FR3108502B1 - Dérivés de nicotinamide mononucléotides dans le traitement et la prévention des infections bactériennes - Google Patents
Dérivés de nicotinamide mononucléotides dans le traitement et la prévention des infections bactériennes Download PDFInfo
- Publication number
- FR3108502B1 FR3108502B1 FR2003085A FR2003085A FR3108502B1 FR 3108502 B1 FR3108502 B1 FR 3108502B1 FR 2003085 A FR2003085 A FR 2003085A FR 2003085 A FR2003085 A FR 2003085A FR 3108502 B1 FR3108502 B1 FR 3108502B1
- Authority
- FR
- France
- Prior art keywords
- prevention
- treatment
- bacterial infections
- nicotinamide mononucleotide
- mononucleotide derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 208000035143 Bacterial infection Diseases 0.000 title abstract 2
- 208000022362 bacterial infectious disease Diseases 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title abstract 2
- DAYLJWODMCOQEW-TURQNECASA-O NMN(+) Chemical class NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP(O)(O)=O)O2)O)=C1 DAYLJWODMCOQEW-TURQNECASA-O 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
DÉRIVÉS DE NICOTINAMIDE MONONUCLÉOTIDES DANS LE TRAITEMENT ET LA PRÉVENTION DES INFECTIONS BACTÉRIENNES La présente invention concerne un composé de formule (I) ou un sel et/ou solvate pharmaceutiquement acceptable de celui-ci ; (I) dans lequel X, R1, R2, R3, R4, R5, R6, R7, R8, Y, et sont tels que décrits dans les revendications, pour son utilisation dans le traitement et/ou la prévention des infections bactériennes.
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR2003085A FR3108502B1 (fr) | 2020-03-27 | 2020-03-27 | Dérivés de nicotinamide mononucléotides dans le traitement et la prévention des infections bactériennes |
US17/914,576 US20230210881A1 (en) | 2020-03-27 | 2021-03-26 | Nicotinamide mononucleotide derivatives for the treatment of bacterial infections |
JP2022558101A JP2023526726A (ja) | 2020-03-27 | 2021-03-26 | 細菌性感染症の処置のためのニコチンアミドモノヌクレオチド誘導体 |
PCT/EP2021/057938 WO2021191422A1 (fr) | 2020-03-27 | 2021-03-26 | Dérivés de nicotinamide mononucléotides pour le traitement des infections bactériennes |
CA3171744A CA3171744A1 (fr) | 2020-03-27 | 2021-03-26 | Derives de nicotinamide mononucleotides pour le traitement des infections bacteriennes |
CN202180033681.XA CN115697349A (zh) | 2020-03-27 | 2021-03-26 | 用于治疗细菌感染的烟酰胺单核苷酸衍生物 |
AU2021245030A AU2021245030A1 (en) | 2020-03-27 | 2021-03-26 | Nicotinamide mononucleotide derivatives for the treatment of bacterial infections |
EP21713440.2A EP4125929A1 (fr) | 2020-03-27 | 2021-03-26 | Dérivés de nicotinamide mononucléotides pour le traitement des infections bactériennes |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR2003085A FR3108502B1 (fr) | 2020-03-27 | 2020-03-27 | Dérivés de nicotinamide mononucléotides dans le traitement et la prévention des infections bactériennes |
FR2003085 | 2020-03-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR3108502A1 FR3108502A1 (fr) | 2021-10-01 |
FR3108502B1 true FR3108502B1 (fr) | 2022-09-23 |
Family
ID=70614296
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR2003085A Active FR3108502B1 (fr) | 2020-03-27 | 2020-03-27 | Dérivés de nicotinamide mononucléotides dans le traitement et la prévention des infections bactériennes |
Country Status (8)
Country | Link |
---|---|
US (1) | US20230210881A1 (fr) |
EP (1) | EP4125929A1 (fr) |
JP (1) | JP2023526726A (fr) |
CN (1) | CN115697349A (fr) |
AU (1) | AU2021245030A1 (fr) |
CA (1) | CA3171744A1 (fr) |
FR (1) | FR3108502B1 (fr) |
WO (1) | WO2021191422A1 (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2022129536A1 (fr) * | 2020-12-18 | 2022-06-23 | Nuvamid Sa | Dérivés de nicotinamide mononucléotide et leur utilisation dans la stimulation de l'expression de l'hémoglobine foetale |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG11201912267SA (en) * | 2017-06-19 | 2020-01-30 | Gangadhara Ganapati | Nicotinamide riboside derivatives and their uses |
US20220323477A1 (en) * | 2019-09-09 | 2022-10-13 | Nuvamid Sa | Use of nmn for the prevention and/or treatment of pain, and corresponding compositions |
-
2020
- 2020-03-27 FR FR2003085A patent/FR3108502B1/fr active Active
-
2021
- 2021-03-26 US US17/914,576 patent/US20230210881A1/en active Pending
- 2021-03-26 WO PCT/EP2021/057938 patent/WO2021191422A1/fr active Application Filing
- 2021-03-26 JP JP2022558101A patent/JP2023526726A/ja active Pending
- 2021-03-26 CN CN202180033681.XA patent/CN115697349A/zh active Pending
- 2021-03-26 AU AU2021245030A patent/AU2021245030A1/en active Pending
- 2021-03-26 CA CA3171744A patent/CA3171744A1/fr active Pending
- 2021-03-26 EP EP21713440.2A patent/EP4125929A1/fr active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2021245030A1 (en) | 2022-11-03 |
FR3108502A1 (fr) | 2021-10-01 |
EP4125929A1 (fr) | 2023-02-08 |
CA3171744A1 (fr) | 2021-09-30 |
US20230210881A1 (en) | 2023-07-06 |
WO2021191422A1 (fr) | 2021-09-30 |
JP2023526726A (ja) | 2023-06-23 |
CN115697349A (zh) | 2023-02-03 |
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Year of fee payment: 2 |
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PLSC | Publication of the preliminary search report |
Effective date: 20211001 |
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