク Ｎｇａｌタンパク質変異体及びその使用
EP3578205A1 (en) 2010-08-06 2019-12-11 ModernaTX, Inc. A pharmaceutical formulation comprising engineered nucleic acids and medical use thereof
CN103429606A (zh) 2010-10-01 2013-12-04 现代治疗公司 设计核酸及其使用方法
CA2831613A1 (en) 2011-03-31 2012-10-04 Moderna Therapeutics, Inc. Delivery and formulation of engineered nucleic acids
JP5804629B2 (ja) * 2011-07-29 2015-11-04 株式会社メディクローム 遺伝子発現変動解析による化学物質の毒性評価方法
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
KR20140074293A (ko) * 2011-09-14 2014-06-17 바스프 에스이 신장 독성을 평가하기 위한 수단 및 방법
KR20190099538A (ko) 2011-10-03 2019-08-27 모더나 세라퓨틱스, 인코포레이티드 변형된 뉴클레오사이드, 뉴클레오타이드, 및 핵산, 및 이들의 용도
EP4144378A1 (en) 2011-12-16 2023-03-08 ModernaTX, Inc. Modified nucleoside, nucleotide, and nucleic acid compositions
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
AU2013243954A1 (en) 2012-04-02 2014-10-30 Moderna Therapeutics, Inc. Modified polynucleotides for the production of cosmetic proteins and peptides
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US9254311B2 (en) 2012-04-02 2016-02-09 Moderna Therapeutics, Inc. Modified polynucleotides for the production of proteins
CN104937095B (zh) * 2012-10-24 2019-06-07 因瑞金公司 肾细胞群及其用途
WO2014081980A2 (en) 2012-11-21 2014-05-30 The Trustees Of Columbia University In The City Of New York Mutant ngal proteins and uses thereof
DK2922554T3 (en) 2012-11-26 2022-05-23 Modernatx Inc Terminalt modificeret rna
US10420337B2 (en) 2013-03-15 2019-09-24 Lifeline Scientific, Inc. Transporter with a glucose sensor for determining viability of an organ or tissue
WO2014152030A1 (en) 2013-03-15 2014-09-25 Moderna Therapeutics, Inc. Removal of dna fragments in mrna production process
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
JP6297676B2 (ja) 2013-05-06 2018-03-20 日立化成株式会社 標的分子を捕捉するためのデバイス及び方法
BR112016007255A2 (pt) 2013-10-03 2017-09-12 Moderna Therapeutics Inc polinucleotídeos que codificam receptor de lipoproteína de baixa densidade
WO2015153860A1 (en) * 2014-04-04 2015-10-08 Somalogic, Inc. Glomerular filtration rate biomarkers and uses thereof
US10712349B2 (en) 2014-04-15 2020-07-14 The Brigham And Women's Hospital, Inc. Circulating KIM-1 levels for detection of pathologies associated with injury to, or cancer of, the kidney
WO2015160805A1 (en) * 2014-04-15 2015-10-22 The Brigham And Women's Hospital, Inc. Circulating kim-1 levels for detection of pathologies associated with injury to, or cancer of, the kidney
US10801066B2 (en) 2014-09-05 2020-10-13 American University Of Beirut Determination of risk for development of cardiovascular disease by measuring urinary levels of podocin and nephrin messenger RNA
EP3218521B1 (en) * 2014-11-12 2019-12-25 Hitachi Chemical Co., Ltd. Method for diagnosing organ injury
CN108271422A (zh) 2015-06-25 2018-07-10 株式会社国际电气通信基础技术研究所 基于器官间串扰系统的预测装置及预测程序
DE112016003948T5 (de) 2015-08-31 2018-05-09 City Of Sapporo Molekulare verfahren zum beurteilen einer urothelialen erkrankung
CN114778845A (zh) 2016-03-29 2022-07-22 无限生物制药公司 药物组合物或食品组合物及评价活性成分体内效果的方法
EP3438282A4 (en) * 2016-03-29 2020-05-06 Advanced Telecommunications Research Institute International METHOD FOR SCREENING CANDIDATE SUBSTANCES FOR AN ACTIVE COMPONENT TO PREVENT OR TREAT AT LEAST ONE SELECTED DISEASE IN THE KIDNEY HYPOFUNCTION GROUP, CHRONIC KIDNEY DISEASE AND KIDNEY DEFICIENCY
JP7012033B2 (ja) * 2016-06-17 2022-02-10 エフ．ホフマン－ラ ロシュ アーゲー インビトロ腎毒性スクリーニングアッセイ
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Also Published As

Publication number Publication date
CA2493860A1 (en) 2004-01-15
IL165883A0 (en) 2006-01-15
US20060008804A1 (en) 2006-01-12
BR0312405A (pt) 2005-04-26
EP1521847A2 (en) 2005-04-13
CN1688715A (zh) 2005-10-26
JP2005531321A (ja) 2005-10-20
EP1925677A2 (en) 2008-05-28
AU2003250879B2 (en) 2007-07-26
WO2004005544A2 (en) 2004-01-15
AU2003250879A1 (en) 2004-01-23
EP1925677A3 (en) 2008-07-02
JP2010042019A (ja) 2010-02-25
WO2004005544A3 (en) 2004-04-22

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)